chr5 : 36,590,574 – 36,590,890

316 bp 62 TFs 1 linked gene

This 316 bp open chromatin element is linked to SLC1A3 and is bound by 62 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
SLC1A3		5.7 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

62 transcription factors

ARNTL 1 dataset

ChIP U2OS_DMOG GSE85096.ARNTL.U2OS_DMOG 231 bp overlap

BCL11A 1 dataset

ChIP WA01 ENCSR000BIP.BCL11A.WA01 125 bp overlap

BRD4 1 dataset

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 297 bp overlap

CHD7 2 datasets

ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 275 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 316 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 207 bp overlap

CTCF 1 dataset

ChIP heart_left-ventricle ENCSR791AYW.CTCF.heart_left-ventricle 127 bp overlap

Dmrt1 1 dataset

Motif ES_0h ES_0h-Dmrt1_MA1603.2 9 bp overlap

E2F6 1 dataset

Motif ES_0h ES_0h-E2F6_MA0471.3 8 bp overlap

FLI1 2 datasets

ChIP A-673_D14 GSE129155.FLI1.A-673_D14 251 bp overlap

ChIP A-673_D17 GSE129155.FLI1.A-673_D17 316 bp overlap

FOSL2 2 datasets

ChIP NPC_K755R-pos GSE122631.FOSL2.NPC_K755R-pos 199 bp overlap

ChIP NPC_R1159Q GSE122631.FOSL2.NPC_R1159Q 149 bp overlap

GATA6 7 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 316 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 316 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 316 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 250 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 316 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 316 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 271 bp overlap

GCM1 1 dataset

Motif ES_0h ES_0h-GCM1_MA0646.2 10 bp overlap

Gli1 1 dataset

Motif DE_12h DE_12h-Gli1_MA1990.2 10 bp overlap

HDAC2 2 datasets

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 179 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 178 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 218 bp overlap

IKZF3 1 dataset

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 167 bp overlap

IRF2BP2 1 dataset

ChIP HEK293 GSE124636.IRF2BP2.HEK293 315 bp overlap

IRF7 1 dataset

Motif ES_0h ES_0h-IRF7_MA0772.2 13 bp overlap

Irf1 1 dataset

Motif ES_0h ES_0h-Irf1_MA0050.4 11 bp overlap

JUN 1 dataset

ChIP HUES-8 GSE109524.JUN.HUES-8 290 bp overlap

MAFF 1 dataset

Motif ES_0h ES_0h-MAFF_MA0495.4 11 bp overlap

MTA2 1 dataset

ChIP RH4 GSE155861.MTA2.RH4 209 bp overlap

MYOD1 1 dataset

ChIP myoblast GSE50413.MYOD1.myoblast 120 bp overlap

Mafb 1 dataset

Motif ES_0h ES_0h-Mafb_MA0117.3 11 bp overlap

NANOG 6 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 316 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 283 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 247 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 316 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 316 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 316 bp overlap

NIPBL 1 dataset

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 183 bp overlap

NR3C1 3 datasets

ChIP SUP-B15_DEX GSE107584.NR3C1.SUP-B15_DEX 244 bp overlap

ChIP U2OS_GLUCC ERP007081.NR3C1.U2OS_GLUCC 89 bp overlap

ChIP U2OS_SHHIC5 GSE65847.NR3C1.U2OS_SHHIC5 180 bp overlap

NRL 1 dataset

Motif ES_0h ES_0h-NRL_MA0842.3 12 bp overlap

POU5F1 2 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 316 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 316 bp overlap

Pparg::Rxra 1 dataset

Motif ES_0h ES_0h-PpargRxra_MA0065.3 13 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 314 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 240 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 222 bp overlap

SMARCA2 4 datasets

ChIP NPC_K755R-pos GSE122631.SMARCA2.NPC_K755R-pos 316 bp overlap

ChIP NPC_K755R-siAP GSE122631.SMARCA2.NPC_K755R-siAP 262 bp overlap

ChIP NPC_K755R-siCT GSE122631.SMARCA2.NPC_K755R-siCT 316 bp overlap

ChIP NPC_R1159Q GSE122631.SMARCA2.NPC_R1159Q 225 bp overlap

SMARCA4 4 datasets

ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 316 bp overlap

ChIP NPC_K755R-siCT GSE122631.SMARCA4.NPC_K755R-siCT 316 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 316 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 316 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 283 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 263 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 246 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 316 bp overlap

SNAI2 1 dataset

ChIP RD GSE137168.SNAI2.RD 228 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 246 bp overlap

SOX2 2 datasets

ChIP HNSC GSE69479.SOX2.HNSC 316 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 249 bp overlap

SOX8 1 dataset

ChIP RH4 GSE116344.SOX8.RH4 250 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 202 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 304 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 131 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 228 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 267 bp overlap

Wt1 1 dataset

Motif ES_0h ES_0h-Wt1_MA1627.2 10 bp overlap

ZBTB12 1 dataset

ChIP HEK293 ENCSR543KOA.ZBTB12.HEK293 233 bp overlap

ZBTB24 1 dataset

Motif ES_0h ES_0h-ZBTB24_MA2330.1 10 bp overlap

ZBTB8A 2 datasets

ChIP HEK293 ENCFF303WRD 316 bp overlap

ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 314 bp overlap

ZFP69B 1 dataset

ChIP HEK293T GSE78099.ZFP69B.HEK293T 170 bp overlap

ZIC1 1 dataset

Motif ES_0h ES_0h-ZIC1_MA0696.1 14 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 316 bp overlap

ZKSCAN1 1 dataset

Motif ES_0h ES_0h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF205 1 dataset

ChIP HEK293T GSE78099.ZNF205.HEK293T 101 bp overlap

ZNF213 1 dataset

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCFF784SLD 316 bp overlap

ZNF341 1 dataset

ChIP HEK293 GSE76494.ZNF341.HEK293 77 bp overlap

ZNF75A 1 dataset

Motif ES_0h ES_0h-ZNF75A_MA2097.1 12 bp overlap

ZNF75D 1 dataset

Motif ES_0h ES_0h-ZNF75D_MA1601.2 12 bp overlap

Zic1::Zic2 1 dataset

Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 2 datasets

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Motif ES_0h ES_0h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap