chr2 : 117,854,448 – 117,855,028
580 bp 71 TFs 4 linked genes
This 580 bp open chromatin element is linked to 4 target genes and is bound by 71 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000236255 18.7 kb Distal Multiome
DDX18 40.2 kb Distal Multiome
CCDC93 159.2 kb Distal Multiome
INSIG2 233.7 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:117,849,448 – 117,860,028
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
71 transcription factors
Source
Cell type
ARNTL 1 dataset
ChIP U2OS_trough_DMOG GSE85096.ARNTL.U2OS_trough_DMOG 294 bp overlap
Bach1::Mafk 1 dataset
Motif DE_60h DE_60h-Bach1Mafk_MA0591.2 12 bp overlap
CDX2 1 dataset
ChIP intestinal-cell GSE115314.CDX2.intestinal-cell 123 bp overlap
CTCF 4 datasets
ChIP HCT-116 ENCSR240PRQ.CTCF.HCT-116 233 bp overlap
ChIP Loucy ENCSR464DKE.CTCF.Loucy 160 bp overlap
ChIP endodermal cell ENCFF471YCZ 103 bp overlap
ChIP heart ENCSR232OFD.CTCF.heart 234 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF335XTP 273 bp overlap
ChIP BLaER1 ENCFF896HSY 282 bp overlap
DMRTA1 2 datasets
Motif DE_48h DE_48h-DMRTA1_MA1707.2 10 bp overlap
Motif DE_60h DE_60h-DMRTA1_MA1707.2 10 bp overlap
ELF1 2 datasets
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
Motif DE_60h DE_60h-ELF1_MA0473.4 9 bp overlap
ELF3 2 datasets
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
Motif DE_60h DE_60h-ELF3_MA0640.3 9 bp overlap
EOMES 4 datasets
Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 392 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 194 bp overlap
ChIP DE DE-FOXA2-1 580 bp overlap
ChIP DE DE-FOXA2-2 580 bp overlap
FOXH1 1 dataset
Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap
GATA2 4 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
GATA4 9 datasets
ChIP DE DE-GATA4-1 545 bp overlap
ChIP DE DE-GATA4-2 580 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 410 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 259 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 264 bp overlap
GATA5 4 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 16 datasets
ChIP DE DE-GATA6-1 477 bp overlap
ChIP DE DE-GATA6-2 580 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 554 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 565 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 468 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 475 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 552 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 575 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 498 bp overlap
ChIP foregut GSE117136.GATA6.foregut 338 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 262 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 338 bp overlap
Gata3 4 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HOXB8 2 datasets
ChIP CFPAC-1_HOXB8-OE GSE119930.HOXB8.CFPAC-1_HOXB8-OE 134 bp overlap
ChIP PANC-1 GSE119930.HOXB8.PANC-1 105 bp overlap
HOXC11 3 datasets
Motif DE_36h DE_36h-HOXC11_MA0651.3 11 bp overlap
Motif DE_48h DE_48h-HOXC11_MA0651.3 11 bp overlap
Motif DE_60h DE_60h-HOXC11_MA0651.3 11 bp overlap
Hnf1A 5 datasets
Motif DE_36h DE_36h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
Irf1 2 datasets
Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
JUN 4 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 307 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 293 bp overlap
ChIP DE_D2 S54-DE-d2-JUN-exp2 275 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 264 bp overlap
LDB1 1 dataset
ChIP HEP GSE52637.LDB1.HEP 108 bp overlap
Lef1 2 datasets
Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap
Motif DE_60h DE_60h-Lef1_MA0768.3 8 bp overlap
MAFF 1 dataset
Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap
MAFK 1 dataset
ChIP A549 ENCFF371EPR 105 bp overlap
MEIS1 3 datasets
Motif DE_36h DE_36h-MEIS1_MA1639.2 9 bp overlap
Motif DE_48h DE_48h-MEIS1_MA1639.2 9 bp overlap
Motif DE_60h DE_60h-MEIS1_MA1639.2 9 bp overlap
MGA 3 datasets
Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
MYB 1 dataset
Motif DE_60h DE_60h-MYB_MA0100.4 6 bp overlap
MYF6 1 dataset
Motif DE_60h DE_60h-MYF6_MA0667.1 10 bp overlap
Mafb 1 dataset
Motif DE_60h DE_60h-Mafb_MA0117.3 11 bp overlap
Mecom 4 datasets
Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 127 bp overlap
NRL 2 datasets
Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap
Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH4 GSE140115.PAX3-FOXO1.RH4 166 bp overlap
PROX1 4 datasets
Motif DE_36h DE_36h-PROX1_MA0794.1 12 bp overlap
Motif DE_48h DE_48h-PROX1_MA0794.1 12 bp overlap
Motif DE_60h DE_60h-PROX1_MA0794.1 12 bp overlap
Motif DE_72h DE_72h-PROX1_MA0794.1 12 bp overlap
Pgr 1 dataset
Motif DE_60h DE_60h-Pgr_MA2323.1 17 bp overlap
RFX4 1 dataset
Motif DE_60h DE_60h-RFX4_MA0799.3 13 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 352 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 460 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 546 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 433 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 413 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 504 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 426 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 520 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 467 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 287 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 323 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 558 bp overlap
SOX10 3 datasets
Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 326 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 349 bp overlap
STAT1_pS727 1 dataset
ChIP SET-2 GSE100566.STAT1_pS727.SET-2 234 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 283 bp overlap
TAL1 1 dataset
ChIP ProEs GSE59087.TAL1.ProEs 214 bp overlap
TBR1 3 datasets
Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap
TBX1 3 datasets
Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap
TBX15 3 datasets
Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap
TBX18 3 datasets
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TBX2 3 datasets
Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
TBX20 3 datasets
Motif DE_36h DE_36h-TBX20_MA0689.1 11 bp overlap
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap
TBX21 3 datasets
Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap
TBX3 3 datasets
Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
TBX4 3 datasets
Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap
TBX5 3 datasets
Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap
Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap
Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap
TCF7 2 datasets
Motif DE_48h DE_48h-TCF7_MA0769.3 7 bp overlap
Motif DE_60h DE_60h-TCF7_MA0769.3 7 bp overlap
TCF7L2 5 datasets
Motif DE_36h DE_36h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
TRPS1 4 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Tbx6 3 datasets
Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
ZBTB7B 2 datasets
Motif DE_48h DE_48h-ZBTB7B_MA0694.2 10 bp overlap
Motif DE_60h DE_60h-ZBTB7B_MA0694.2 10 bp overlap
ZBTB7C 2 datasets
Motif DE_48h DE_48h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_60h DE_60h-ZBTB7C_MA0695.2 8 bp overlap
ZFP42 4 datasets
Motif DE_36h DE_36h-ZFP42_MA1651.2 13 bp overlap
Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap
Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap
Motif DE_72h DE_72h-ZFP42_MA1651.2 13 bp overlap
ZNF157 5 datasets
Motif DE_36h DE_36h-ZNF157_MA2331.1 21 bp overlap
Motif DE_48h DE_48h-ZNF157_MA2331.1 21 bp overlap
Motif DE_48h DE_48h-ZNF157_MA2331.1 21 bp overlap
Motif DE_60h DE_60h-ZNF157_MA2331.1 21 bp overlap
Motif DE_60h DE_60h-ZNF157_MA2331.1 21 bp overlap
ZNF211 4 datasets
Motif DE_36h DE_36h-ZNF211_MA1974.2 10 bp overlap
Motif DE_48h DE_48h-ZNF211_MA1974.2 10 bp overlap
Motif DE_60h DE_60h-ZNF211_MA1974.2 10 bp overlap
Motif DE_72h DE_72h-ZNF211_MA1974.2 10 bp overlap
ZNF410 1 dataset
Motif DE_60h DE_60h-ZNF410_MA0752.2 16 bp overlap
ZNF701 2 datasets
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
ZSCAN16 3 datasets
Motif DE_36h DE_36h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_48h DE_48h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_60h DE_60h-ZSCAN16_MA2100.1 18 bp overlap
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