chr7 : 67,583,213 – 67,584,089
876 bp 67 TFs 2 linked genes
This 876 bp open chromatin element is linked to STAG3L4 and PMS2P4 and is bound by 67 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
STAG3L4 281.0 kb Distal Multiome
PMS2P4 281.2 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr7:67,578,213 – 67,589,089
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
67 transcription factors
Source
Cell type
Bcl11B 2 datasets
Motif DE_24h DE_24h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_48h DE_48h-Bcl11B_MA1989.2 9 bp overlap
Dux 2 datasets
Motif DE_24h DE_24h-Dux_MA0611.3 11 bp overlap
Motif DE_36h DE_36h-Dux_MA0611.3 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 258 bp overlap
ERF::FOXO1 3 datasets
Motif DE_24h DE_24h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_36h DE_36h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_48h DE_48h-ERFFOXO1_MA1936.2 12 bp overlap
ETV2::FIGLA 2 datasets
Motif DE_24h DE_24h-ETV2FIGLA_MA1941.2 13 bp overlap
Motif DE_36h DE_36h-ETV2FIGLA_MA1941.2 13 bp overlap
ETV5::FIGLA 2 datasets
Motif DE_24h DE_24h-ETV5FIGLA_MA1945.2 14 bp overlap
Motif DE_36h DE_36h-ETV5FIGLA_MA1945.2 14 bp overlap
FOXB1 3 datasets
Motif DE_24h DE_24h-FOXB1_MA0845.1 11 bp overlap
Motif DE_36h DE_36h-FOXB1_MA0845.1 11 bp overlap
Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap
FOXO1::ELK3 2 datasets
Motif DE_24h DE_24h-FOXO1ELK3_MA1955.2 13 bp overlap
Motif DE_36h DE_36h-FOXO1ELK3_MA1955.2 13 bp overlap
GATA5 3 datasets
Motif DE_24h DE_24h-GATA5_MA0766.3 8 bp overlap
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
GATA6 10 datasets
Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 619 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 692 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 572 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 527 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 804 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 725 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 269 bp overlap
Gata3 3 datasets
Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Gfi1B 2 datasets
Motif DE_24h DE_24h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_36h DE_36h-Gfi1B_MA0483.2 10 bp overlap
HOXB4 3 datasets
Motif DE_24h DE_24h-HOXB4_MA1499.2 6 bp overlap
Motif DE_36h DE_36h-HOXB4_MA1499.2 6 bp overlap
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
HOXC4 3 datasets
Motif DE_24h DE_24h-HOXC4_MA1504.2 6 bp overlap
Motif DE_36h DE_36h-HOXC4_MA1504.2 6 bp overlap
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
HOXD4 3 datasets
Motif DE_24h DE_24h-HOXD4_MA1507.2 6 bp overlap
Motif DE_36h DE_36h-HOXD4_MA1507.2 6 bp overlap
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
Hand1::Tcf3 3 datasets
Motif DE_24h DE_24h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_36h DE_36h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
INSM1 2 datasets
Motif DE_24h DE_24h-INSM1_MA0155.1 12 bp overlap
Motif DE_36h DE_36h-INSM1_MA0155.1 12 bp overlap
JUN 4 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 639 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 476 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 508 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 622 bp overlap
KDM1A 1 dataset
ChIP SH-SY5Y_B0_SHLSD18A GSE58258.KDM1A.SH-SY5Y_B0_SHLSD18A 70 bp overlap
KDM3A 1 dataset
ChIP 22Rv1_shKDM3A GSE109748.KDM3A.22Rv1_shKDM3A 66 bp overlap
KLF4 2 datasets
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap
MEIS1 3 datasets
Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
MXI1 4 datasets
Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap
Motif DE_24h DE_24h-MXI1_MA1108.3 6 bp overlap
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
NFE2 4 datasets
Motif DE_12h DE_12h-NFE2_MA0841.2 10 bp overlap
Motif DE_24h DE_24h-NFE2_MA0841.2 10 bp overlap
Motif DE_36h DE_36h-NFE2_MA0841.2 10 bp overlap
Motif DE_48h DE_48h-NFE2_MA0841.2 10 bp overlap
NFYA 2 datasets
Motif DE_24h DE_24h-NFYA_MA0060.4 8 bp overlap
Motif DE_36h DE_36h-NFYA_MA0060.4 8 bp overlap
NFYB 3 datasets
Motif DE_24h DE_24h-NFYB_MA0502.3 9 bp overlap
Motif DE_36h DE_36h-NFYB_MA0502.3 9 bp overlap
Motif DE_48h DE_48h-NFYB_MA0502.3 9 bp overlap
NFYC 2 datasets
Motif DE_24h DE_24h-NFYC_MA1644.2 7 bp overlap
Motif DE_36h DE_36h-NFYC_MA1644.2 7 bp overlap
NR3C1 1 dataset
ChIP HeLa-B2_GRKD_TA_TNFA GSE24518.NR3C1.HeLa-B2_GRKD_TA_TNFA 98 bp overlap
NR4A1 3 datasets
Motif DE_24h DE_24h-NR4A1_MA1112.3 8 bp overlap
Motif DE_36h DE_36h-NR4A1_MA1112.3 8 bp overlap
Motif DE_48h DE_48h-NR4A1_MA1112.3 8 bp overlap
NR4A2 3 datasets
Motif DE_24h DE_24h-NR4A2_MA0160.3 8 bp overlap
Motif DE_36h DE_36h-NR4A2_MA0160.3 8 bp overlap
Motif DE_48h DE_48h-NR4A2_MA0160.3 8 bp overlap
NRL 2 datasets
Motif DE_24h DE_24h-NRL_MA0842.3 12 bp overlap
Motif DE_36h DE_36h-NRL_MA0842.3 12 bp overlap
ONECUT1 4 datasets
Motif DE_12h DE_12h-ONECUT1_MA0679.3 9 bp overlap
Motif DE_24h DE_24h-ONECUT1_MA0679.3 9 bp overlap
Motif DE_36h DE_36h-ONECUT1_MA0679.3 9 bp overlap
Motif DE_48h DE_48h-ONECUT1_MA0679.3 9 bp overlap
PBX1 2 datasets
Motif DE_24h DE_24h-PBX1_MA0070.2 9 bp overlap
Motif DE_36h DE_36h-PBX1_MA0070.2 9 bp overlap
POU2F3 2 datasets
Motif DE_24h DE_24h-POU2F3_MA0627.3 9 bp overlap
Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap
POU3F1 3 datasets
Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap
Motif DE_36h DE_36h-POU3F1_MA0786.2 10 bp overlap
Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap
POU3F2 3 datasets
Motif DE_24h DE_24h-POU3F2_MA0787.1 12 bp overlap
Motif DE_36h DE_36h-POU3F2_MA0787.1 12 bp overlap
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
POU5F1 3 datasets
Motif DE_24h DE_24h-POU5F1_MA1115.2 7 bp overlap
Motif DE_48h DE_48h-POU5F1_MA1115.2 7 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 500 bp overlap
PRDM9 2 datasets
Motif DE_24h DE_24h-PRDM9_MA1723.2 20 bp overlap
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
RARA 3 datasets
Motif DE_24h DE_24h-RARA_MA0729.1 18 bp overlap
Motif DE_36h DE_36h-RARA_MA0729.1 18 bp overlap
Motif DE_48h DE_48h-RARA_MA0729.1 18 bp overlap
RREB1 2 datasets
Motif DE_24h DE_24h-RREB1_MA0073.2 19 bp overlap
Motif DE_36h DE_36h-RREB1_MA0073.2 19 bp overlap
RUNX3 2 datasets
Motif DE_24h DE_24h-RUNX3_MA0684.3 8 bp overlap
Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap
RXRA::VDR 3 datasets
Motif DE_24h DE_24h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_36h DE_36h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_48h DE_48h-RXRAVDR_MA0074.1 15 bp overlap
Rarb 3 datasets
Motif DE_24h DE_24h-Rarb_MA0857.1 16 bp overlap
Motif DE_36h DE_36h-Rarb_MA0857.1 16 bp overlap
Motif DE_48h DE_48h-Rarb_MA0857.1 16 bp overlap
Rfx6 2 datasets
Motif DE_24h DE_24h-Rfx6_MA1724.2 9 bp overlap
Motif DE_36h DE_36h-Rfx6_MA1724.2 9 bp overlap
SMAD2 5 datasets
Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap
Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 179 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 297 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 724 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 876 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 876 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 876 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 876 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 840 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 666 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 145 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 352 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 612 bp overlap
SP1 1 dataset
Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap
SP4 1 dataset
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
SP5 2 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
TRIM28 2 datasets
ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 167 bp overlap
ChIP hESC GSE115387.TRIM28.hESC 209 bp overlap
TRPS1 3 datasets
Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
ZIM3 2 datasets
Motif DE_24h DE_24h-ZIM3_MA1709.2 11 bp overlap
Motif DE_36h DE_36h-ZIM3_MA1709.2 11 bp overlap
ZKSCAN5 2 datasets
Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF140 4 datasets
Motif DE_12h DE_12h-ZNF140_MA1589.2 19 bp overlap
Motif DE_24h DE_24h-ZNF140_MA1589.2 19 bp overlap
Motif DE_36h DE_36h-ZNF140_MA1589.2 19 bp overlap
Motif DE_48h DE_48h-ZNF140_MA1589.2 19 bp overlap
ZNF148 2 datasets
Motif DE_36h DE_36h-ZNF148_MA1653.2 10 bp overlap
Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap
ZNF257 2 datasets
Motif DE_36h DE_36h-ZNF257_MA1710.2 10 bp overlap
Motif DE_48h DE_48h-ZNF257_MA1710.2 10 bp overlap
ZNF263 1 dataset
Motif DE_48h DE_48h-ZNF263_MA0528.3 7 bp overlap
ZNF281 3 datasets
Motif DE_36h DE_36h-ZNF281_MA1630.3 10 bp overlap
Motif DE_36h DE_36h-ZNF281_MA1630.3 10 bp overlap
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
ZNF317 2 datasets
Motif DE_24h DE_24h-ZNF317_MA1593.2 8 bp overlap
Motif DE_36h DE_36h-ZNF317_MA1593.2 8 bp overlap
ZNF354C 3 datasets
Motif DE_24h DE_24h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_36h DE_36h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap
ZNF44 3 datasets
ChIP HEK293T GSE78099.ZNF44.HEK293T 174 bp overlap
ChIP Hep-G2 ENCSR914HPP.ZNF44.Hep-G2 318 bp overlap
ChIP HepG2 ENCFF984YCN 464 bp overlap
ZNF582 3 datasets
Motif DE_24h DE_24h-ZNF582_MA1983.2 19 bp overlap
Motif DE_36h DE_36h-ZNF582_MA1983.2 19 bp overlap
Motif DE_48h DE_48h-ZNF582_MA1983.2 19 bp overlap
ZNF684 1 dataset
Motif DE_48h DE_48h-ZNF684_MA1600.2 14 bp overlap
Huangfu Lab · Publications · Resources · Contact