chr12 : 115,370,670 – 115,371,193
523 bp 52 TFs 1 linked gene
This 523 bp open chromatin element is linked to TBX3 and is bound by 52 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TBX3 686.7 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:115,365,670 – 115,376,193
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
52 transcription factors
Source
Cell type
ATRX 2 datasets
ChIP metastatic-neuroblastoma_CHLA90 GSE100148.ATRX.metastatic-neuroblastoma_CHLA90 303 bp overlap
ChIP metastatic-neuroblastoma_SKNFI GSE100148.ATRX.metastatic-neuroblastoma_SKNFI 465 bp overlap
BHLHE22 1 dataset
Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap
BRD4 4 datasets
ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 309 bp overlap
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 399 bp overlap
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 213 bp overlap
ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 215 bp overlap
CHD2 1 dataset
ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 251 bp overlap
CRX 3 datasets
ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 192 bp overlap
ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 375 bp overlap
ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 343 bp overlap
EBF3_P177L 1 dataset
ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 331 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 250 bp overlap
EP300 2 datasets
ChIP SK-N-SH ENCFF829RWA 316 bp overlap
ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 310 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 331 bp overlap
EZH2 1 dataset
ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 349 bp overlap
FOXA2 3 datasets
ChIP DE DE-FOXA2-1 523 bp overlap
ChIP DE DE-FOXA2-2 485 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 230 bp overlap
GATA2 6 datasets
ChIP SH-SY5Y ENCFF485YIB 219 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 510 bp overlap
ChIP SK-N-SH ENCFF764OZD 376 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 313 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 177 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap
GATA3 7 datasets
ChIP BE2C GSE65664.GATA3.BE2C 292 bp overlap
ChIP CLB-Ga GSE90683.GATA3.CLB-Ga 438 bp overlap
ChIP Kelly GSE65664.GATA3.Kelly 309 bp overlap
ChIP SH-SY5Y ENCSR000EXZ.GATA3.SH-SY5Y 417 bp overlap
ChIP SH-SY5Y GSE65664.GATA3.SH-SY5Y 227 bp overlap
ChIP SK-N-BE2-C GSE94822.GATA3.SK-N-BE2-C 204 bp overlap
ChIP SK-N-SH ENCFF040SSB 339 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 523 bp overlap
ChIP DE DE-GATA4-2 523 bp overlap
ChIP foregut GSE117136.GATA4.foregut 349 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 241 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 378 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 523 bp overlap
ChIP DE DE-GATA6-2 523 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 347 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 444 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 310 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 439 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 481 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 408 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 369 bp overlap
ChIP foregut GSE117136.GATA6.foregut 401 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 305 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 348 bp overlap
HAND2 3 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 498 bp overlap
ChIP Kelly GSE94822.HAND2.Kelly 233 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 289 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 256 bp overlap
KDM1A 1 dataset
ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 307 bp overlap
MAML3 2 datasets
ChIP SK-N-SH GSE69119.MAML3.SK-N-SH 482 bp overlap
ChIP SK-N-SH_RA GSE69119.MAML3.SK-N-SH_RA 328 bp overlap
MXI1 1 dataset
ChIP SK-N-SH ENCSR000EIA.MXI1.SK-N-SH 123 bp overlap
MYCN 5 datasets
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 361 bp overlap
ChIP Kelly GSE94822.MYCN.Kelly 238 bp overlap
ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 169 bp overlap
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 430 bp overlap
ChIP NB-1643 GSE94782.MYCN.NB-1643 243 bp overlap
NEUROD1 2 datasets
ChIP D283-Med GSE92582.NEUROD1.D283-Med 238 bp overlap
ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 307 bp overlap
NHLH1 1 dataset
Motif DE_72h DE_72h-NHLH1_MA0048.3 9 bp overlap
Neurod2 1 dataset
Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap
OTX2 1 dataset
ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 288 bp overlap
Olig2 1 dataset
Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap
PBX1 1 dataset
Motif DE_72h DE_72h-PBX1_MA0070.2 9 bp overlap
PHOX2B 1 dataset
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 502 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 523 bp overlap
PPARA 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR602QEJ.PPARA.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 171 bp overlap
Ptf1A 1 dataset
Motif DE_72h DE_72h-Ptf1A_MA1619.2 8 bp overlap
RAD21 1 dataset
ChIP SK-N-SH ENCSR000EHX.RAD21.SK-N-SH 249 bp overlap
RCOR1 2 datasets
ChIP SK-N-SH ENCFF518EXB 343 bp overlap
ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 328 bp overlap
RORB 1 dataset
ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 330 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 386 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 469 bp overlap
SMARCA4 2 datasets
ChIP NGP_ARID1A-mut1 GSE134626.SMARCA4.NGP_ARID1A-mut1 149 bp overlap
ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 523 bp overlap
SMC3 1 dataset
ChIP SK-N-SH ENCFF791WFB 232 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 210 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 437 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 207 bp overlap
TCF4 1 dataset
ChIP SK-N-SH ENCFF270OWF 159 bp overlap
TEAD4 2 datasets
ChIP BE2C GSE84389.TEAD4.BE2C 383 bp overlap
ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 383 bp overlap
TFAP2B 1 dataset
ChIP SK-N-SH ENCFF869XXQ 217 bp overlap
TFAP4 1 dataset
Motif DE_72h DE_72h-TFAP4_MA0691.1 10 bp overlap
TFAP4::FLI1 1 dataset
Motif DE_72h DE_72h-TFAP4FLI1_MA1967.2 14 bp overlap
TSHZ2 2 datasets
ChIP SK-N-SH ENCFF182EBB 381 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 358 bp overlap
Tcf12 1 dataset
Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap
Twist2 1 dataset
Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap
ZNF317 1 dataset
Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap
ZNF44 1 dataset
ChIP HEK293T GSE78099.ZNF44.HEK293T 150 bp overlap
Zfp809 1 dataset
Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap
Huangfu Lab · Publications · Resources · Contact