chr14 : 65,212,664 – 65,213,594

930 bp 50 TFs 5 linked genes

This 930 bp open chromatin element is linked to 5 target genes and is bound by 50 transcription factors.

Linked Genes

5 genes

Gene	Dist. to TSS	Distance	Link type
MAX	110.7 kb	Distal	Multiome
FUT8	199.5 kb	Distal	Multiome+HiCAR
FNTB	226.3 kb	Distal	Multiome
RAB15	240.9 kb	Distal	Multiome
CHURC1	298.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

50 transcription factors

BRD4 1 dataset

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 266 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 144 bp overlap

CTCF 1 dataset

Motif DE_48h DE_48h-CTCF_MA0139.2 15 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 182 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 654 bp overlap

ChIP DE DE-FOXA2-2 654 bp overlap

GATA2 1 dataset

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 613 bp overlap

ChIP DE DE-GATA4-2 815 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

GATA5 1 dataset

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 557 bp overlap

ChIP DE DE-GATA6-2 930 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 719 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 907 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 904 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 764 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 915 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 930 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 614 bp overlap

Gata3 1 dataset

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

HAND2 1 dataset

Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap

IRF2 1 dataset

Motif DE_60h DE_60h-IRF2_MA0051.2 16 bp overlap

IRF3 1 dataset

Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap

Irf1 1 dataset

Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap

JUN 1 dataset

ChIP DE_D1 S08-DE-d1-JUN-exp1 253 bp overlap

Lhx3 1 dataset

Motif DE_48h DE_48h-Lhx3_MA0135.2 12 bp overlap

MED1 2 datasets

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 102 bp overlap

ChIP hMSC-TERT4_adipocyte-D3 GSE113253.MED1.hMSC-TERT4_adipocyte-D3 184 bp overlap

MITF 3 datasets

ChIP 501-mel GSE137522.MITF.501-mel 243 bp overlap

ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 232 bp overlap

ChIP K-562 ENCSR797SWM.MITF.K-562 207 bp overlap

Mecom 1 dataset

Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap

NFATC3 1 dataset

Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap

Nfatc1 1 dataset

Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap

ONECUT1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 308 bp overlap

POU1F1 1 dataset

Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_48h DE_48h-POU3F4_MA0789.1 9 bp overlap

POU5F1 2 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 216 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 238 bp overlap

POU5F1B 1 dataset

Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 930 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 581 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 586 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 930 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 639 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 930 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 733 bp overlap

SMARCA4 1 dataset

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 184 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 367 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 166 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 383 bp overlap

STAT1::STAT2 1 dataset

Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap

Stat2 1 dataset

Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap

TEAD1 1 dataset

ChIP adipocyte GSE140782.TEAD1.adipocyte 216 bp overlap

TEAD4 6 datasets

ChIP BJ_fibroblast GSE114367.TEAD4.BJ_fibroblast 162 bp overlap

ChIP BJ_fibroblast_CD13-neg GSE114367.TEAD4.BJ_fibroblast_CD13-neg 241 bp overlap

ChIP BJ_fibroblast_CD13-pos GSE114367.TEAD4.BJ_fibroblast_CD13-pos 181 bp overlap

ChIP ESC S26-ESC-d0-TEAD4-exp1 315 bp overlap

ChIP H1 ENCFF778PAX 218 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 205 bp overlap

TRPS1 1 dataset

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

USF1 3 datasets

ChIP H1 ENCFF090WVU 88 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 235 bp overlap

ChIP WTC11 ENCFF699QGS 393 bp overlap

USF2 2 datasets

ChIP H1 ENCFF434EDF 277 bp overlap

ChIP WTC11 ENCFF139JAW 330 bp overlap

ZNF257 1 dataset

Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap

ZNF282 1 dataset

Motif DE_60h DE_60h-ZNF282_MA1154.2 15 bp overlap

ZNF3 1 dataset

ChIP K-562 ENCSR195QFV.ZNF3.K-562 110 bp overlap

ZSCAN30 1 dataset

ChIP HEK293 ENCSR768VNZ.ZSCAN30.HEK293 147 bp overlap