chr11:32,441,013–32,441,260

chr11 : 32,441,013 – 32,441,260

247 bp 49 TFs 6 linked genes

This 247 bp open chromatin element is linked to 6 target genes and is bound by 49 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000276530		1.9 kb	Proximal	Proximity
ENSG00000278045		4.2 kb	Proximal	Proximity
ENSG00000273677		4.7 kb	Proximal	Proximity
ENSG00000278822		5.3 kb	Proximal	Proximity
WT1-AS		5.4 kb	Proximal	Proximity
WT1		5.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

49 transcription factors

BCL11A 1 dataset

Motif DE_24h DE_24h-BCL11A_MA2324.1 7 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 207 bp overlap

CTCF 2 datasets

ChIP endodermal cell ENCFF471YCZ 247 bp overlap

ChIP epithelial_kidney ENCSR000DVH.CTCF.epithelial_kidney 191 bp overlap

Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

DPRX 2 datasets

Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap

Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap

Dmbx1 2 datasets

Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap

Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 143 bp overlap

EZH2 13 datasets

ChIP A673 ENCFF790MVL 241 bp overlap

ChIP H1 ENCFF232NZA 247 bp overlap

ChIP H1 ENCFF232NZA 247 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 247 bp overlap

ChIP dermal-fibroblast_Preneoplastic GSE126396.EZH2.dermal-fibroblast_Preneoplastic 230 bp overlap

ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 189 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 165 bp overlap

ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 167 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 245 bp overlap

ChIP keratinocyte ENCFF070STK 247 bp overlap

ChIP keratinocyte ENCFF070STK 247 bp overlap

ChIP keratinocyte ENCSR000ARK.EZH2.keratinocyte 247 bp overlap

ChIP neural progenitor cell ENCFF472NFV 247 bp overlap

EZH2_phosphoT487 1 dataset

ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 231 bp overlap

FOXH1 1 dataset

Motif DE_24h DE_24h-FOXH1_MA0479.2 8 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 222 bp overlap

ChIP DE DE-GATA4-2 247 bp overlap

GATA5 2 datasets

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-2 247 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 199 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 247 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 247 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 247 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 247 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 247 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 247 bp overlap

Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

GSC2 2 datasets

Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR000BMG.HDAC2.K-562 116 bp overlap

HOXB4 1 dataset

Motif DE_24h DE_24h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_24h DE_24h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_24h DE_24h-HOXD4_MA1507.2 6 bp overlap

JARID2 5 datasets

ChIP AMIPS8 GSE48516.JARID2.AMIPS8 136 bp overlap

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 247 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 247 bp overlap

ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 226 bp overlap

ChIP UTEIPS7 GSE48516.JARID2.UTEIPS7 247 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 157 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 161 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 232 bp overlap

ChIP P493-6_MST-312 GSE77061.MYC.P493-6_MST-312 153 bp overlap

ONECUT1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 82 bp overlap

OTX1 2 datasets

Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

OVOL1 2 datasets

Motif DE_48h DE_48h-OVOL1_MA1544.2 10 bp overlap

Motif DE_60h DE_60h-OVOL1_MA1544.2 10 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 211 bp overlap

PHF19 1 dataset

ChIP DU145_CTR GSE135623.PHF19.DU145_CTR 247 bp overlap

PITX1 2 datasets

Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

PITX3 2 datasets

Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 229 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 230 bp overlap

RAD21 1 dataset

ChIP H1 ENCFF698EWO 219 bp overlap

RHOXF1 2 datasets

Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

RING1 1 dataset

ChIP SYO-1_shCt GSE139053.RING1.SYO-1_shCt 186 bp overlap

RNF2 3 datasets

ChIP H1 ENCFF239FFS 235 bp overlap

ChIP HMELBRAF_OVER GSE51929.RNF2.HMELBRAF_OVER 174 bp overlap

ChIP WA01 GSE104690.RNF2.WA01 207 bp overlap

SMAD2 4 datasets

ChIP endoderm GSE29422.SMAD2.endoderm 247 bp overlap

ChIP hESC GSE29422.SMAD2.hESC 220 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 247 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 247 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 247 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 247 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 247 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 247 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 247 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 247 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 247 bp overlap

SMAD3 3 datasets

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 177 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 156 bp overlap

ChIP hESC GSE29422.SMAD3.hESC 235 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 247 bp overlap

SMARCC1 2 datasets

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 247 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 122 bp overlap

SUZ12 3 datasets

ChIP Aska-SS GSE108025.SUZ12.Aska-SS 247 bp overlap

ChIP H1 ENCFF881NFR 247 bp overlap

ChIP NT2-D1 ENCSR000EXH.SUZ12.NT2-D1 116 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 194 bp overlap

TCF7L2 1 dataset

ChIP CD34_PROG_BIO GSE29194.TCF7L2.CD34_PROG_BIO 156 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 247 bp overlap

ZNF317 1 dataset

Motif DE_24h DE_24h-ZNF317_MA1593.2 8 bp overlap

ZNF75A 2 datasets

Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap

Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap