chr1 : 200,665,949 – 200,666,168

219 bp 54 TFs 2 linked genes

This 219 bp open chromatin element is linked to DDX59-AS1 and DDX59 and is bound by 54 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
DDX59-AS1		3.3 kb	Proximal	Proximity
DDX59		3.7 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

54 transcription factors

AR 1 dataset

ChIP LNCaP GSE80256.AR.LNCaP 212 bp overlap

EBF1 1 dataset

ChIP ASC GSE54889.EBF1.ASC 180 bp overlap

EGR1 1 dataset

ChIP macrophage_D1 GSE136216.EGR1.macrophage_D1 131 bp overlap

EP300 1 dataset

ChIP tibial nerve ENCFF346AYA 219 bp overlap

ERF::FIGLA 1 dataset

Motif DE_12h DE_12h-ERFFIGLA_MA1934.2 13 bp overlap

ERG 1 dataset

ChIP HUVEC-C GSE128382.ERG.HUVEC-C 219 bp overlap

ETS1 1 dataset

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 136 bp overlap

FLI1 1 dataset

ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 169 bp overlap

FOS 1 dataset

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 150 bp overlap

FOXA1 2 datasets

ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 96 bp overlap

ChIP T-47D_shRNF2_8h GSE137579.FOXA1.T-47D_shRNF2_8h 91 bp overlap

FOXA2 6 datasets

ChIP BJ1-hTERT GSE90454.FOXA2.BJ1-hTERT 219 bp overlap

ChIP BJ1-hTERT_CDT1 GSE92491.FOXA2.BJ1-hTERT_CDT1 140 bp overlap

ChIP BJ1-hTERT_Mimo GSE92491.FOXA2.BJ1-hTERT_Mimo 219 bp overlap

ChIP DE DE-FOXA2-2 154 bp overlap

ChIP KerCT GSE90454.FOXA2.KerCT 70 bp overlap

ChIP KerCT GSE90454.FOXA2.KerCT 95 bp overlap

GATA4 1 dataset

ChIP BJ1-hTERT GSE92491.GATA4.BJ1-hTERT 52 bp overlap

GATA6 4 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 219 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 194 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 219 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 189 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

Hic1 1 dataset

Motif DE_12h DE_12h-Hic1_MA0739.2 8 bp overlap

IKZF1 5 datasets

ChIP BCR-ABL1_LAX2 GSE58825.IKZF1.BCR-ABL1_LAX2 206 bp overlap

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

ChIP K-562 ENCSR395HWC.IKZF1.K-562 219 bp overlap

ChIP K562 ENCFF348IBL 219 bp overlap

ChIP K562 ENCFF771OHZ 219 bp overlap

JUNB 1 dataset

ChIP MCF10A-Er-Src_EtOH GSE115597.JUNB.MCF10A-Er-Src_EtOH 123 bp overlap

LIN54 1 dataset

Motif DE_12h DE_12h-LIN54_MA0619.2 7 bp overlap

MED1 2 datasets

ChIP SGBS GSE64233.MED1.SGBS 215 bp overlap

ChIP hMSC-TERT4_D7 GSE104537.MED1.hMSC-TERT4_D7 154 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 219 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 219 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 219 bp overlap

ChIP hESC GSE18292.NANOG.hESC 175 bp overlap

NFIA 1 dataset

Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap

NFIX 1 dataset

Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap

NR3C1 1 dataset

ChIP SUP-B15_DEX GSE107584.NR3C1.SUP-B15_DEX 219 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU5F1 13 datasets

ChIP GM23338 ENCFF333SNB 219 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 219 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 219 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 219 bp overlap

ChIP OSKM GSE81899.POU5F1.OSKM 219 bp overlap

ChIP OSvKM GSE81899.POU5F1.OSvKM 205 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 138 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 219 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 219 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 219 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 198 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR362VCG.POU5F1.neuron_bipolar_doxy_4d 167 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

PSIP1 1 dataset

ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 119 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 1 dataset

ChIP HAP1 GSE152721.RAD21.HAP1 142 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

RELA 2 datasets

ChIP SGBS GSE64233.RELA.SGBS 199 bp overlap

ChIP aortic-endothelial-cell_IL1B_D4 GSE139377.RELA.aortic-endothelial-cell_IL1B_D4 209 bp overlap

REST 1 dataset

ChIP K-562 ENCSR000BMW.REST.K-562 101 bp overlap

SMARCA2 2 datasets

ChIP NPC_K755R-pos GSE122631.SMARCA2.NPC_K755R-pos 105 bp overlap

ChIP NPC_K755R-siAP GSE122631.SMARCA2.NPC_K755R-siAP 219 bp overlap

SMARCA4 3 datasets

ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 167 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 219 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 219 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 197 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 219 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 219 bp overlap

SOX2 3 datasets

ChIP RENVM GSE49404.SOX2.RENVM 151 bp overlap

ChIP hESC GSE18292.SOX2.hESC 103 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 219 bp overlap

STAT1 1 dataset

Motif DE_12h DE_12h-STAT1_MA0137.4 9 bp overlap

STAT3 1 dataset

Motif DE_12h DE_12h-STAT3_MA0144.3 9 bp overlap

Stat4 1 dataset

Motif DE_12h DE_12h-Stat4_MA0518.2 10 bp overlap

Stat5a 1 dataset

Motif DE_12h DE_12h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5aStat5b_MA0519.2 9 bp overlap

Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5b_MA1625.2 9 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 219 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TCF21 1 dataset

ChIP HCASMC GSE124011.TCF21.HCASMC 219 bp overlap

TFAP4::ETV1 1 dataset

Motif DE_12h DE_12h-TFAP4ETV1_MA1966.2 13 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap

ZNF143 1 dataset

ChIP WA09 GSE105028.ZNF143.WA09 200 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 208 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 214 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 168 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap