chr4 : 58,564,611 – 58,565,332

721 bp 58 TFs 1 linked gene

This 721 bp open chromatin element is linked to ENSG00000250078 and is bound by 58 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000250078		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

58 transcription factors

BCL11A 1 dataset

ChIP GM12878 ENCSR000BHA.BCL11A.GM12878 109 bp overlap

BHLHE22 1 dataset

Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap

CDX2 1 dataset

ChIP intestinal-cell GSE115314.CDX2.intestinal-cell 168 bp overlap

CREB1 4 datasets

ChIP Hep-G2 ENCSR112ALD.CREB1.Hep-G2 196 bp overlap

ChIP MCF-7 ENCFF341ZEM 379 bp overlap

ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 344 bp overlap

ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 238 bp overlap

CREBBP 2 datasets

ChIP LS180_125 GSE39277.CREBBP.LS180_125 81 bp overlap

ChIP MCF-7 ERP000901.CREBBP.MCF-7 257 bp overlap

CRY1 1 dataset

ChIP U2OS_cordycepin GSE130506.CRY1.U2OS_cordycepin 255 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF896HSY 268 bp overlap

DPF2 1 dataset

ChIP GM12878 ENCSR509FWH.DPF2.GM12878 347 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 294 bp overlap

EP300 2 datasets

ChIP neural ENCSR843ZUP.EP300.neural 612 bp overlap

ChIP neural cell ENCFF442QNK 573 bp overlap

ERF::FOXI1 1 dataset

Motif DE_60h DE_60h-ERFFOXI1_MA1935.2 10 bp overlap

ERF::FOXO1 1 dataset

Motif DE_60h DE_60h-ERFFOXO1_MA1936.2 12 bp overlap

Elf5 1 dataset

Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap

FOS 1 dataset

ChIP MCF-7 ENCSR569XNP.FOS.MCF-7 205 bp overlap

FOXA1 4 datasets

ChIP 22Rv1_i176m_CST GSE123618.FOXA1.22Rv1_i176m_CST 157 bp overlap

ChIP CFPAC-1_FOXA1-KO GSE119930.FOXA1.CFPAC-1_FOXA1-KO 256 bp overlap

ChIP LNCaP_FENG_shFOXA1_Ethanol GSE128883.FOXA1.LNCaP_FENG_shFOXA1_Ethanol 346 bp overlap

ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 470 bp overlap

FOXA2 4 datasets

ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 245 bp overlap

ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 420 bp overlap

ChIP DE DE-FOXA2-1 617 bp overlap

ChIP DE DE-FOXA2-2 545 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_60h DE_60h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_60h DE_60h-FOXO1ELK1_MA1954.2 13 bp overlap

GATA3 1 dataset

ChIP Kelly GSE65664.GATA3.Kelly 161 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 645 bp overlap

ChIP DE DE-GATA4-2 659 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 483 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 639 bp overlap

ChIP DE DE-GATA6-2 624 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 478 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 328 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 508 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 476 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 345 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 522 bp overlap

HAND2 1 dataset

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 206 bp overlap

HDAC2 1 dataset

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 204 bp overlap

HNF4A 1 dataset

ChIP gastric-epithelial-cell_OE GSE114018.HNF4A.gastric-epithelial-cell_OE 167 bp overlap

HOXB8 1 dataset

ChIP CFPAC-1_HOXB8-OE GSE119930.HOXB8.CFPAC-1_HOXB8-OE 274 bp overlap

IKZF1 1 dataset

Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap

JUND 1 dataset

ChIP Kasumi-1_ctrl GSE117105.JUND.Kasumi-1_ctrl 121 bp overlap

MEIS1 2 datasets

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

MLLT1 1 dataset

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 140 bp overlap

MTA2 1 dataset

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 234 bp overlap

NCOR1 1 dataset

ChIP LS180_125 GSE39277.NCOR1.LS180_125 101 bp overlap

NR3C1 1 dataset

ChIP U2OS_SHHIC5 GSE65847.NR3C1.U2OS_SHHIC5 209 bp overlap

NUP98-HOXA9 1 dataset

ChIP HEK293-FT GSE62586.NUP98-HOXA9.HEK293-FT 271 bp overlap

Neurod2 1 dataset

Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap

PKNOX1 1 dataset

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 310 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 338 bp overlap

Prdm5 1 dataset

Motif DE_60h DE_60h-Prdm5_MA1999.2 11 bp overlap

RAD21 1 dataset

ChIP neural cell ENCFF564MOT 505 bp overlap

REST 2 datasets

ChIP neural ENCSR000BTV.REST.neural 248 bp overlap

ChIP neural cell ENCFF882LXX 505 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 133 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 423 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 384 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 287 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 194 bp overlap

SMC3 1 dataset

ChIP neural cell ENCFF795YGY 531 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 312 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 375 bp overlap

SOX8 1 dataset

ChIP RH4 GSE116344.SOX8.RH4 297 bp overlap

SPIC 1 dataset

Motif DE_60h DE_60h-SPIC_MA0687.2 13 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 195 bp overlap

TCF12 1 dataset

ChIP GM12878 ENCSR000BGZ.TCF12.GM12878 95 bp overlap

Tcf12 1 dataset

Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap

VDR 1 dataset

ChIP kidney-cortex GSE129585.VDR.kidney-cortex 210 bp overlap

ZNF140 1 dataset

Motif DE_60h DE_60h-ZNF140_MA1589.2 19 bp overlap

ZNF667 1 dataset

Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap

ZNF677 1 dataset

Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap