chr11 : 102,454,369 – 102,454,870

501 bp 56 TFs 2 linked genes

This 501 bp open chromatin element is linked to TMEM123-DT and TMEM123 and is bound by 56 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TMEM123-DT		1.5 kb	Proximal	Proximity
TMEM123		1.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

56 transcription factors

ARNT 1 dataset

ChIP SK-MEL-28 GSE85352.ARNT.SK-MEL-28 316 bp overlap

Atoh1 1 dataset

Motif DE_36h DE_36h-Atoh1_MA1467.3 7 bp overlap

BRD4 1 dataset

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 183 bp overlap

CREBBP 1 dataset

ChIP keratinocyte GSE140991.CREBBP.keratinocyte 79 bp overlap

CTCF 2 datasets

Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap

ChIP keratinocyte ENCSR000DNC.CTCF.keratinocyte 132 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 177 bp overlap

ERF::FOXI1 1 dataset

Motif DE_36h DE_36h-ERFFOXI1_MA1935.2 10 bp overlap

ETV1 1 dataset

Motif DE_36h DE_36h-ETV1_MA0761.3 9 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_36h DE_36h-ETV2FOXI1_MA1942.2 11 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 215 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_Veh-2856 GSE128018.FOXA1.breast-cancer_Veh-2856 122 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_36h DE_36h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_36h DE_36h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_36h DE_36h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_36h DE_36h-FOXO1ELK3_MA1955.2 13 bp overlap

HAND2 1 dataset

Motif DE_36h DE_36h-HAND2_MA1638.2 6 bp overlap

IKZF1 1 dataset

Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 1 dataset

Motif DE_36h DE_36h-Ikzf3_MA1992.2 9 bp overlap

KDM5B 1 dataset

ChIP HCC2157 GSE46055.KDM5B.HCC2157 171 bp overlap

KLF1 2 datasets

ChIP HEK293 ENCFF159QSW 230 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 249 bp overlap

KLF3 1 dataset

ChIP keratinocyte GSE140991.KLF3.keratinocyte 187 bp overlap

KLF6 1 dataset

ChIP PDAC GSE64557.KLF6.PDAC 69 bp overlap

KLF9 1 dataset

ChIP MCF-7 ENCFF618FCM 52 bp overlap

MAX 2 datasets

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 228 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 212 bp overlap

MED1 1 dataset

ChIP NCI-H2171 GSE36354.MED1.NCI-H2171 169 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 382 bp overlap

MYC 1 dataset

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 189 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 336 bp overlap

NEUROD1 6 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 501 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 217 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 255 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 332 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 206 bp overlap

Motif DE_36h DE_36h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_36h DE_36h-NEUROG2_MA1642.2 7 bp overlap

Neurod2 1 dataset

Motif DE_36h DE_36h-Neurod2_MA0668.3 8 bp overlap

OSR2 1 dataset

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 301 bp overlap

PRDM10 1 dataset

ChIP HEK293 ENCFF145WQQ 435 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 220 bp overlap

PROX1 1 dataset

Motif DE_36h DE_36h-PROX1_MA0794.1 12 bp overlap

Ptf1A 1 dataset

Motif DE_36h DE_36h-Ptf1A_MA1618.2 9 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 176 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 186 bp overlap

SMC1A 1 dataset

ChIP primary-epidermal-keratinocyte GSE85526.SMC1A.primary-epidermal-keratinocyte 164 bp overlap

SREBF1 1 dataset

ChIP TE-5 GSE143803.SREBF1.TE-5 441 bp overlap

THRB 1 dataset

Motif DE_36h DE_36h-THRB_MA1576.2 18 bp overlap

TP63 2 datasets

ChIP MCF-10A_DCIS GSE72009.TP63.MCF-10A_DCIS 164 bp overlap

ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 208 bp overlap

YY1 1 dataset

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 206 bp overlap

ZNF12 1 dataset

ChIP HepG2 ENCFF347LSW 93 bp overlap

ZNF175 1 dataset

Motif DE_36h DE_36h-ZNF175_MA2332.1 9 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 272 bp overlap

ZNF394 1 dataset

ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 348 bp overlap

ZNF460 1 dataset

Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap

ZNF708 1 dataset

Motif DE_36h DE_36h-ZNF708_MA1730.2 9 bp overlap

ZNF711 1 dataset

ChIP HEK293T GSE145160.ZNF711.HEK293T 115 bp overlap

ZNF770 1 dataset

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 315 bp overlap

ZNF778 1 dataset

ChIP HEK293 GSE76494.ZNF778.HEK293 192 bp overlap

Zic1::Zic2 1 dataset

Motif DE_36h DE_36h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 1 dataset

Motif DE_36h DE_36h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_36h DE_36h-Zic3_MA0697.3 7 bp overlap