Involved in Golgi to plasma membrane transport and endocytic recycling. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for CCDC93. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CCDC93 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CCDC93, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr2:117,814,354–117,815,236 | 199.4 kb | Distal (>10kb) Multiome | 987 | |
| chr2:117,835,820–117,836,917 | 177.9 kb | Distal (>10kb) Multiome | 337 | |
| chr2:117,849,927–117,850,957 | 163.6 kb | Distal (>10kb) Multiome | 288 | |
| chr2:117,851,735–117,852,372 | 162.0 kb | Distal (>10kb) Multiome | 96 | |
| chr2:117,853,013–117,853,974 | 160.6 kb | Distal (>10kb) Multiome | 109 | |
| chr2:117,854,448–117,855,028 | 159.2 kb | Distal (>10kb) Multiome | 71 | |
| chr2:118,013,165–118,014,769 | 6 bp | At TSS Multiome | 833 | |
| chr2:118,087,899–118,089,495 | 74.3 kb | Distal (>10kb) Multiome | 907 | |
| chr2:118,185,218–118,186,863 | 172.4 kb | Distal (>10kb) Multiome | 532 | |
| chr2:118,224,106–118,225,489 | 210.4 kb | Distal (>10kb) Multiome | 219 | |
| chr2:118,255,734–118,256,893 | 242.4 kb | Distal (>10kb) Multiome | 49 | |
| chr2:118,309,731–118,310,680 | 296.0 kb | Distal (>10kb) Multiome | 280 | |
| chr2:118,310,862–118,311,497 | 297.1 kb | Distal (>10kb) Multiome | 111 |
Genomic view of the CCDC93 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.