chr15 : 90,360,482 – 90,361,151

669 bp 63 TFs 1 linked gene

This 669 bp open chromatin element is linked to ZNF774 and is bound by 63 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ZNF774		8.2 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

63 transcription factors

Ahr::Arnt 2 datasets

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

BRD4 1 dataset

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 239 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF274GAT 319 bp overlap

ChIP BLaER1 ENCFF364PUR 429 bp overlap

ChIP BLaER1 ENCFF460KDD 251 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

ESR1 10 datasets

ChIP Ishikawa ENCSR000BQR.ESR1.Ishikawa 139 bp overlap

ChIP Ishikawa_C2-14 GSE147141.ESR1.Ishikawa_C2-14 210 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 284 bp overlap

ChIP Ishikawa_E2_D538G_clone2 GSE132426.ESR1.Ishikawa_E2_D538G_clone2 303 bp overlap

ChIP Ishikawa_ETV4-KO1_Mili GSE129803.ESR1.Ishikawa_ETV4-KO1_Mili 186 bp overlap

ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 527 bp overlap

ChIP Ishikawa_ETV4-KO2_Rescue GSE129803.ESR1.Ishikawa_ETV4-KO2_Rescue 392 bp overlap

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 512 bp overlap

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 437 bp overlap

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 438 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_E2 GSE94493.ESR1_Y537N.MCF-7_E2 156 bp overlap

EZH2 1 dataset

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 136 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

FOXH1 1 dataset

Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap

GATA6 5 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 303 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 328 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 669 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 514 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 669 bp overlap

HNRNPH1 2 datasets

ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 288 bp overlap

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 274 bp overlap

HOXB4 1 dataset

Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap

Hmx2 1 dataset

Motif DE_12h DE_12h-Hmx2_MA0897.2 15 bp overlap

ISL2 1 dataset

Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 328 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 636 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 669 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

KLF7 1 dataset

Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap

MED1 1 dataset

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 156 bp overlap

NKX2-3 1 dataset

Motif DE_12h DE_12h-NKX2-3_MA0672.2 8 bp overlap

NKX2-8 1 dataset

Motif DE_12h DE_12h-NKX2-8_MA0673.2 8 bp overlap

NKX6-1 1 dataset

Motif DE_12h DE_12h-NKX6-1_MA0674.2 7 bp overlap

NKX6-3 1 dataset

Motif DE_12h DE_12h-NKX6-3_MA1530.2 8 bp overlap

NR2F6 1 dataset

Motif DE_12h DE_12h-NR2F6_MA1539.1 15 bp overlap

Nkx3-2 1 dataset

Motif DE_12h DE_12h-Nkx3-2_MA0122.4 10 bp overlap

Nr1h3::Rxra 2 datasets

Motif DE_12h DE_12h-Nr1h3Rxra_MA0494.2 16 bp overlap

Motif DE_24h DE_24h-Nr1h3Rxra_MA0494.2 16 bp overlap

Nr2e3 1 dataset

Motif DE_12h DE_12h-Nr2e3_MA0164.2 6 bp overlap

PAX1 2 datasets

Motif DE_12h DE_12h-PAX1_MA0779.2 16 bp overlap

Motif DE_24h DE_24h-PAX1_MA0779.2 16 bp overlap

PAX2 2 datasets

Motif DE_12h DE_12h-PAX2_MA0067.3 16 bp overlap

Motif DE_24h DE_24h-PAX2_MA0067.3 16 bp overlap

PAX5 6 datasets

Motif DE_12h DE_12h-PAX5_MA0014.4 8 bp overlap

Motif DE_24h DE_24h-PAX5_MA0014.4 8 bp overlap

ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 295 bp overlap

ChIP GM12878 ENCSR000BHD.PAX5.GM12878 274 bp overlap

ChIP GM12892 ENCSR000BJI.PAX5.GM12892 152 bp overlap

ChIP OCI-Ly7 GSE69558.PAX5.OCI-Ly7 431 bp overlap

PAX8 2 datasets

Motif DE_12h DE_12h-PAX8_MA2094.1 16 bp overlap

Motif DE_24h DE_24h-PAX8_MA2094.1 16 bp overlap

PAX9 2 datasets

Motif DE_12h DE_12h-PAX9_MA0781.2 16 bp overlap

Motif DE_24h DE_24h-PAX9_MA0781.2 16 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 669 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 383 bp overlap

POU6F1 1 dataset

Motif DE_12h DE_12h-POU6F1_MA1549.2 7 bp overlap

POU6F2 1 dataset

Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap

PRDM1 1 dataset

Motif DE_12h DE_12h-PRDM1_MA0508.4 7 bp overlap

PRDM9 1 dataset

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

SIX2 1 dataset

ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 150 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 345 bp overlap

SMAD2-3 3 datasets

ChIP HGrC1_EV GSE138496.SMAD2-3.HGrC1_EV 121 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 669 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 669 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 669 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 669 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 669 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 364 bp overlap

SMARCA4 1 dataset

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 188 bp overlap

SNAI2 1 dataset

Motif DE_12h DE_12h-SNAI2_MA0745.3 8 bp overlap

SP4 1 dataset

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 380 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX19 1 dataset

Motif DE_12h DE_12h-TBX19_MA0804.2 17 bp overlap

TBXT 1 dataset

Motif DE_12h DE_12h-TBXT_MA0009.2 16 bp overlap

TEAD4 1 dataset

ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 190 bp overlap

THRA 2 datasets

Motif DE_12h DE_12h-THRA_MA1969.2 18 bp overlap

Motif DE_24h DE_24h-THRA_MA1969.2 18 bp overlap

TP53 1 dataset

ChIP IMR-90_APO GSE53491.TP53.IMR-90_APO 155 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 588 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 245 bp overlap

ZNF274 1 dataset

Motif DE_12h DE_12h-ZNF274_MA1592.2 12 bp overlap

ZNF354C 1 dataset

Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap

ZNF667 2 datasets

Motif DE_12h DE_12h-ZNF667_MA1984.2 11 bp overlap

Motif DE_24h DE_24h-ZNF667_MA1984.2 11 bp overlap

ZNF75A 1 dataset

Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap

ZNF75D 1 dataset

Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap