chr19 : 20,371,834 – 20,372,343
509 bp 96 TFs 8 linked genes
This 509 bp open chromatin element is linked to 8 target genes and is bound by 96 transcription factors.
Linked Genes
8 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000293570 9.2 kb Proximal Proximity
ENSG00000291130 53.0 kb Distal Multiome
ENSG00000267383 133.6 kb Distal Multiome+HiCAR
ZNF737 193.8 kb Distal Multiome
ZNF486 204.8 kb Distal Multiome
ZNF626 289.6 kb Distal Multiome
ZNF90 294.0 kb Distal Multiome
ZNF431 770.0 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr19:20,366,834 – 20,377,343
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
96 transcription factors
Source
Cell type
ALX3 1 dataset
Motif DE_72h DE_72h-ALX3_MA0634.2 6 bp overlap
ARGFX 1 dataset
Motif DE_72h DE_72h-ARGFX_MA1463.2 8 bp overlap
BCL11A 1 dataset
Motif DE_72h DE_72h-BCL11A_MA2324.1 7 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 156 bp overlap
DRGX 1 dataset
Motif DE_72h DE_72h-DRGX_MA1481.2 6 bp overlap
EMX1 1 dataset
Motif DE_72h DE_72h-EMX1_MA0612.3 6 bp overlap
EMX2 1 dataset
Motif DE_72h DE_72h-EMX2_MA0886.2 6 bp overlap
EN1 1 dataset
Motif DE_72h DE_72h-EN1_MA0027.3 6 bp overlap
EP300 1 dataset
ChIP H1 ENCFF927IYK 297 bp overlap
ESX1 1 dataset
Motif DE_72h DE_72h-ESX1_MA0644.3 7 bp overlap
EVX1 1 dataset
Motif DE_72h DE_72h-EVX1_MA0887.2 6 bp overlap
EVX2 1 dataset
Motif DE_72h DE_72h-EVX2_MA0888.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 509 bp overlap
ChIP DE DE-FOXA2-2 509 bp overlap
FOXO1::FLI1 1 dataset
Motif DE_72h DE_72h-FOXO1FLI1_MA1956.2 13 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 509 bp overlap
ChIP DE DE-GATA4-2 509 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 315 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 509 bp overlap
ChIP DE DE-GATA6-2 509 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 509 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 509 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 509 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 509 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 509 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 471 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 298 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 255 bp overlap
GRHL2 1 dataset
Motif DE_72h DE_72h-GRHL2_MA1105.3 8 bp overlap
GSX1 1 dataset
Motif DE_72h DE_72h-GSX1_MA0892.2 6 bp overlap
GSX2 1 dataset
Motif DE_72h DE_72h-GSX2_MA0893.3 7 bp overlap
HOXA1 1 dataset
Motif DE_72h DE_72h-HOXA1_MA1495.2 6 bp overlap
HOXA2 1 dataset
Motif DE_72h DE_72h-HOXA2_MA0900.3 6 bp overlap
HOXA3 1 dataset
Motif DE_72h DE_72h-HOXA3_MA2119.1 7 bp overlap
HOXA5 1 dataset
Motif DE_72h DE_72h-HOXA5_MA0158.2 8 bp overlap
HOXA6 1 dataset
Motif DE_72h DE_72h-HOXA6_MA1497.2 7 bp overlap
HOXB1 1 dataset
Motif DE_72h DE_72h-HOXB1_MA2093.1 7 bp overlap
HOXB2 1 dataset
Motif DE_72h DE_72h-HOXB2_MA0902.3 6 bp overlap
HOXB3 1 dataset
Motif DE_72h DE_72h-HOXB3_MA0903.2 6 bp overlap
HOXB5 1 dataset
Motif DE_72h DE_72h-HOXB5_MA0904.3 6 bp overlap
HOXB6 1 dataset
Motif DE_72h DE_72h-HOXB6_MA1500.2 7 bp overlap
HOXB7 1 dataset
Motif DE_72h DE_72h-HOXB7_MA1501.2 7 bp overlap
HOXB8 1 dataset
Motif DE_72h DE_72h-HOXB8_MA1502.2 7 bp overlap
HOXC8 1 dataset
Motif DE_72h DE_72h-HOXC8_MA1505.2 6 bp overlap
HOXD3 1 dataset
Motif DE_72h DE_72h-HOXD3_MA0912.2 8 bp overlap
HOXD8 1 dataset
Motif DE_72h DE_72h-HOXD8_MA0910.3 7 bp overlap
Hand1 1 dataset
Motif DE_72h DE_72h-Hand1_MA2123.1 9 bp overlap
ISX 1 dataset
Motif DE_72h DE_72h-ISX_MA0654.2 6 bp overlap
JUN 2 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 290 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 377 bp overlap
LHX5 1 dataset
Motif DE_72h DE_72h-LHX5_MA1519.2 7 bp overlap
LHX6 1 dataset
Motif DE_72h DE_72h-LHX6_MA0658.2 8 bp overlap
LMX1A 1 dataset
Motif DE_72h DE_72h-LMX1A_MA0702.3 7 bp overlap
LMX1B 1 dataset
Motif DE_72h DE_72h-LMX1B_MA0703.3 8 bp overlap
Lhx1 1 dataset
Motif DE_72h DE_72h-Lhx1_MA1518.3 10 bp overlap
Lhx4 1 dataset
Motif DE_72h DE_72h-Lhx4_MA0704.2 6 bp overlap
Lhx8 1 dataset
Motif DE_72h DE_72h-Lhx8_MA0705.2 6 bp overlap
MEIS1 3 datasets
Motif DE_48h DE_48h-MEIS1_MA1639.2 9 bp overlap
Motif DE_60h DE_60h-MEIS1_MA1639.2 9 bp overlap
Motif DE_72h DE_72h-MEIS1_MA1639.2 9 bp overlap
MEOX1 1 dataset
