chr4 : 133,261,419 – 133,261,975

556 bp 66 TFs 1 linked gene

This 556 bp open chromatin element is linked to ENSG00000286467 and is bound by 66 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000286467		1.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

66 transcription factors

Arid3a 1 dataset

Motif ES_0h ES_0h-Arid3a_MA0151.1 6 bp overlap

CEBPA 1 dataset

Motif DE_12h DE_12h-CEBPA_MA0102.5 10 bp overlap

CEBPB 2 datasets

ChIP H1 ENCFF871PTR 180 bp overlap

ChIP WA01 ENCSR000EBV.CEBPB.WA01 103 bp overlap

CEBPD 1 dataset

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

CHD1 1 dataset

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 81 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF460KDD 224 bp overlap

ESRRA 2 datasets

Motif DE_12h DE_12h-ESRRA_MA0592.4 9 bp overlap

Motif DE_24h DE_24h-ESRRA_MA0592.4 9 bp overlap

ESRRB 2 datasets

Motif DE_12h DE_12h-ESRRB_MA0141.4 10 bp overlap

Motif DE_24h DE_24h-ESRRB_MA0141.4 10 bp overlap

Esrrg 2 datasets

Motif DE_12h DE_12h-Esrrg_MA0643.2 9 bp overlap

Motif DE_24h DE_24h-Esrrg_MA0643.2 9 bp overlap

FEZF2 1 dataset

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

FOXC2 1 dataset

Motif ES_0h ES_0h-FOXC2_MA0846.2 11 bp overlap

FOXE1 1 dataset

Motif ES_0h ES_0h-FOXE1_MA1487.3 12 bp overlap

GATA6 2 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 308 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 298 bp overlap

Hnf1A 1 dataset

Motif ES_0h ES_0h-Hnf1A_MA1991.2 10 bp overlap

JUN 1 dataset

ChIP DE_D1 S40-DE-d1-JUN-exp2 359 bp overlap

Lef1 1 dataset

Motif ES_0h ES_0h-Lef1_MA0768.3 8 bp overlap

Lhx1 1 dataset

Motif ES_0h ES_0h-Lhx1_MA1518.3 10 bp overlap

MAFG::NFE2L1 1 dataset

Motif DE_12h DE_12h-MAFGNFE2L1_MA0089.3 11 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MYB 2 datasets

Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap

Motif ES_0h ES_0h-MYB_MA0100.4 6 bp overlap

Mafb 2 datasets

Motif DE_12h DE_12h-Mafb_MA0117.3 11 bp overlap

Motif ES_0h ES_0h-Mafb_MA0117.3 11 bp overlap

NANOG 7 datasets

ChIP GM23338 ENCFF065NZG 277 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 352 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 148 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 556 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 383 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 262 bp overlap

ChIP hESC GSE18292.NANOG.hESC 151 bp overlap

NR1I2 3 datasets

Motif DE_12h DE_12h-NR1I2_MA1533.2 15 bp overlap

Motif DE_24h DE_24h-NR1I2_MA1533.2 15 bp overlap

Motif ES_0h ES_0h-NR1I2_MA1533.2 15 bp overlap

NR2C1 2 datasets

Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap

Motif DE_24h DE_24h-NR2C1_MA1535.2 6 bp overlap

NR2C2 2 datasets

Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap

Motif DE_24h DE_24h-NR2C2_MA1536.2 6 bp overlap

NR2F2 2 datasets

Motif DE_12h DE_12h-NR2F2_MA1111.2 7 bp overlap

Motif DE_24h DE_24h-NR2F2_MA1111.2 7 bp overlap

NR5A1 3 datasets

Motif DE_12h DE_12h-NR5A1_MA1540.3 12 bp overlap

Motif DE_24h DE_24h-NR5A1_MA1540.3 12 bp overlap

Motif ES_0h ES_0h-NR5A1_MA1540.3 12 bp overlap

NRL 2 datasets

Motif DE_12h DE_12h-NRL_MA0842.3 12 bp overlap

Motif ES_0h ES_0h-NRL_MA0842.3 12 bp overlap

Nfatc2 1 dataset

Motif ES_0h ES_0h-Nfatc2_MA0152.3 8 bp overlap

Nr1H2 2 datasets

Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap

Motif DE_24h DE_24h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 2 datasets

Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap

Motif DE_24h DE_24h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 2 datasets

Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap

Motif DE_24h DE_24h-Nr1h3_MA2337.1 6 bp overlap

Nr5A2 2 datasets

Motif DE_12h DE_12h-Nr5A2_MA0505.3 9 bp overlap

Motif DE_24h DE_24h-Nr5A2_MA0505.3 9 bp overlap

PAX5 2 datasets

Motif DE_12h DE_12h-PAX5_MA0014.4 8 bp overlap

Motif DE_24h DE_24h-PAX5_MA0014.4 8 bp overlap

POU1F1 1 dataset

Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap

POU2F1::SOX2 1 dataset

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU3F2 1 dataset

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU4F2 1 dataset

Motif ES_0h ES_0h-POU4F2_MA0683.2 15 bp overlap

POU5F1 5 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 407 bp overlap

ChIP GM23338 ENCFF333SNB 254 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 253 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 213 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 184 bp overlap

Pou5f1::Sox2 1 dataset

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

Ppara 2 datasets

Motif DE_12h DE_12h-Ppara_MA2338.1 7 bp overlap

Motif DE_24h DE_24h-Ppara_MA2338.1 7 bp overlap

RARB 2 datasets

Motif DE_12h DE_12h-RARB_MA1552.2 13 bp overlap

Motif DE_24h DE_24h-RARB_MA1552.2 13 bp overlap

RARG 2 datasets

Motif DE_12h DE_12h-RARG_MA1553.2 13 bp overlap

Motif DE_24h DE_24h-RARG_MA1553.2 13 bp overlap

RORA 2 datasets

Motif DE_12h DE_12h-RORA_MA0071.1 10 bp overlap

Motif DE_24h DE_24h-RORA_MA0071.1 10 bp overlap

RORB 1 dataset

Motif DE_12h DE_12h-RORB_MA1150.2 10 bp overlap

RUNX3 3 datasets

Motif DE_12h DE_12h-RUNX3_MA0684.3 8 bp overlap

Motif DE_24h DE_24h-RUNX3_MA0684.3 8 bp overlap

Motif ES_0h ES_0h-RUNX3_MA0684.3 8 bp overlap

RXRB 2 datasets

Motif DE_12h DE_12h-RXRB_MA1555.1 14 bp overlap

Motif DE_24h DE_24h-RXRB_MA1555.1 14 bp overlap

RXRG 2 datasets

Motif DE_12h DE_12h-RXRG_MA1556.1 14 bp overlap

Motif DE_24h DE_24h-RXRG_MA1556.1 14 bp overlap

SMAD2-3 1 dataset

ChIP HGrC1_EV-TGF GSE138496.SMAD2-3.HGrC1_EV-TGF 126 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 324 bp overlap

SMARCA4 1 dataset

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 188 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 130 bp overlap

SOX14 1 dataset

Motif DE_24h DE_24h-SOX14_MA1562.2 9 bp overlap

SRY 1 dataset

Motif DE_24h DE_24h-SRY_MA0084.2 7 bp overlap

Stat4 1 dataset

Motif ES_0h ES_0h-Stat4_MA0518.2 10 bp overlap

Stat6 1 dataset

Motif DE_12h DE_12h-Stat6_MA0520.2 10 bp overlap

TGIF2 2 datasets

Motif DE_12h DE_12h-TGIF2_MA0797.1 12 bp overlap

Motif ES_0h ES_0h-TGIF2_MA0797.1 12 bp overlap

THRB 2 datasets

Motif DE_12h DE_12h-THRB_MA1576.2 18 bp overlap

Motif DE_24h DE_24h-THRB_MA1576.2 18 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 222 bp overlap

ZKSCAN5 3 datasets

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

Motif DE_24h DE_24h-ZKSCAN5_MA1652.2 9 bp overlap

Motif ES_0h ES_0h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 297 bp overlap

ZNF213 1 dataset

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

ZNF257 3 datasets

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

Motif DE_24h DE_24h-ZNF257_MA1710.2 10 bp overlap

Motif ES_0h ES_0h-ZNF257_MA1710.2 10 bp overlap

ZNF331 1 dataset

Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap