chr18 : 63,940,382 – 63,940,978

596 bp 79 TFs 1 linked gene

This 596 bp open chromatin element is linked to HMSD and is bound by 79 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
HMSD		8.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

79 transcription factors

BCL11A 1 dataset

Motif DE_12h DE_12h-BCL11A_MA2324.1 7 bp overlap

CTCF 8 datasets

Motif DE_12h DE_12h-CTCF_MA0139.2 15 bp overlap

Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap

Motif DE_12h DE_12h-CTCF_MA1930.2 33 bp overlap

Motif ES_0h ES_0h-CTCF_MA1929.2 31 bp overlap

ChIP H1 ENCFF764RHO 194 bp overlap

ChIP H9 ENCFF152GTF 263 bp overlap

ChIP endodermal cell ENCFF471YCZ 176 bp overlap

ChIP endodermal cell ENCFF471YCZ 89 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 252 bp overlap

FERD3L 1 dataset

Motif DE_12h DE_12h-FERD3L_MA1485.1 14 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

FOXA1 2 datasets

Motif DE_12h DE_12h-FOXA1_MA0148.5 8 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 349 bp overlap

ChIP DE DE-FOXA2-2 275 bp overlap

Motif DE_12h DE_12h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif DE_12h DE_12h-FOXA3_MA1683.2 7 bp overlap

FOXB1 1 dataset

Motif DE_12h DE_12h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_12h DE_12h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap

FOXD1 1 dataset

Motif DE_12h DE_12h-FOXD1_MA0031.2 7 bp overlap

FOXD2 1 dataset

Motif DE_12h DE_12h-FOXD2_MA0847.4 11 bp overlap

FOXD3 1 dataset

Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap

FOXE1 1 dataset

Motif DE_12h DE_12h-FOXE1_MA1487.3 12 bp overlap

FOXF2 1 dataset

Motif DE_12h DE_12h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_12h DE_12h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif DE_12h DE_12h-FOXI1_MA0042.2 7 bp overlap

FOXK1 1 dataset

Motif DE_12h DE_12h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_12h DE_12h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_12h DE_12h-FOXL1_MA0033.2 7 bp overlap

FOXN3 1 dataset

Motif DE_12h DE_12h-FOXN3_MA1489.1 8 bp overlap

FOXO4 1 dataset

Motif DE_12h DE_12h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_12h DE_12h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif DE_12h DE_12h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif DE_12h DE_12h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_12h DE_12h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif DE_12h DE_12h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif DE_12h DE_12h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif DE_12h DE_12h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_12h DE_12h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_12h DE_12h-Foxj3_MA0851.2 9 bp overlap

Foxl2 1 dataset

Motif DE_12h DE_12h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif DE_12h DE_12h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_12h DE_12h-Foxo3_MA0157.4 7 bp overlap

HIC2 2 datasets

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap

KLF1 1 dataset

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

KLF2 1 dataset

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

KLF4 1 dataset

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

NFATC3 1 dataset

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

NFKB1 2 datasets

Motif DE_12h DE_12h-NFKB1_MA0105.4 13 bp overlap

NFKB2 2 datasets

Motif DE_12h DE_12h-NFKB2_MA0778.2 11 bp overlap

Nfat5 1 dataset

Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap

Nfatc1 1 dataset

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

Nr2F6 1 dataset

Motif DE_12h DE_12h-Nr2F6_MA0728.1 15 bp overlap

PATZ1 1 dataset

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 243 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

RELA 1 dataset

Motif DE_12h DE_12h-RELA_MA0107.1 10 bp overlap

RORB 1 dataset

Motif DE_12h DE_12h-RORB_MA1150.2 10 bp overlap

RXRB 1 dataset

Motif DE_12h DE_12h-RXRB_MA1555.1 14 bp overlap

SIX2 1 dataset

Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap

SOX10 1 dataset

Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap

SOX4 1 dataset

Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap

SREBF1 2 datasets

Motif DE_12h DE_12h-SREBF1_MA0595.1 10 bp overlap

Motif DE_12h DE_12h-SREBF1_MA0829.3 10 bp overlap

SREBF2 1 dataset

Motif DE_12h DE_12h-SREBF2_MA0596.1 10 bp overlap

Sox11 1 dataset

Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap

TCF4 1 dataset

Motif DE_12h DE_12h-TCF4_MA0830.3 8 bp overlap

TGIF1 1 dataset

Motif DE_12h DE_12h-TGIF1_MA0796.1 12 bp overlap

TGIF2 1 dataset

Motif DE_12h DE_12h-TGIF2_MA0797.1 12 bp overlap

TGIF2LX 1 dataset

Motif DE_12h DE_12h-TGIF2LX_MA1571.1 12 bp overlap

TGIF2LY 1 dataset

Motif DE_12h DE_12h-TGIF2LY_MA1572.1 12 bp overlap

THAP1 2 datasets

Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap

Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap

THRB 1 dataset

Motif DE_12h DE_12h-THRB_MA1575.2 17 bp overlap

YY2 1 dataset

Motif DE_12h DE_12h-YY2_MA0748.3 7 bp overlap

ZBTB6 2 datasets

Motif DE_12h DE_12h-ZBTB6_MA1581.2 9 bp overlap

Motif ES_0h ES_0h-ZBTB6_MA1581.2 9 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZNF135 2 datasets

Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap

Motif ES_0h ES_0h-ZNF135_MA1587.1 14 bp overlap

ZNF317 1 dataset

Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap

ZNF343 1 dataset

Motif DE_12h DE_12h-ZNF343_MA1711.2 16 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

ZNF549 1 dataset

Motif DE_12h DE_12h-ZNF549_MA1728.2 8 bp overlap

ZNF667 1 dataset

Motif DE_12h DE_12h-ZNF667_MA1984.2 11 bp overlap

ZNF675 1 dataset

Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap

ZNF684 2 datasets

Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap

Motif ES_0h ES_0h-ZNF684_MA1600.2 14 bp overlap

ZNF768 2 datasets

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

Motif ES_0h ES_0h-ZNF768_MA1731.2 9 bp overlap

ZSCAN29 2 datasets

Motif DE_12h DE_12h-ZSCAN29_MA1602.2 11 bp overlap

Motif ES_0h ES_0h-ZSCAN29_MA1602.2 11 bp overlap