chr3 : 138,011,772 – 138,012,215
443 bp 68 TFs 1 linked gene
This 443 bp open chromatin element is linked to CLDN18 and is bound by 68 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
CLDN18 1.6 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:138,006,772 – 138,017,215
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
68 transcription factors
Source
Cell type
ATF6 1 dataset
Motif DE_48h DE_48h-ATF6_MA1466.2 13 bp overlap
CHD7 1 dataset
ChIP WA01 ENCSR000AVA.CHD7.WA01 143 bp overlap
CREBBP 1 dataset
ChIP retina_Hu33 GSE137311.CREBBP.retina_Hu33 307 bp overlap
CRX 2 datasets
ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 326 bp overlap
ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 239 bp overlap
CTCF 3 datasets
ChIP retina_Hu22 GSE137311.CTCF.retina_Hu22 269 bp overlap
ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 210 bp overlap
ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 392 bp overlap
CTCF_s 1 dataset
ChIP HeLa-S3_biotin GSE108869.CTCF_s.HeLa-S3_biotin 154 bp overlap
DPRX 2 datasets
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
Dmbx1 2 datasets
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 177 bp overlap
ESR1 5 datasets
Motif DE_48h DE_48h-ESR1_MA0112.4 15 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 124 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 298 bp overlap
ChIP VCaP_E2_ERA GSE43985.ESR1.VCaP_E2_ERA 142 bp overlap
ChIP breast_mrnahist ERP002305.ESR1.breast_mrnahist 123 bp overlap
ESR2 2 datasets
Motif DE_48h DE_48h-ESR2_MA0258.2 15 bp overlap
Motif DE_48h DE_48h-ESR2_MA0258.2 15 bp overlap
ESRRA 3 datasets
Motif DE_48h DE_48h-ESRRA_MA0592.4 9 bp overlap
Motif DE_48h DE_48h-ESRRA_MA0592.4 9 bp overlap
ChIP K-562 ENCSR486IFJ.ESRRA.K-562 424 bp overlap
ESRRB 2 datasets
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 421 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 169 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Esrrg 2 datasets
Motif DE_48h DE_48h-Esrrg_MA0643.2 9 bp overlap
Motif DE_48h DE_48h-Esrrg_MA0643.2 9 bp overlap
FLI1::FOXI1 2 datasets
Motif DE_48h DE_48h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_60h DE_60h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 440 bp overlap
ChIP DE DE-FOXA2-2 443 bp overlap
GATA2 4 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
GATA4 15 datasets
ChIP DE DE-GATA4-1 357 bp overlap
ChIP DE DE-GATA4-2 443 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP G296S GSE85628.GATA4.G296S 217 bp overlap
ChIP G296S_2 GSE85628.GATA4.G296S_2 217 bp overlap
ChIP cardiomyocyte GSE85628.GATA4.cardiomyocyte 206 bp overlap
ChIP cardiomyocyte_1 GSE85628.GATA4.cardiomyocyte_1 207 bp overlap
ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 298 bp overlap
ChIP cardiomyocyte_7 GSE85628.GATA4.cardiomyocyte_7 304 bp overlap
ChIP foregut GSE117136.GATA4.foregut 358 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 431 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 315 bp overlap
GATA5 4 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 18 datasets
ChIP DE DE-GATA6-1 428 bp overlap
ChIP DE DE-GATA6-2 443 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 443 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 443 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 443 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 413 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 443 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 443 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 392 bp overlap
ChIP foregut GSE117136.GATA6.foregut 406 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 372 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 398 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 331 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 287 bp overlap
Gata3 4 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
IKZF1 4 datasets
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap
ChIP K-562 ENCSR395HWC.IKZF1.K-562 376 bp overlap
ChIP K562 ENCFF348IBL 211 bp overlap
JUN 2 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 414 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 428 bp overlap
MEF2C 2 datasets
Motif DE_60h DE_60h-MEF2C_MA0497.2 11 bp overlap
Motif DE_72h DE_72h-MEF2C_MA0497.2 11 bp overlap
MEF2D 2 datasets
ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 338 bp overlap
ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 336 bp overlap
MEIS1 8 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MEIS2 5 datasets
Motif DE_48h DE_48h-MEIS2_MA0774.1 8 bp overlap
Motif DE_60h DE_60h-MEIS2_MA0774.1 8 bp overlap
Motif DE_72h DE_72h-MEIS2_MA0774.1 8 bp overlap
ChIP K-562 ENCSR851BNE.MEIS2.K-562 291 bp overlap
ChIP K562 ENCFF320GSD 153 bp overlap
MEIS3 3 datasets
Motif DE_48h DE_48h-MEIS3_MA0775.2 7 bp overlap
Motif DE_60h DE_60h-MEIS3_MA0775.2 7 bp overlap
Motif DE_72h DE_72h-MEIS3_MA0775.2 7 bp overlap
NKX2-5 2 datasets
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 390 bp overlap
ChIP hESC_sc-14033 GSE89457.NKX2-5.hESC_sc-14033 315 bp overlap
NR2C1 2 datasets
Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap
Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap
NR2C2 5 datasets
Motif DE_48h DE_48h-NR2C2_MA0504.2 14 bp overlap
Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap
Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap
Motif DE_60h DE_60h-NR2C2_MA0504.2 14 bp overlap
Motif DE_72h DE_72h-NR2C2_MA0504.2 14 bp overlap
NR2F1 3 datasets
Motif DE_48h DE_48h-NR2F1_MA1538.1 15 bp overlap
ChIP K-562 ENCSR970NKQ.NR2F1.K-562 443 bp overlap
ChIP K562 ENCFF221HJH 377 bp overlap
NR2F2 2 datasets
Motif DE_48h DE_48h-NR2F2_MA1111.2 7 bp overlap
Motif DE_48h DE_48h-NR2F2_MA1111.2 7 bp overlap
NR2F6 3 datasets
Motif DE_48h DE_48h-NR2F6_MA1539.1 15 bp overlap
ChIP K-562 ENCSR707QWA.NR2F6.K-562 387 bp overlap
ChIP K562 ENCFF674RQA 443 bp overlap
NR4A2 2 datasets
Motif DE_48h DE_48h-NR4A2_MA0160.3 8 bp overlap
Motif DE_48h DE_48h-NR4A2_MA0160.3 8 bp overlap
NR4A2::RXRA 1 dataset
Motif DE_48h DE_48h-NR4A2RXRA_MA1147.2 13 bp overlap
Nr1H2 2 datasets
Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 2 datasets
Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 2 datasets
Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap
OTX2 1 dataset
ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 350 bp overlap
PBX2 2 datasets
ChIP K-562 ENCSR263DFP.PBX2.K-562 225 bp overlap
ChIP K562 ENCFF286KMN 329 bp overlap
PBX3 2 datasets
Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap
Motif DE_60h DE_60h-PBX3_MA1114.2 11 bp overlap
PKNOX1 4 datasets
Motif DE_48h DE_48h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_60h DE_60h-PKNOX1_MA0782.3 10 bp overlap
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 283 bp overlap
ChIP K562 ENCFF236IUS 240 bp overlap
POLR2A 4 datasets
ChIP stomach ENCFF820WZN 104 bp overlap
ChIP stomach ENCFF820WZN 273 bp overlap
ChIP upper lobe of left lung ENCFF199JUI 315 bp overlap
ChIP upper lobe of left lung ENCFF640VPA 266 bp overlap
Ppara 2 datasets
Motif DE_48h DE_48h-Ppara_MA2338.1 7 bp overlap
Motif DE_48h DE_48h-Ppara_MA2338.1 7 bp overlap
RFX1 1 dataset
ChIP K-562 ENCSR968GIB.RFX1.K-562 216 bp overlap
RORB 1 dataset
ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 340 bp overlap
SMAD2-3 4 datasets
ChIP HGrC1_WT GSE138496.SMAD2-3.HGrC1_WT 134 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 443 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 443 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 335 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 344 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 264 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 294 bp overlap
SMARCA4 1 dataset
ChIP 501-mel_SHCTR GSE61965.SMARCA4.501-mel_SHCTR 197 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 295 bp overlap
SOX8 1 dataset
ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 207 bp overlap
SP5 1 dataset
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Six3 3 datasets
Motif DE_48h DE_48h-Six3_MA0631.2 11 bp overlap
Motif DE_60h DE_60h-Six3_MA0631.2 11 bp overlap
Motif DE_72h DE_72h-Six3_MA0631.2 11 bp overlap
TBX5 5 datasets
ChIP G296S GSE85628.TBX5.G296S 251 bp overlap
ChIP G296S_2 GSE85628.TBX5.G296S_2 251 bp overlap
ChIP cardiomyocyte_5 GSE85628.TBX5.cardiomyocyte_5 328 bp overlap
ChIP cardiomyocyte_7 GSE85628.TBX5.cardiomyocyte_7 228 bp overlap
ChIP hiPSC GSE81585.TBX5.hiPSC 288 bp overlap
TRPS1 4 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
VEZF1 2 datasets
ChIP K-562 ENCSR189YMA.VEZF1.K-562 169 bp overlap
ChIP K562 ENCFF053XDV 443 bp overlap
ZNF135 1 dataset
Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap
ZNF148 3 datasets
Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap
Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap
Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap
ZNF281 3 datasets
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF331 1 dataset
Motif DE_48h DE_48h-ZNF331_MA1726.2 10 bp overlap
ZNF460 1 dataset
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
Zic1::Zic2 1 dataset
Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap
Zic2 1 dataset
Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap
Zic3 1 dataset
Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap
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