chr4 : 10,944,088 – 10,944,677
589 bp 71 TFs 2 linked genes
This 589 bp open chromatin element is linked to HS3ST1 and ENSG00000287778 and is bound by 71 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
HS3ST1 484.4 kb Distal Multiome+HiCAR
ENSG00000287778 485.1 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:10,939,088 – 10,949,677
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
71 transcription factors
Source
Cell type
CDX1 1 dataset
Motif DE_60h DE_60h-CDX1_MA0878.3 10 bp overlap
CDX2 1 dataset
Motif DE_60h DE_60h-CDX2_MA0465.3 8 bp overlap
CTCF 5 datasets
Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap
Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap
Motif DE_60h DE_60h-CTCF_MA1929.2 31 bp overlap
Motif DE_72h DE_72h-CTCF_MA1929.2 31 bp overlap
ChIP keratinocyte ENCSR000DNC.CTCF.keratinocyte 100 bp overlap
EHF 4 datasets
Motif DE_36h DE_36h-EHF_MA0598.4 9 bp overlap
Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap
Motif DE_60h DE_60h-EHF_MA0598.4 9 bp overlap
Motif DE_72h DE_72h-EHF_MA0598.4 9 bp overlap
ELF1 4 datasets
Motif DE_36h DE_36h-ELF1_MA0473.4 9 bp overlap
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
Motif DE_60h DE_60h-ELF1_MA0473.4 9 bp overlap
Motif DE_72h DE_72h-ELF1_MA0473.4 9 bp overlap
ELF2 4 datasets
Motif DE_36h DE_36h-ELF2_MA1483.3 10 bp overlap
Motif DE_48h DE_48h-ELF2_MA1483.3 10 bp overlap
Motif DE_60h DE_60h-ELF2_MA1483.3 10 bp overlap
Motif DE_72h DE_72h-ELF2_MA1483.3 10 bp overlap
ELF3 4 datasets
Motif DE_36h DE_36h-ELF3_MA0640.3 9 bp overlap
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
Motif DE_60h DE_60h-ELF3_MA0640.3 9 bp overlap
Motif DE_72h DE_72h-ELF3_MA0640.3 9 bp overlap
ELF4 4 datasets
Motif DE_36h DE_36h-ELF4_MA0641.1 12 bp overlap
Motif DE_48h DE_48h-ELF4_MA0641.1 12 bp overlap
Motif DE_60h DE_60h-ELF4_MA0641.1 12 bp overlap
Motif DE_72h DE_72h-ELF4_MA0641.1 12 bp overlap
ELK4 4 datasets
Motif DE_36h DE_36h-ELK4_MA0076.3 9 bp overlap
Motif DE_48h DE_48h-ELK4_MA0076.3 9 bp overlap
Motif DE_60h DE_60h-ELK4_MA0076.3 9 bp overlap
Motif DE_72h DE_72h-ELK4_MA0076.3 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 316 bp overlap
ERF::HOXB13 4 datasets
Motif DE_36h DE_36h-ERFHOXB13_MA1937.2 13 bp overlap
Motif DE_48h DE_48h-ERFHOXB13_MA1937.2 13 bp overlap
Motif DE_60h DE_60h-ERFHOXB13_MA1937.2 13 bp overlap
Motif DE_72h DE_72h-ERFHOXB13_MA1937.2 13 bp overlap
ETV1 4 datasets
Motif DE_36h DE_36h-ETV1_MA0761.3 9 bp overlap
Motif DE_48h DE_48h-ETV1_MA0761.3 9 bp overlap
Motif DE_60h DE_60h-ETV1_MA0761.3 9 bp overlap
Motif DE_72h DE_72h-ETV1_MA0761.3 9 bp overlap
ETV5::FOXO1 3 datasets
Motif DE_36h DE_36h-ETV5FOXO1_MA1947.2 10 bp overlap
Motif DE_48h DE_48h-ETV5FOXO1_MA1947.2 10 bp overlap
Motif DE_60h DE_60h-ETV5FOXO1_MA1947.2 10 bp overlap
ETV6 4 datasets
Motif DE_36h DE_36h-ETV6_MA0645.2 9 bp overlap
Motif DE_48h DE_48h-ETV6_MA0645.2 9 bp overlap
Motif DE_60h DE_60h-ETV6_MA0645.2 9 bp overlap
Motif DE_72h DE_72h-ETV6_MA0645.2 9 bp overlap
ETV7 4 datasets
Motif DE_36h DE_36h-ETV7_MA1708.2 9 bp overlap
Motif DE_48h DE_48h-ETV7_MA1708.2 9 bp overlap
Motif DE_60h DE_60h-ETV7_MA1708.2 9 bp overlap
Motif DE_72h DE_72h-ETV7_MA1708.2 9 bp overlap
Elf5 4 datasets
Motif DE_36h DE_36h-Elf5_MA0136.4 8 bp overlap
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap
Motif DE_72h DE_72h-Elf5_MA0136.4 8 bp overlap
Erg 4 datasets
Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap
Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap
Motif DE_60h DE_60h-Erg_MA0474.4 10 bp overlap
Motif DE_72h DE_72h-Erg_MA0474.4 10 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 559 bp overlap
ChIP DE DE-FOXA2-2 382 bp overlap
FOXO1::ELF1 4 datasets
Motif DE_36h DE_36h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 4 datasets
Motif DE_36h DE_36h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXO1::FLI1 4 datasets
Motif DE_36h DE_36h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1FLI1_MA1956.2 13 bp overlap
Foxj3 1 dataset
Motif DE_60h DE_60h-Foxj3_MA0851.2 9 bp overlap
GABPA 4 datasets
Motif DE_36h DE_36h-GABPA_MA0062.4 10 bp overlap
Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap
Motif DE_60h DE_60h-GABPA_MA0062.4 10 bp overlap
Motif DE_72h DE_72h-GABPA_MA0062.4 10 bp overlap
GATA1::TAL1 7 datasets
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 495 bp overlap
ChIP DE DE-GATA4-2 579 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 392 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 322 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 420 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 471 bp overlap
ChIP DE DE-GATA6-2 575 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 295 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 383 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 263 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 297 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 445 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 307 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 351 bp overlap
ChIP foregut GSE117136.GATA6.foregut 369 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 234 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 425 bp overlap
Gli1 4 datasets
Motif DE_36h DE_36h-Gli1_MA1990.2 10 bp overlap
Motif DE_48h DE_48h-Gli1_MA1990.2 10 bp overlap
Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap
Motif DE_72h DE_72h-Gli1_MA1990.2 10 bp overlap
HOXA10 1 dataset
Motif DE_60h DE_60h-HOXA10_MA0899.2 9 bp overlap
HOXB13 1 dataset
Motif DE_60h DE_60h-HOXB13_MA0901.3 9 bp overlap
HOXD9 1 dataset
Motif DE_60h DE_60h-HOXD9_MA0913.3 9 bp overlap
Hoxa13 1 dataset
Motif DE_60h DE_60h-Hoxa13_MA0650.4 8 bp overlap
Hoxd13 1 dataset
Motif DE_60h DE_60h-Hoxd13_MA0909.4 7 bp overlap
IKZF2 4 datasets
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap
Ikzf3 4 datasets
Motif DE_36h DE_36h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_48h DE_48h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_60h DE_60h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_72h DE_72h-Ikzf3_MA1992.2 9 bp overlap
LMO2 1 dataset
ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 176 bp overlap
MEIS1 4 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MXI1 4 datasets
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap
Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap
NCOA3 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 123 bp overlap
Nr2e1 1 dataset
Motif DE_60h DE_60h-Nr2e1_MA0676.1 9 bp overlap
RBPJ 4 datasets
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
SCRT1 4 datasets
Motif DE_36h DE_36h-SCRT1_MA0743.3 10 bp overlap
Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap
Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap
Motif DE_72h DE_72h-SCRT1_MA0743.3 10 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 305 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 589 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 429 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 213 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 174 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 363 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 471 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 468 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 257 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 286 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 159 bp overlap
SOX10 2 datasets
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 273 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 589 bp overlap
SPIB 4 datasets
Motif DE_36h DE_36h-SPIB_MA0081.3 13 bp overlap
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap
Motif DE_72h DE_72h-SPIB_MA0081.3 13 bp overlap
Sox11 2 datasets
Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap
Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap
Spi1 4 datasets
Motif DE_36h DE_36h-Spi1_MA0080.7 13 bp overlap
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap
Motif DE_72h DE_72h-Spi1_MA0080.7 13 bp overlap
Stat2 2 datasets
Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Stat6 4 datasets
Motif DE_36h DE_36h-Stat6_MA0520.2 10 bp overlap
Motif DE_48h DE_48h-Stat6_MA0520.2 10 bp overlap
Motif DE_60h DE_60h-Stat6_MA0520.2 10 bp overlap
Motif DE_72h DE_72h-Stat6_MA0520.2 10 bp overlap
TP63 3 datasets
ChIP SUIT-2 GSE115461.TP63.SUIT-2 355 bp overlap
ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 212 bp overlap
ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 181 bp overlap
Tbx6 1 dataset
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
ZBTB11 4 datasets
Motif DE_36h DE_36h-ZBTB11_MA2329.1 9 bp overlap
Motif DE_48h DE_48h-ZBTB11_MA2329.1 9 bp overlap
Motif DE_60h DE_60h-ZBTB11_MA2329.1 9 bp overlap
Motif DE_72h DE_72h-ZBTB11_MA2329.1 9 bp overlap
ZBTB7A 4 datasets
Motif DE_36h DE_36h-ZBTB7A_MA0750.3 9 bp overlap
Motif DE_48h DE_48h-ZBTB7A_MA0750.3 9 bp overlap
Motif DE_60h DE_60h-ZBTB7A_MA0750.3 9 bp overlap
Motif DE_72h DE_72h-ZBTB7A_MA0750.3 9 bp overlap
ZKSCAN5 4 datasets
Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_72h DE_72h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF175 4 datasets
Motif DE_36h DE_36h-ZNF175_MA2332.1 9 bp overlap
Motif DE_48h DE_48h-ZNF175_MA2332.1 9 bp overlap
Motif DE_60h DE_60h-ZNF175_MA2332.1 9 bp overlap
Motif DE_72h DE_72h-ZNF175_MA2332.1 9 bp overlap
ZNF184 1 dataset
Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap
ZNF189 3 datasets
Motif DE_36h DE_36h-ZNF189_MA1725.2 9 bp overlap
Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
ZNF331 3 datasets
Motif DE_48h DE_48h-ZNF331_MA1726.2 10 bp overlap
Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap
Motif DE_72h DE_72h-ZNF331_MA1726.2 10 bp overlap
ZNF343 4 datasets
Motif DE_36h DE_36h-ZNF343_MA1711.2 16 bp overlap
Motif DE_48h DE_48h-ZNF343_MA1711.2 16 bp overlap
Motif DE_60h DE_60h-ZNF343_MA1711.2 16 bp overlap
Motif DE_72h DE_72h-ZNF343_MA1711.2 16 bp overlap
ZNF354A 1 dataset
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
ZNF418 3 datasets
Motif DE_36h DE_36h-ZNF418_MA1980.1 15 bp overlap
Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap
Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap
ZNF490 1 dataset
ChIP HEK293 GSE76494.ZNF490.HEK293 172 bp overlap
ZNF652 1 dataset
Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap
ZNF708 2 datasets
Motif DE_48h DE_48h-ZNF708_MA1730.2 9 bp overlap
Motif DE_60h DE_60h-ZNF708_MA1730.2 9 bp overlap
Zfp335 2 datasets
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap
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