Motif DE_72h DE_72h-MEOX1_MA0661.2 7 bp overlap
MEOX2 1 dataset
Motif DE_72h DE_72h-MEOX2_MA0706.2 7 bp overlap
MIXL1 1 dataset
Motif DE_72h DE_72h-MIXL1_MA0662.2 6 bp overlap
MNX1 1 dataset
Motif DE_72h DE_72h-MNX1_MA0707.3 6 bp overlap
Mecom 3 datasets
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 374 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 377 bp overlap
ChIP hESC GSE18292.NANOG.hESC 95 bp overlap
NEUROD1 1 dataset
ChIP D283-Med GSE92582.NEUROD1.D283-Med 189 bp overlap
NKX6-1 1 dataset
Motif DE_72h DE_72h-NKX6-1_MA0674.2 7 bp overlap
NKX6-2 1 dataset
Motif DE_72h DE_72h-NKX6-2_MA0675.2 6 bp overlap
NOTO 1 dataset
Motif DE_72h DE_72h-NOTO_MA0710.2 7 bp overlap
Nfat5 1 dataset
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
PDX1 2 datasets
Motif DE_72h DE_72h-PDX1_MA0132.3 6 bp overlap
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 380 bp overlap
POU1F1 1 dataset
Motif DE_72h DE_72h-POU1F1_MA0784.3 14 bp overlap
POU2F1 1 dataset
Motif DE_72h DE_72h-POU2F1_MA0785.2 9 bp overlap
POU2F1::SOX2 1 dataset
Motif DE_72h DE_72h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 1 dataset
Motif DE_72h DE_72h-POU2F2_MA0507.3 13 bp overlap
POU3F2 1 dataset
Motif DE_72h DE_72h-POU3F2_MA0787.1 12 bp overlap
POU3F3 1 dataset
Motif DE_72h DE_72h-POU3F3_MA0788.1 13 bp overlap
POU3F4 1 dataset
Motif DE_72h DE_72h-POU3F4_MA0789.1 9 bp overlap
POU5F1 1 dataset
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 349 bp overlap
POU5F1B 1 dataset
Motif DE_72h DE_72h-POU5F1B_MA0792.1 9 bp overlap
POU6F1 1 dataset
Motif DE_72h DE_72h-POU6F1_MA0628.2 6 bp overlap
PPARA::RXRA 3 datasets
Motif DE_48h DE_48h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_72h DE_72h-PPARARXRA_MA1148.2 17 bp overlap
PRRX1 1 dataset
Motif DE_72h DE_72h-PRRX1_MA0716.2 6 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_72h DE_72h-Pou5f1Sox2_MA0142.1 15 bp overlap
Pparg::Rxra 3 datasets
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap
RARA 3 datasets
ChIP hiPSC_D2 GSE132532.RARA.hiPSC_D2 312 bp overlap
ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 225 bp overlap
ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 252 bp overlap
RAX2 1 dataset
Motif DE_72h DE_72h-RAX2_MA0717.2 6 bp overlap
RBPJ 1 dataset
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
RFX5 1 dataset
Motif DE_72h DE_72h-RFX5_MA0510.3 14 bp overlap
SHOX 1 dataset
Motif DE_72h DE_72h-SHOX_MA0630.2 6 bp overlap
SMAD2 1 dataset
Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 310 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 343 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 344 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 418 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 445 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 417 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 509 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 426 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 292 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 220 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 258 bp overlap
SMARCC1 3 datasets
ChIP DE_D1 S15-DE-d1-BAF155-exp1 444 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 242 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 238 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 321 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 509 bp overlap
Shox2 1 dataset
Motif DE_72h DE_72h-Shox2_MA0720.2 6 bp overlap
TLX2 1 dataset
Motif DE_72h DE_72h-TLX2_MA1577.2 6 bp overlap
UNCX 1 dataset
Motif DE_72h DE_72h-UNCX_MA0721.2 6 bp overlap
VAX1 1 dataset
Motif DE_72h DE_72h-VAX1_MA0722.2 7 bp overlap
VAX2 1 dataset
Motif DE_72h DE_72h-VAX2_MA0723.3 6 bp overlap
VSX1 1 dataset
Motif DE_72h DE_72h-VSX1_MA0725.2 7 bp overlap
VSX2 1 dataset
Motif DE_72h DE_72h-VSX2_MA0726.2 7 bp overlap
ZIC1 1 dataset
Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap
ZIC4 1 dataset
Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap
ZIC5 1 dataset
Motif DE_72h DE_72h-ZIC5_MA1584.2 15 bp overlap
ZNF680 3 datasets
Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap
Motif DE_60h DE_60h-ZNF680_MA1729.2 11 bp overlap
Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap
mix-a 1 dataset
Motif DE_72h DE_72h-mix-a_MA0621.2 7 bp overlap
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