chr3:194,383,090–194,383,793

chr3 : 194,383,090 – 194,383,793

703 bp 74 TFs 6 linked genes

This 703 bp open chromatin element is linked to 6 target genes and is bound by 74 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ATP13A3		103.6 kb	Distal	Multiome
ATP13A3-DT		103.7 kb	Distal	Multiome
TMEM44-AS1		200.6 kb	Distal	Multiome
HES1		247.3 kb	Distal	Multiome
TMEM44		250.0 kb	Distal	Multiome+HiCAR
LSG1		288.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

ChIP WA01 ENCSR000BQU.ATF2.WA01 255 bp overlap

Ahr::Arnt 1 dataset

Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap

BRD4 2 datasets

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 109 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 182 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 162 bp overlap

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

Motif DE_72h DE_72h-E2F2_MA0864.3 13 bp overlap

Motif DE_72h DE_72h-E2F4_MA0470.3 13 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 116 bp overlap

Motif DE_72h DE_72h-EBF1_MA0154.5 11 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 342 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 54 bp overlap

ESR1 3 datasets

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 186 bp overlap

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 331 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 308 bp overlap

EZH2 2 datasets

ChIP SF8628 GSE94834.EZH2.SF8628 318 bp overlap

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 344 bp overlap

Motif DE_72h DE_72h-Ebf4_MA2122.1 11 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 479 bp overlap

ChIP DE DE-FOXA2-2 455 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 566 bp overlap

ChIP DE DE-GATA4-2 602 bp overlap

ChIP foregut GSE117136.GATA4.foregut 273 bp overlap

GATA6 5 datasets

ChIP DE DE-GATA6-1 576 bp overlap

ChIP DE DE-GATA6-2 539 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 491 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 526 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 343 bp overlap

Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

GTF2F1 2 datasets

ChIP K-562 ENCSR377BLZ.GTF2F1.K-562 61 bp overlap

ChIP K-562 GSE120104.GTF2F1.K-562 56 bp overlap

Gfi1B 1 dataset

Motif DE_72h DE_72h-Gfi1B_MA0483.2 10 bp overlap

Motif DE_72h DE_72h-Gli1_MA1990.2 10 bp overlap

Motif DE_72h DE_72h-Gli2_MA0734.4 9 bp overlap

HOXC13 1 dataset

Motif DE_72h DE_72h-HOXC13_MA0907.2 9 bp overlap

IKZF2 1 dataset

Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap

INO80 1 dataset

ChIP Hep-G2 GSE107730.INO80.Hep-G2 316 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 490 bp overlap

NANOG 1 dataset

ChIP WA01 ENCSR000BMT.NANOG.WA01 144 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 152 bp overlap

NEUROG2 2 datasets

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 66 bp overlap

ChIP MRC-5_N_05DPT GSE75910.NEUROG2.MRC-5_N_05DPT 77 bp overlap

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

PITX1 1 dataset

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

POU2F1 1 dataset

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 202 bp overlap

PRDM1 1 dataset

Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap

RHOXF1 1 dataset

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

SCRT1 2 datasets

ChIP HEK293 ENCFF513YVP 138 bp overlap

ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 87 bp overlap

SCRT2 1 dataset

ChIP HEK293 ENCFF711QQB 70 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 595 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 468 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 335 bp overlap

SMARCA4 1 dataset

ChIP 22Rv1 GSE115615.SMARCA4.22Rv1 236 bp overlap

SOX10 1 dataset

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX13 1 dataset

Motif DE_72h DE_72h-SOX13_MA1120.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 528 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 703 bp overlap

Motif DE_72h DE_72h-SOX2_MA0143.5 7 bp overlap

SOX21 1 dataset

Motif DE_72h DE_72h-SOX21_MA0866.1 15 bp overlap

SOX4 2 datasets

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

ChIP MRC-5_1DPT GSE75910.SOX4.MRC-5_1DPT 55 bp overlap

Motif DE_72h DE_72h-SOX8_MA0868.3 7 bp overlap

Motif DE_72h DE_72h-SOX9_MA0077.2 8 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SPIB_MA0081.3 13 bp overlap

SRSF3 1 dataset

ChIP Hep-G2 GSE120104.SRSF3.Hep-G2 97 bp overlap

STAT1 1 dataset

Motif DE_72h DE_72h-STAT1_MA0137.4 9 bp overlap

STAT3 1 dataset

Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap

Motif DE_72h DE_72h-Sox1_MA0870.1 15 bp overlap

Sox17 1 dataset

Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap

Motif DE_72h DE_72h-Sox3_MA0514.3 7 bp overlap

Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap

Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap

Stat4 1 dataset

Motif DE_72h DE_72h-Stat4_MA0518.2 10 bp overlap

Stat5a 1 dataset

Motif DE_72h DE_72h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_72h DE_72h-Stat5aStat5b_MA0519.2 9 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 265 bp overlap

TFAP2A 1 dataset

Motif DE_72h DE_72h-TFAP2A_MA0872.1 13 bp overlap

TFAP2C 1 dataset

Motif DE_72h DE_72h-TFAP2C_MA0815.1 13 bp overlap

TRIM28 1 dataset

ChIP HCT-116 GSE72622.TRIM28.HCT-116 87 bp overlap

Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap

Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap

ZNF143 1 dataset

ChIP MCF-7 GSE76454.ZNF143.MCF-7 160 bp overlap

ZNF354C 1 dataset

Motif DE_72h DE_72h-ZNF354C_MA0130.1 6 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 254 bp overlap

ZSCAN21 1 dataset

Motif DE_72h DE_72h-ZSCAN21_MA2336.1 7 bp overlap