chr7:30,544,196–30,544,698

chr7 : 30,544,196 – 30,544,698

502 bp 40 TFs 7 linked genes

This 502 bp open chromatin element is linked to 7 target genes and is bound by 40 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000281039		6.1 kb	Proximal	Proximity
GGCT		39.7 kb	Distal	Multiome
GARS1-DT		50.2 kb	Distal	Multiome
GARS1		50.3 kb	Distal	Multiome
INMT		207.6 kb	Distal	Multiome
MINDY4		226.9 kb	Distal	Multiome
ZNRF2		259.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

40 transcription factors

Motif DE_48h DE_48h-BCL6_MA0463.3 13 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 263 bp overlap

ChIP SK-N-MC_SHFLI_96H GSE61944.ELF1.SK-N-MC_SHFLI_96H 261 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 217 bp overlap

FOXA1 1 dataset

ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 84 bp overlap

FOXA2 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 320 bp overlap

ChIP DE DE-FOXA2-1 370 bp overlap

ChIP DE DE-FOXA2-2 298 bp overlap

GABPA 3 datasets

ChIP Hep-G2 ENCSR269TNX.GABPA.Hep-G2 169 bp overlap

ChIP HepG2 ENCFF180FFY 331 bp overlap

ChIP K562 ENCFF139LXS 466 bp overlap

GATA1 4 datasets

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 151 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 222 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 158 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 192 bp overlap

GATA2 7 datasets

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

ChIP ESF GSE108408.GATA2.ESF 331 bp overlap

ChIP Hep-G2 ENCSR897LDT.GATA2.Hep-G2 143 bp overlap

ChIP HepG2 ENCFF905PYM 371 bp overlap

ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 171 bp overlap

GATA3 4 datasets

ChIP MCF-7 ENCFF352QVM 441 bp overlap

ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 191 bp overlap

ChIP MCF-7_E2_Dex GSE81510.GATA3.MCF-7_E2_Dex 150 bp overlap

ChIP T-47D_sc GSE122847.GATA3.T-47D_sc 179 bp overlap

GATA4 8 datasets

ChIP DE DE-GATA4-1 502 bp overlap

ChIP DE DE-GATA4-2 502 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 229 bp overlap

ChIP YCC-3 GSE51705.GATA4.YCC-3 336 bp overlap

ChIP foregut GSE117136.GATA4.foregut 292 bp overlap

GATA6 15 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 299 bp overlap

ChIP DE DE-GATA6-1 502 bp overlap

ChIP DE DE-GATA6-2 502 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 495 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 502 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 502 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 502 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 499 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 501 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 412 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 484 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 317 bp overlap

Gata3 3 datasets

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HOXB13 1 dataset

ChIP prostate-cancer_PDX_167 GSE130408.HOXB13.prostate-cancer_PDX_167 108 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 280 bp overlap

NFATC3 1 dataset

Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap

Nfatc1 1 dataset

Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 215 bp overlap

PAXIP1 1 dataset

ChIP HepG2 ENCFF526NOJ 387 bp overlap

POLR2A 1 dataset

ChIP spleen ENCFF044PYR 285 bp overlap

Prdm14 1 dataset

Motif DE_72h DE_72h-Prdm14_MA1998.2 8 bp overlap

Prdm4 1 dataset

Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 301 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 328 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 321 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 257 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 100 bp overlap

STAT1 1 dataset

Motif DE_48h DE_48h-STAT1_MA0137.4 9 bp overlap

STAT3 3 datasets

Motif DE_48h DE_48h-STAT3_MA0144.3 9 bp overlap

ChIP MCF-10A ENCSR000DOQ.STAT3.MCF-10A 130 bp overlap

ChIP MCF10A-Er-Src_TAM GSE115597.STAT3.MCF10A-Er-Src_TAM 196 bp overlap

Stat4 1 dataset

Motif DE_48h DE_48h-Stat4_MA0518.2 10 bp overlap

Stat5a 1 dataset

Motif DE_48h DE_48h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap

Stat5b 1 dataset

Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap

TEAD4 1 dataset

ChIP SK-MEL-147 GSE94488.TEAD4.SK-MEL-147 112 bp overlap

Motif DE_72h DE_72h-THRB_MA1576.2 18 bp overlap

ChIP foreskin GSE126390.TP63.foreskin 207 bp overlap

TRPS1 3 datasets

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ZNF184 1 dataset

Motif DE_48h DE_48h-ZNF184_MA2120.1 13 bp overlap

ZNF324 2 datasets

Motif DE_72h DE_72h-ZNF324_MA1977.2 14 bp overlap

Motif DE_72h DE_72h-ZNF324_MA1977.2 14 bp overlap

ZNF558 1 dataset

Motif DE_72h DE_72h-ZNF558_MA2335.1 29 bp overlap

ZNF677 1 dataset

Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap