chr8:93,952,630–93,953,256

chr8 : 93,952,630 – 93,953,256

626 bp 63 TFs 5 linked genes

This 626 bp open chromatin element is linked to 5 target genes and is bound by 63 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PDP1		35.3 kb	Distal	Multiome
TMEM67		198.1 kb	Distal	Multiome
RBM12B		212.0 kb	Distal	Multiome+HiCAR
CIBAR1		252.5 kb	Distal	Multiome
RUNX1T1		1857.4 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

63 transcription factors

CTCF 10 datasets

ChIP GM23338 ENCFF772DML 56 bp overlap

ChIP H9 ENCFF152GTF 279 bp overlap

ChIP MCF-7 ENCFF844STM 188 bp overlap

ChIP MCF-7 ENCFF954TUV 188 bp overlap

ChIP Panc1 ENCFF056JQX 375 bp overlap

ChIP WERI-Rb-1 ENCFF349QKF 147 bp overlap

ChIP endodermal cell ENCFF471YCZ 250 bp overlap

ChIP parathyroid adenoma ENCFF173NJK 287 bp overlap

ChIP parathyroid adenoma ENCFF173NJK 421 bp overlap

ChIP right atrium auricular region ENCFF696NTN 362 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF274GAT 104 bp overlap

ChIP BLaER1 ENCFF460KDD 107 bp overlap

Dmrt1 2 datasets

Motif DE_12h DE_12h-Dmrt1_MA1603.2 9 bp overlap

Motif DE_72h DE_72h-Dmrt1_MA1603.2 9 bp overlap

FOXA1 13 datasets

Motif DE_12h DE_12h-FOXA1_MA0148.5 8 bp overlap

Motif DE_72h DE_72h-FOXA1_MA0148.5 8 bp overlap

ChIP HepG2 ENCFF207NVJ 203 bp overlap

ChIP HepG2 ENCFF361KNY 285 bp overlap

ChIP HepG2 ENCFF740VZW 168 bp overlap

ChIP MCF-7 GSE59530.FOXA1.MCF-7 141 bp overlap

ChIP MCF-7_E2 GSE59530.FOXA1.MCF-7_E2 126 bp overlap

ChIP MCF-7_E2_TNF GSE59530.FOXA1.MCF-7_E2_TNF 142 bp overlap

ChIP MCF-7_TNF GSE59530.FOXA1.MCF-7_TNF 136 bp overlap

ChIP MCF-7_shNR2F2 GSE132432.FOXA1.MCF-7_shNR2F2 317 bp overlap

ChIP NCI-H3122 GSE39998.FOXA1.NCI-H3122 152 bp overlap

ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 163 bp overlap

ChIP breast_tumor_Male_14 GSE104399.FOXA1.breast_tumor_Male_14 278 bp overlap

FOXA2 9 datasets

ChIP DE DE-FOXA2-1 491 bp overlap

ChIP DE DE-FOXA2-2 515 bp overlap

Motif DE_12h DE_12h-FOXA2_MA0047.4 8 bp overlap

Motif DE_72h DE_72h-FOXA2_MA0047.4 8 bp overlap

ChIP HepG2 ENCFF533COJ 136 bp overlap

ChIP HepG2 ENCFF570ABM 290 bp overlap

ChIP HepG2 ENCFF894AYY 144 bp overlap

ChIP colorectal-cancer_type-C GSE106921.FOXA2.colorectal-cancer_type-C 219 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 229 bp overlap

