Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

56 transcription factors

ASCL1 1 dataset

Motif DE_36h DE_36h-ASCL1_MA1631.2 9 bp overlap

CRX 4 datasets

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 197 bp overlap

ChIP retina_Hu21 GSE137311.CRX.retina_Hu21 220 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 241 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 333 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 558 bp overlap

EZH2 1 dataset

ChIP PC-9 ENCSR793USK.EZH2.PC-9 315 bp overlap

EZH2_phosphoT487 1 dataset

ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 405 bp overlap

FIGLA 1 dataset

Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 390 bp overlap

ChIP DE DE-FOXA2-1 179 bp overlap

ChIP DE DE-FOXA2-2 611 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 755 bp overlap

ChIP DE DE-GATA4-2 755 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 557 bp overlap

ChIP DE DE-GATA6-2 716 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 575 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 637 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 536 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 749 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 672 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 589 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 474 bp overlap

Hand1 1 dataset

Motif DE_36h DE_36h-Hand1_MA2123.1 9 bp overlap

JUN 3 datasets

ChIP DE_D2 S02-DE-d2-JUN-exp1 687 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 375 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 486 bp overlap

KLF16 2 datasets

Motif DE_36h DE_36h-KLF16_MA0741.1 11 bp overlap

Motif DE_48h DE_48h-KLF16_MA0741.1 11 bp overlap

MAFF 1 dataset

Motif DE_36h DE_36h-MAFF_MA0495.4 11 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 162 bp overlap

NR2C1 2 datasets

Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap

Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap

NR2C2 3 datasets

Motif DE_36h DE_36h-NR2C2_MA0504.2 14 bp overlap

Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap

Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap

NR2F1 3 datasets

Motif DE_36h DE_36h-NR2F1_MA0017.3 12 bp overlap

Motif DE_36h DE_36h-NR2F1_MA1537.2 13 bp overlap

Motif DE_60h DE_60h-NR2F1_MA0017.3 12 bp overlap

NR3C1 1 dataset

ChIP breast_tumor_Male_15 GSE104399.NR3C1.breast_tumor_Male_15 233 bp overlap

Nr1H2 2 datasets

Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap

Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 2 datasets

Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap

Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 2 datasets

Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap

Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap

Nr2f6 1 dataset

Motif DE_36h DE_36h-Nr2f6_MA0677.2 13 bp overlap

OTX2 1 dataset

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 383 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 421 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 327 bp overlap

PPARD 1 dataset

Motif DE_36h DE_36h-PPARD_MA1550.2 14 bp overlap

PTBP1 1 dataset

ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 170 bp overlap

Pparg::Rxra 1 dataset

Motif DE_36h DE_36h-PpargRxra_MA0065.3 13 bp overlap

RXRB 1 dataset

Motif DE_36h DE_36h-RXRB_MA0855.1 14 bp overlap

RXRG 1 dataset

Motif DE_36h DE_36h-RXRG_MA0856.1 14 bp overlap

Rxra 1 dataset

Motif DE_36h DE_36h-Rxra_MA0512.2 14 bp overlap

SMAD2 1 dataset

Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 554 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 670 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 563 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 667 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 560 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 698 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 554 bp overlap

SNAI1 1 dataset

Motif DE_36h DE_36h-SNAI1_MA1558.2 7 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 476 bp overlap

SP5 3 datasets

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

Six4 2 datasets

Motif DE_36h DE_36h-Six4_MA2001.2 7 bp overlap

Motif DE_48h DE_48h-Six4_MA2001.2 7 bp overlap

TCF12 1 dataset

Motif DE_36h DE_36h-TCF12_MA1648.2 7 bp overlap

TCF3 1 dataset

Motif DE_36h DE_36h-TCF3_MA0522.4 7 bp overlap

THRB 1 dataset

Motif DE_36h DE_36h-THRB_MA1574.2 13 bp overlap

Wt1 1 dataset

Motif DE_48h DE_48h-Wt1_MA1627.2 10 bp overlap

ZEB1 1 dataset

Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap

ZFP14 2 datasets

Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap

Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap

ZNF135 2 datasets

Motif DE_36h DE_36h-ZNF135_MA1587.1 14 bp overlap

Motif DE_60h DE_60h-ZNF135_MA1587.1 14 bp overlap

ZNF610 2 datasets

Motif DE_36h DE_36h-ZNF610_MA1713.2 10 bp overlap

Motif DE_48h DE_48h-ZNF610_MA1713.2 10 bp overlap

ZNF682 2 datasets

Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap

Motif DE_48h DE_48h-ZNF682_MA1599.2 11 bp overlap

ZNF692 1 dataset

Motif DE_36h DE_36h-ZNF692_MA1986.2 8 bp overlap

ZNF708 1 dataset

Motif DE_36h DE_36h-ZNF708_MA1730.2 9 bp overlap

ZNF75D 1 dataset

Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap

ZNF768 1 dataset

Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap

ZSCAN5C 2 datasets

ChIP HEK293 ENCFF343DTU 235 bp overlap

ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 121 bp overlap

Zic1::Zic2 1 dataset

Motif DE_36h DE_36h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 1 dataset

Motif DE_36h DE_36h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_36h DE_36h-Zic3_MA0697.3 7 bp overlap

Znf423 1 dataset

Motif DE_36h DE_36h-Znf423_MA0116.1 15 bp overlap

Gene	Dist. to TSS	Distance	Link type
DACT2	196.1 kb	Distal	Multiome
AFDN	296.8 kb	Distal	Multiome
AFDN-DT	296.9 kb	Distal	Multiome

Genome Browser