chr4 : 16,897,403 – 16,897,713

310 bp 43 TFs 1 linked gene

This 310 bp open chromatin element is linked to LDB2 and is bound by 43 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
LDB2		964 bp	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

43 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 310 bp overlap

ATRX 1 dataset

ChIP metastatic-neuroblastoma_CHLA90 GSE100148.ATRX.metastatic-neuroblastoma_CHLA90 310 bp overlap

BRD1 1 dataset

ChIP HUES-64 GSE104059.BRD1.HUES-64 223 bp overlap

BRD4 5 datasets

ChIP CHL-1_OTX015 GSE95585.BRD4.CHL-1_OTX015 310 bp overlap

ChIP HUVEC-C GSE53998.BRD4.HUVEC-C 261 bp overlap

ChIP MDA-MB-231_JQ1 GSE116879.BRD4.MDA-MB-231_JQ1 215 bp overlap

ChIP MDA-MB-231_JQ1_rDNA GSE116879.BRD4.MDA-MB-231_JQ1_rDNA 215 bp overlap

ChIP hESC GSE33281.BRD4.hESC 67 bp overlap

Bach1::Mafk 1 dataset

Motif DE_12h DE_12h-Bach1Mafk_MA0591.2 12 bp overlap

CHD1 1 dataset

ChIP WA01 ENCSR000AQK.CHD1.WA01 105 bp overlap

ETS1 1 dataset

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 213 bp overlap

EZH2 3 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 50 bp overlap

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 158 bp overlap

ChIP HCT-116 ENCSR046HGP.EZH2.HCT-116 267 bp overlap

FEZF2 1 dataset

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

HMGB1 1 dataset

ChIP IMR-90 GSE98245.HMGB1.IMR-90 275 bp overlap

HMGB2 1 dataset

ChIP HUVEC-C GSE98245.HMGB2.HUVEC-C 310 bp overlap

MAFK 1 dataset

Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap

MED1 1 dataset

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 265 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 310 bp overlap

Mafg 1 dataset

Motif DE_12h DE_12h-Mafg_MA0659.4 12 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 310 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 310 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 288 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 2 datasets

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 160 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU4F1 1 dataset

Motif DE_12h DE_12h-POU4F1_MA0790.2 12 bp overlap

POU4F2 1 dataset

Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap

POU4F3 1 dataset

Motif DE_12h DE_12h-POU4F3_MA0791.2 12 bp overlap

POU5F1 6 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 253 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 310 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 310 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 165 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 310 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

RAD21 2 datasets

ChIP HUVEC-C_hypoxia GSE94872.RAD21.HUVEC-C_hypoxia 310 bp overlap

ChIP IMR-90 ENCSR000EFJ.RAD21.IMR-90 160 bp overlap

RELA 3 datasets

ChIP aortic-endothelial-cell_IL1B_D10 GSE139377.RELA.aortic-endothelial-cell_IL1B_D10 125 bp overlap

ChIP aortic-endothelial-cell_IL1B_D8 GSE139377.RELA.aortic-endothelial-cell_IL1B_D8 140 bp overlap

ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 223 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 50 bp overlap

SIN3A 5 datasets

ChIP H1 ENCFF042ZSL 279 bp overlap

ChIP SK-N-SH ENCSR000BPB.SIN3A.SK-N-SH 136 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 103 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 133 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 107 bp overlap

SIX2 1 dataset

Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap

SMARCA4 4 datasets

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 289 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 152 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 310 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 281 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 310 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 310 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 310 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 310 bp overlap

SMC1 1 dataset

ChIP HCAEC GSE101921.SMC1.HCAEC 299 bp overlap

TCF7L2 1 dataset

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

YY1 1 dataset

ChIP liver ENCFF400MBC 193 bp overlap

ZNF135 1 dataset

Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap

ZNF460 1 dataset

Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap

ZNF770 1 dataset

Motif DE_12h DE_12h-ZNF770_MA2099.1 8 bp overlap

Zfp335 1 dataset

Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap