chr3:48,372,864–48,373,543

chr3 : 48,372,864 – 48,373,543

679 bp 49 TFs 14 linked genes

This 679 bp open chromatin element is linked to 14 target genes and is bound by 49 transcription factors.

Linked Genes

14 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PLXNB1		56.3 kb	Distal	Multiome+HiCAR
CCDC51		66.9 kb	Distal	Multiome
TMA7		67.0 kb	Distal	Multiome
NME6		71.9 kb	Distal	Multiome+HiCAR
ATRIP		73.5 kb	Distal	Multiome
SHISA5		130.9 kb	Distal	Multiome
ZNF589		132.1 kb	Distal	Multiome
PFKFB4		183.8 kb	Distal	Multiome
CDC25A		184.9 kb	Distal	Multiome
COL7A1		191.8 kb	Distal	Multiome
UQCRC1		236.4 kb	Distal	Multiome
SLC26A6		262.2 kb	Distal	Multiome
MAP4		284.4 kb	Distal	Multiome
CELSR3		289.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

49 transcription factors

ChIP LNCaP_1F5_SIFOXA1 GSE30623.AR.LNCaP_1F5_SIFOXA1 234 bp overlap

ChIP LNCaP_R1881 GSE69043.AR.LNCaP_R1881 193 bp overlap

ChIP VCaP_R1881_30M GSE84432.AR.VCaP_R1881_30M 139 bp overlap

CBFA2T3 1 dataset

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 394 bp overlap

ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 114 bp overlap

CLOCK 1 dataset

ChIP U2OS GSE44236.CLOCK.U2OS 187 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 467 bp overlap

EBF3_P177L 1 dataset

ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 211 bp overlap

ChIP K562 ENCFF511ZZZ 120 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 258 bp overlap

ESR1 5 datasets

ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 180 bp overlap

ChIP MCF-7_EtOH GSE136673.ESR1.MCF-7_EtOH 288 bp overlap

ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 180 bp overlap

ChIP T-47D GSE148277.ESR1.T-47D 392 bp overlap

ChIP breast-cancer_3487 GSE126004.ESR1.breast-cancer_3487 221 bp overlap

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 346 bp overlap

ChIP SF8628 GSE94834.EZH2.SF8628 209 bp overlap

FOXA1 1 dataset

ChIP T-47D_JC4745 GSE126004.FOXA1.T-47D_JC4745 75 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 665 bp overlap

ChIP DE DE-FOXA2-2 629 bp overlap

GATA1 2 datasets

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 272 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 230 bp overlap

GATA2 7 datasets

ChIP K-562 ENCSR000DKA.GATA2.K-562 305 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 116 bp overlap

ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 245 bp overlap

ChIP SH-SY5Y ENCFF485YIB 405 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 477 bp overlap

ChIP SK-N-SH ENCFF764OZD 417 bp overlap

ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 275 bp overlap

GATA3 4 datasets

ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 213 bp overlap

ChIP MCF-7_E2 GSE60270.GATA3.MCF-7_E2 210 bp overlap

ChIP MCF-7_E2_Dex GSE81510.GATA3.MCF-7_E2_Dex 224 bp overlap

ChIP T-47D ENCSR000BMX.GATA3.T-47D 260 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 256 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 663 bp overlap

ChIP DE DE-GATA4-2 679 bp overlap

ChIP G296S GSE85628.GATA4.G296S 189 bp overlap

ChIP G296S_2 GSE85628.GATA4.G296S_2 189 bp overlap

ChIP foregut GSE117136.GATA4.foregut 558 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 606 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 531 bp overlap

GATA6 13 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 178 bp overlap

ChIP DE DE-GATA6-1 668 bp overlap

ChIP DE DE-GATA6-2 679 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 271 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 618 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 376 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 356 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 504 bp overlap

ChIP foregut GSE117136.GATA6.foregut 598 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 339 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 522 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 313 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 356 bp overlap

ChIP Hep-G2 ENCSR528PSI.HLF.Hep-G2 123 bp overlap

ChIP HepG2 ENCFF854JLR 245 bp overlap

IKZF1 4 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 534 bp overlap

ChIP K562 ENCFF348IBL 348 bp overlap

ChIP K562 ENCFF771OHZ 222 bp overlap

ChIP K562 ENCFF771OHZ 456 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 139 bp overlap

ChIP islet ERP004003.MAFB.islet 234 bp overlap

MAFF 2 datasets

ChIP HeLa-S3 ENCSR140DSL.MAFF.HeLa-S3 119 bp overlap

ChIP HepG2 ENCFF452YUT 277 bp overlap

MAFK 4 datasets

ChIP A549 ENCFF371EPR 337 bp overlap

ChIP Hep-G2 ENCSR000EDZ.MAFK.Hep-G2 192 bp overlap

ChIP HepG2 ENCFF743ZOF 241 bp overlap

ChIP HepG2 ENCFF767LDG 257 bp overlap

MED1 4 datasets

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 356 bp overlap

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 281 bp overlap

ChIP MM1-S_JQ1_5000NM GSE49224.MED1.MM1-S_JQ1_5000NM 200 bp overlap

ChIP MM1-S_JQ1_5NM GSE49224.MED1.MM1-S_JQ1_5NM 66 bp overlap

ChIP K-562 ENCSR180NCY.MTA3.K-562 248 bp overlap

NFIL3 1 dataset

ChIP HepG2 ENCFF686VLI 337 bp overlap

NKX2-5 2 datasets

ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 411 bp overlap

ChIP hESC_sc-14033 GSE89457.NKX2-5.hESC_sc-14033 359 bp overlap

NR3C1 1 dataset

ChIP T47D-A1-2_Dex GSE112491.NR3C1.T47D-A1-2_Dex 107 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 223 bp overlap

ChIP T-47D_R5020-A1 GSE126859.PGR.T-47D_R5020-A1 174 bp overlap

POLR2A 1 dataset

ChIP body of pancreas ENCFF084VJR 55 bp overlap

RCOR1 1 dataset

ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 184 bp overlap

RUNX1 2 datasets

ChIP Jurkat GSE68976.RUNX1.Jurkat 113 bp overlap

ChIP Jurkat GSE76181.RUNX1.Jurkat 113 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 679 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 412 bp overlap

SMAD4 1 dataset

ChIP Caco-2 GSE112946.SMAD4.Caco-2 123 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 286 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 633 bp overlap

ChIP K-562 ENCSR788RSW.SOX6.K-562 241 bp overlap

STAT3 1 dataset

ChIP breast-cancer_3487 GSE126004.STAT3.breast-cancer_3487 350 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 243 bp overlap

TBX5 5 datasets

ChIP G296S GSE85628.TBX5.G296S 311 bp overlap

ChIP G296S_2 GSE85628.TBX5.G296S_2 311 bp overlap

ChIP G296S_4 GSE85628.TBX5.G296S_4 169 bp overlap

ChIP cardiomyocyte_5 GSE85628.TBX5.cardiomyocyte_5 280 bp overlap

ChIP hiPSC GSE81585.TBX5.hiPSC 203 bp overlap

TEAD1 1 dataset

ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 138 bp overlap

TRPS1 1 dataset

ChIP T-47D GSE107013.TRPS1.T-47D 210 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 166 bp overlap

ZNF316 1 dataset

ChIP K562 ENCFF838QCD 130 bp overlap

ZNF652 2 datasets

ChIP Hep-G2 ENCSR502GAX.ZNF652.Hep-G2 269 bp overlap

ChIP HepG2 ENCFF331VPZ 381 bp overlap