Enables phospholipid binding activity. Involved in several processes, including inner mitochondrial membrane organization; limb morphogenesis; and membrane tubulation. Located in several cellular components, including centriole; ciliary base; and mitochondrial crista. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CIBAR1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CIBAR1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CIBAR1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr8:92,071,291–92,071,975 | 1628.9 kb | Distal (>10kb) Multiome HiCAR | 207 | |
| chr8:92,146,581–92,147,618 | 1553.6 kb | Distal (>10kb) Multiome HiCAR | 76 | |
| chr8:92,148,238–92,149,315 | 1551.7 kb | Distal (>10kb) Multiome HiCAR | 243 | |
| chr8:93,582,408–93,584,018 | 116.8 kb | Distal (>10kb) Multiome | 191 | |
| chr8:93,693,728–93,694,359 | 6.2 kb | Proximal (<10kb) | 193 | |
| chr8:93,696,294–93,696,444 | 4.1 kb | Proximal (<10kb) | 38 | |
| chr8:93,696,568–93,696,796 | 3.8 kb | Proximal (<10kb) | 60 | |
| chr8:93,698,442–93,698,810 | 1.7 kb | Proximal (<10kb) | 133 | |
| chr8:93,699,869–93,701,509 | 28 bp | At TSS Multiome | 609 | |
| chr8:93,740,245–93,741,472 | 40.5 kb | Distal (>10kb) Multiome | 876 | |
| chr8:93,754,676–93,755,350 | 54.3 kb | Distal (>10kb) Multiome | 573 | |
| chr8:93,915,949–93,918,134 | 216.2 kb | Distal (>10kb) Multiome | 821 | |
| chr8:93,943,280–93,944,641 | 243.5 kb | Distal (>10kb) Multiome | 354 | |
| chr8:93,952,630–93,953,256 | 252.5 kb | Distal (>10kb) Multiome | 63 | |
| chr8:93,991,163–93,992,088 | 291.1 kb | Distal (>10kb) Multiome | 561 |
Genomic view of the CIBAR1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.