FOXA3 3 datasets

Motif DE_12h DE_12h-FOXA3_MA1683.2 7 bp overlap

Motif DE_72h DE_72h-FOXA3_MA1683.2 7 bp overlap

ChIP HepG2 ENCFF005KGL 361 bp overlap

FOXB1 2 datasets

Motif DE_12h DE_12h-FOXB1_MA0845.1 11 bp overlap

Motif DE_72h DE_72h-FOXB1_MA0845.1 11 bp overlap

FOXC1 2 datasets

Motif DE_12h DE_12h-FOXC1_MA0032.2 11 bp overlap

Motif DE_72h DE_72h-FOXC1_MA0032.2 11 bp overlap

FOXC2 2 datasets

Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap

Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap

FOXD1 2 datasets

Motif DE_12h DE_12h-FOXD1_MA0031.2 7 bp overlap

Motif DE_72h DE_72h-FOXD1_MA0031.2 7 bp overlap

FOXD2 2 datasets

Motif DE_12h DE_12h-FOXD2_MA0847.4 11 bp overlap

Motif DE_72h DE_72h-FOXD2_MA0847.4 11 bp overlap

FOXD3 2 datasets

Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap

Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap

FOXE1 2 datasets

Motif DE_12h DE_12h-FOXE1_MA1487.3 12 bp overlap

Motif DE_72h DE_72h-FOXE1_MA1487.3 12 bp overlap

FOXG1 2 datasets

Motif DE_12h DE_12h-FOXG1_MA0613.1 8 bp overlap

Motif DE_72h DE_72h-FOXG1_MA0613.1 8 bp overlap

FOXI1 2 datasets

Motif DE_12h DE_12h-FOXI1_MA0042.2 7 bp overlap

Motif DE_72h DE_72h-FOXI1_MA0042.2 7 bp overlap

FOXK1 2 datasets

Motif DE_12h DE_12h-FOXK1_MA0852.3 7 bp overlap

Motif DE_72h DE_72h-FOXK1_MA0852.3 7 bp overlap

FOXK2 2 datasets

Motif DE_12h DE_12h-FOXK2_MA1103.3 7 bp overlap

Motif DE_72h DE_72h-FOXK2_MA1103.3 7 bp overlap

FOXL1 2 datasets

Motif DE_12h DE_12h-FOXL1_MA0033.2 7 bp overlap

Motif DE_72h DE_72h-FOXL1_MA0033.2 7 bp overlap

FOXN3 2 datasets

Motif DE_12h DE_12h-FOXN3_MA1489.1 8 bp overlap

Motif DE_72h DE_72h-FOXN3_MA1489.1 8 bp overlap

FOXO4 2 datasets

Motif DE_12h DE_12h-FOXO4_MA0848.1 7 bp overlap

Motif DE_72h DE_72h-FOXO4_MA0848.1 7 bp overlap

FOXO6 2 datasets

Motif DE_12h DE_12h-FOXO6_MA0849.1 7 bp overlap

Motif DE_72h DE_72h-FOXO6_MA0849.1 7 bp overlap

FOXP1 2 datasets

Motif DE_12h DE_12h-FOXP1_MA0481.4 7 bp overlap

Motif DE_72h DE_72h-FOXP1_MA0481.4 7 bp overlap

FOXP2 2 datasets

Motif DE_12h DE_12h-FOXP2_MA0593.2 9 bp overlap

Motif DE_72h DE_72h-FOXP2_MA0593.2 9 bp overlap

FOXP3 2 datasets

Motif DE_12h DE_12h-FOXP3_MA0850.1 7 bp overlap

Motif DE_72h DE_72h-FOXP3_MA0850.1 7 bp overlap

FOXP4 2 datasets

Motif DE_12h DE_12h-FOXP4_MA2117.1 7 bp overlap

Motif DE_72h DE_72h-FOXP4_MA2117.1 7 bp overlap

FOXS1 2 datasets

Motif DE_12h DE_12h-FOXS1_MA2118.1 8 bp overlap

Motif DE_72h DE_72h-FOXS1_MA2118.1 8 bp overlap

Foxf1 2 datasets

Motif DE_12h DE_12h-Foxf1_MA1606.2 7 bp overlap

Motif DE_72h DE_72h-Foxf1_MA1606.2 7 bp overlap

Foxj2 2 datasets

Motif DE_12h DE_12h-Foxj2_MA0614.1 8 bp overlap

Motif DE_72h DE_72h-Foxj2_MA0614.1 8 bp overlap

Foxj3 2 datasets

Motif DE_12h DE_12h-Foxj3_MA0851.2 9 bp overlap

Motif DE_72h DE_72h-Foxj3_MA0851.2 9 bp overlap

Foxl2 2 datasets

Motif DE_12h DE_12h-Foxl2_MA1607.2 10 bp overlap

Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap

Foxo1 2 datasets

Motif DE_12h DE_12h-Foxo1_MA0480.3 7 bp overlap

Motif DE_72h DE_72h-Foxo1_MA0480.3 7 bp overlap

Foxo3 2 datasets

Motif DE_12h DE_12h-Foxo3_MA0157.4 7 bp overlap

Motif DE_72h DE_72h-Foxo3_MA0157.4 7 bp overlap

Foxq1 2 datasets

Motif DE_12h DE_12h-Foxq1_MA0040.2 10 bp overlap

Motif DE_72h DE_72h-Foxq1_MA0040.2 10 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 289 bp overlap

ChIP DE DE-GATA4-2 352 bp overlap

GATA6 2 datasets

ChIP DE DE-GATA6-2 454 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 331 bp overlap

Hand1::Tcf3 2 datasets

Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap

Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap

Motif DE_12h DE_12h-Hic1_MA0739.2 8 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 138 bp overlap

Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap

Motif DE_72h DE_72h-MYB_MA0100.4 6 bp overlap

ChIP SEM GSE117864.MYB.SEM 172 bp overlap

NR1I3 2 datasets

Motif DE_12h DE_12h-NR1I3_MA1534.2 8 bp overlap

Motif DE_72h DE_72h-NR1I3_MA1534.2 8 bp overlap

ChIP HEK293 ENCFF875BDB 178 bp overlap

PAX5 2 datasets

ChIP GM12878 ENCSR000BHD.PAX5.GM12878 123 bp overlap

ChIP NALM-6 GSE126300.PAX5.NALM-6 199 bp overlap

PITX1 1 dataset

ChIP HepG2 ENCFF468QTQ 413 bp overlap

POU5F1 3 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

Motif DE_72h DE_72h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 273 bp overlap

RAD21 2 datasets

ChIP H1 ENCFF698EWO 203 bp overlap

ChIP H1 ENCFF967OJF 162 bp overlap

RBPJ 2 datasets

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap

SMAD2 2 datasets

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 449 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 365 bp overlap

SOX10 2 datasets

Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 333 bp overlap

SOX4 2 datasets

Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

STAT1 2 datasets

Motif DE_12h DE_12h-STAT1_MA0137.4 9 bp overlap

Motif DE_72h DE_72h-STAT1_MA0137.4 9 bp overlap

STAT3 3 datasets

Motif DE_12h DE_12h-STAT3_MA0144.3 9 bp overlap

Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap

ChIP NCI-H358 GSE79707.STAT3.NCI-H358 245 bp overlap

Sox11 2 datasets

Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

Stat4 2 datasets

Motif DE_12h DE_12h-Stat4_MA0518.2 10 bp overlap

Motif DE_72h DE_72h-Stat4_MA0518.2 10 bp overlap

Stat5b 2 datasets

Motif DE_12h DE_12h-Stat5b_MA1625.2 9 bp overlap

Motif DE_72h DE_72h-Stat5b_MA1625.2 9 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 202 bp overlap

ChIP H1 ENCFF524BTL 295 bp overlap

ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 237 bp overlap

ChIP Ishikawa ENCFF505XQX 332 bp overlap

ZIC2 2 datasets

ChIP HEK293 ENCFF033NQQ 181 bp overlap

ChIP HEK293 ENCFF033NQQ 148 bp overlap

ZNF281 3 datasets

ChIP HepG2 ENCFF585QNU 214 bp overlap

ChIP WTC11 ENCFF551GAV 331 bp overlap

ChIP WTC11 ENCFF551GAV 127 bp overlap

ZNF574 4 datasets

Motif DE_12h DE_12h-ZNF574_MA1982.2 14 bp overlap

Motif DE_12h DE_12h-ZNF574_MA1982.2 14 bp overlap

Motif DE_72h DE_72h-ZNF574_MA1982.2 14 bp overlap

Motif DE_72h DE_72h-ZNF574_MA1982.2 14 bp overlap

ZNF576 1 dataset

ChIP HepG2 ENCFF157BAG 266 bp overlap

Zfp809 2 datasets

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap