chr4 : 143,505,920 – 143,506,427
507 bp 76 TFs 2 linked genes
This 507 bp open chromatin element is linked to SMARCA5 and SMARCA5-AS1 and is bound by 76 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SMARCA5 7.3 kb Proximal Proximity
SMARCA5-AS1 8.2 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:143,500,920 – 143,511,427
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
76 transcription factors
Source
Cell type
ASCL1 1 dataset
Motif DE_36h DE_36h-ASCL1_MA1631.2 9 bp overlap
Crx 6 datasets
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Dmbx1 3 datasets
Motif DE_36h DE_36h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap
EMSY 1 dataset
ChIP K562 ENCFF511ZZZ 246 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 222 bp overlap
ERF::FOXI1 1 dataset
Motif DE_36h DE_36h-ERFFOXI1_MA1935.2 10 bp overlap
ETV2::FOXI1 1 dataset
Motif DE_36h DE_36h-ETV2FOXI1_MA1942.2 11 bp overlap
ETV5::FIGLA 1 dataset
Motif DE_36h DE_36h-ETV5FIGLA_MA1945.2 14 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 1 dataset
ChIP DND41 ENCSR000ASW.EZH2.DND41 87 bp overlap
Erg 1 dataset
Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap
FIGLA 1 dataset
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
FLI1::FOXI1 1 dataset
Motif DE_36h DE_36h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 311 bp overlap
ChIP DE DE-FOXA2-2 296 bp overlap
FOXE1 1 dataset
Motif DE_36h DE_36h-FOXE1_MA1487.3 12 bp overlap
FOXJ2::ELF1 1 dataset
Motif DE_36h DE_36h-FOXJ2ELF1_MA1952.2 11 bp overlap
GABPA 1 dataset
Motif DE_36h DE_36h-GABPA_MA0062.4 10 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 429 bp overlap
ChIP DE DE-GATA4-2 480 bp overlap
GATA6 7 datasets
ChIP DE DE-GATA6-1 465 bp overlap
ChIP DE DE-GATA6-2 473 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 359 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 340 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 449 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 276 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 328 bp overlap
GSC 6 datasets
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
GSC2 6 datasets
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
HOXB13 1 dataset
Motif DE_36h DE_36h-HOXB13_MA0901.3 9 bp overlap
HOXC13 1 dataset
Motif DE_36h DE_36h-HOXC13_MA0907.2 9 bp overlap
IKZF1 1 dataset
Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap
IRF3 1 dataset
Motif DE_36h DE_36h-IRF3_MA1418.2 17 bp overlap
KLF1 2 datasets
Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap
Motif DE_48h DE_48h-KLF1_MA0493.3 8 bp overlap
KLF10 2 datasets
Motif DE_36h DE_36h-KLF10_MA1511.2 9 bp overlap
Motif DE_48h DE_48h-KLF10_MA1511.2 9 bp overlap
KLF14 2 datasets
Motif DE_36h DE_36h-KLF14_MA0740.2 9 bp overlap
Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap
KLF2 2 datasets
Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap
Motif DE_48h DE_48h-KLF2_MA1515.2 8 bp overlap
KLF4 2 datasets
Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap
Motif DE_48h DE_48h-KLF4_MA0039.5 8 bp overlap
KLF5 2 datasets
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
MAFF 1 dataset
ChIP HepG2 ENCFF452YUT 129 bp overlap
MEIS1 1 dataset
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
MXI1 3 datasets
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap
MYBL2 1 dataset
Motif DE_36h DE_36h-MYBL2_MA0777.1 15 bp overlap
MZF1 5 datasets
Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap
Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
ONECUT2 1 dataset
ChIP A-549 GSE102599.ONECUT2.A-549 109 bp overlap
OTX1 6 datasets
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
OTX2 6 datasets
Motif DE_36h DE_36h-OTX2_MA0712.3 7 bp overlap
Motif DE_36h DE_36h-OTX2_MA0712.3 7 bp overlap
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
Motif DE_60h DE_60h-OTX2_MA0712.3 7 bp overlap
Motif DE_60h DE_60h-OTX2_MA0712.3 7 bp overlap
PITX1 6 datasets
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
PITX2 3 datasets
Motif DE_36h DE_36h-PITX2_MA1547.2 8 bp overlap
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
PITX3 6 datasets
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
RHOXF1 6 datasets
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
RNF2 1 dataset
ChIP fibroblast GSE139053.RNF2.fibroblast 66 bp overlap
SCRT1 1 dataset
Motif DE_36h DE_36h-SCRT1_MA0743.3 10 bp overlap
SCRT2 1 dataset
Motif DE_36h DE_36h-SCRT2_MA0744.3 10 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 347 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 334 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 218 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 351 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 507 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 507 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 186 bp overlap
SNAI1 1 dataset
Motif DE_36h DE_36h-SNAI1_MA1558.2 7 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 315 bp overlap
SP5 2 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
STAT1_pS727 1 dataset
ChIP SET-2 GSE100566.STAT1_pS727.SET-2 225 bp overlap
Smad4 3 datasets
Motif DE_36h DE_36h-Smad4_MA1153.2 7 bp overlap
Motif DE_48h DE_48h-Smad4_MA1153.2 7 bp overlap
Motif DE_60h DE_60h-Smad4_MA1153.2 7 bp overlap
Spi1 1 dataset
Motif DE_36h DE_36h-Spi1_MA0080.7 13 bp overlap
Spz1 2 datasets
Motif DE_36h DE_36h-Spz1_MA0111.1 11 bp overlap
Motif DE_48h DE_48h-Spz1_MA0111.1 11 bp overlap
TBP 1 dataset
Motif DE_36h DE_36h-TBP_MA0108.3 7 bp overlap
TBX18 1 dataset
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
TCF12 1 dataset
Motif DE_36h DE_36h-TCF12_MA1648.2 7 bp overlap
TCF3 1 dataset
Motif DE_36h DE_36h-TCF3_MA0522.4 7 bp overlap
ZEB1 1 dataset
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
ZIC1 3 datasets
Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap
Motif DE_48h DE_48h-ZIC1_MA0696.1 14 bp overlap
Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap
ZKSCAN5 2 datasets
Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
ZMYM3 1 dataset
ChIP K-562 ENCSR102KIN.ZMYM3.K-562 142 bp overlap
ZNF189 4 datasets
Motif DE_36h DE_36h-ZNF189_MA1725.2 9 bp overlap
Motif DE_36h DE_36h-ZNF189_MA1725.2 9 bp overlap
Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
ZNF274 3 datasets
Motif DE_36h DE_36h-ZNF274_MA1592.2 12 bp overlap
Motif DE_48h DE_48h-ZNF274_MA1592.2 12 bp overlap
Motif DE_60h DE_60h-ZNF274_MA1592.2 12 bp overlap
ZNF316 1 dataset
ChIP K562 ENCFF838QCD 130 bp overlap
ZNF341 3 datasets
Motif DE_36h DE_36h-ZNF341_MA1655.2 8 bp overlap
Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap
Motif DE_60h DE_60h-ZNF341_MA1655.2 8 bp overlap
ZNF449 1 dataset
Motif DE_36h DE_36h-ZNF449_MA1656.2 10 bp overlap
ZNF582 1 dataset
Motif DE_36h DE_36h-ZNF582_MA1983.2 19 bp overlap
ZNF677 3 datasets
Motif DE_36h DE_36h-ZNF677_MA2101.1 12 bp overlap
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
ZNF701 7 datasets
Motif DE_36h DE_36h-ZNF701_MA1987.2 17 bp overlap
Motif DE_36h DE_36h-ZNF701_MA1987.2 17 bp overlap
Motif DE_36h DE_36h-ZNF701_MA1987.2 17 bp overlap
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
ZNF740 2 datasets
Motif DE_36h DE_36h-ZNF740_MA0753.3 10 bp overlap
Motif DE_48h DE_48h-ZNF740_MA0753.3 10 bp overlap
ZNF768 1 dataset
Motif DE_36h DE_36h-ZNF768_MA1731.2 9 bp overlap
Zic1::Zic2 1 dataset
Motif DE_36h DE_36h-Zic1Zic2_MA1628.2 7 bp overlap
Zic3 1 dataset
Motif DE_36h DE_36h-Zic3_MA0697.3 7 bp overlap
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