chr10 : 113,078,444 – 113,078,930
486 bp 63 TFs 1 linked gene
This 486 bp open chromatin element is linked to TCF7L2 and is bound by 63 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TCF7L2 128.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr10:113,073,444 – 113,083,930
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
63 transcription factors
Source
Cell type
ARID1B 1 dataset
ChIP K-562 ENCSR822CCM.ARID1B.K-562 207 bp overlap
Ahr::Arnt 2 datasets
Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 237 bp overlap
ChIP K562 ENCFF673OEZ 328 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 103 bp overlap
CTCF 2 datasets
Motif DE_60h DE_60h-CTCF_MA1929.2 31 bp overlap
Motif DE_72h DE_72h-CTCF_MA1929.2 31 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF274GAT 232 bp overlap
ChIP BLaER1 ENCFF364PUR 267 bp overlap
Crx 6 datasets
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 261 bp overlap
EP300 1 dataset
ChIP K562 ENCFF226VMS 317 bp overlap
FEZF1 1 dataset
ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 239 bp overlap
FEZF2 1 dataset
Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap
FOSL2 1 dataset
Motif DE_60h DE_60h-FOSL2_MA0478.2 10 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 405 bp overlap
ChIP DE DE-FOXA2-2 446 bp overlap
FOXO1-PAX3 1 dataset
ChIP RH4_Entinostat-6H GSE116344.FOXO1-PAX3.RH4_Entinostat-6H 272 bp overlap
GATA1 3 datasets
ChIP K-562 GSE107726.GATA1.K-562 177 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 129 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 138 bp overlap
GATA2 5 datasets
ChIP K-562 ENCSR000DKA.GATA2.K-562 239 bp overlap
ChIP K-562 ENCSR000EWG.GATA2.K-562 132 bp overlap
ChIP dermal-fibroblast GSE51025.GATA2.dermal-fibroblast 190 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 201 bp overlap
ChIP hiPSC_SLC9ebs GSE107639.GATA2.hiPSC_SLC9ebs 189 bp overlap
GATA3_Nter 1 dataset
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 254 bp overlap
GATA4 6 datasets
ChIP A-549 GSE85002.GATA4.A-549 224 bp overlap
ChIP DE DE-GATA4-1 453 bp overlap
ChIP DE DE-GATA4-2 486 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 355 bp overlap
ChIP foregut GSE117136.GATA4.foregut 441 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 409 bp overlap
GATA5 3 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 18 datasets
ChIP AGS GSE51705.GATA6.AGS 178 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 198 bp overlap
ChIP DE DE-GATA6-1 483 bp overlap
ChIP DE DE-GATA6-2 486 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 486 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 482 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 486 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 486 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 467 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 486 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 449 bp overlap
ChIP foregut GSE117136.GATA6.foregut 436 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 390 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 368 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 287 bp overlap
GFI1B 1 dataset
ChIP K-562 ENCSR509GDT.GFI1B.K-562 159 bp overlap
GSC 6 datasets
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 6 datasets
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gata3 3 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HDAC1 2 datasets
ChIP K-562 ENCSR387UWP.HDAC1.K-562 275 bp overlap
ChIP K562 ENCFF968WBH 403 bp overlap
HDAC2 4 datasets
ChIP K-562 ENCSR893WSB.HDAC2.K-562 297 bp overlap
ChIP K562 ENCFF744ALD 333 bp overlap
ChIP K562 ENCFF744ALD 129 bp overlap
ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 449 bp overlap
IKZF1 1 dataset
ChIP K-562 ENCSR395HWC.IKZF1.K-562 276 bp overlap
Irf1 2 datasets
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 385 bp overlap
KDM1A 3 datasets
ChIP K-562 ENCSR360HRA.KDM1A.K-562 434 bp overlap
ChIP K-562 ENCSR908CMW.KDM1A.K-562 376 bp overlap
ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 166 bp overlap
MGA::EVX1 2 datasets
Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap
NFE2 3 datasets
ChIP K-562 ENCSR000FCC.NFE2.K-562 109 bp overlap
ChIP K562 ENCFF047YKA 326 bp overlap
ChIP K562 ENCFF163BSI 224 bp overlap
NFYB 1 dataset
ChIP K-562 ENCSR000EGQ.NFYB.K-562 111 bp overlap
NR2F1 1 dataset
ChIP K-562 ENCSR970NKQ.NR2F1.K-562 346 bp overlap
NR2F6 1 dataset
ChIP HepG2 ENCFF429VKC 171 bp overlap
OTX1 6 datasets
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
OTX2 1 dataset
Motif DE_60h DE_60h-OTX2_MA0712.3 7 bp overlap
PAF1 1 dataset
ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 413 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH4 GSE140115.PAX3-FOXO1.RH4 360 bp overlap
PITX1 6 datasets
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX2 3 datasets
Motif DE_36h DE_36h-PITX2_MA1547.2 8 bp overlap
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap
PITX3 6 datasets
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
RBM25 1 dataset
ChIP K562 ENCFF248CGR 205 bp overlap
RCOR1 1 dataset
ChIP K562 ENCFF216EEJ 293 bp overlap
RHOXF1 6 datasets
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
SETDB1 1 dataset
ChIP U2OS ENCSR000EYD.SETDB1.U2OS 276 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 133 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 446 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 322 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 368 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 327 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 330 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 342 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 410 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 409 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 250 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 218 bp overlap
SUPT5H 1 dataset
ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 440 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 215 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 196 bp overlap
TCF12 1 dataset
ChIP K-562 ENCSR744WOO.TCF12.K-562 195 bp overlap
TRPS1 3 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ZNF121 6 datasets
ChIP HEK293 ENCFF839FUF 104 bp overlap
ChIP HEK293 ENCSR224QDY.ZNF121.HEK293 220 bp overlap
ChIP HEK293 GSE76494.ZNF121.HEK293 123 bp overlap
ChIP Hep-G2 ENCSR945QEW.ZNF121.Hep-G2 174 bp overlap
ChIP HepG2 ENCFF343YSL 250 bp overlap
ChIP WTC11 ENCFF291API 205 bp overlap
ZNF135 1 dataset
Motif DE_60h DE_60h-ZNF135_MA1587.1 14 bp overlap
ZNF384 1 dataset
ChIP K-562 ENCSR000EFP.ZNF384.K-562 112 bp overlap
ZNF460 1 dataset
Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap
ZNF701 1 dataset
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
ZNF750 1 dataset
ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 251 bp overlap
ZNF85 3 datasets
Motif DE_36h DE_36h-ZNF85_MA1720.2 12 bp overlap
Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap
Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap
Zfp809 1 dataset
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
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