chr1 : 63,574,025 – 63,574,937
912 bp 44 TFs 8 linked genes
This 912 bp open chromatin element is linked to 8 target genes and is bound by 44 transcription factors.
Linked Genes
8 genes
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PGM1 18.9 kb Distal Multiome
EFCAB7 51.0 kb Distal Multiome
ITGB3BP 51.3 kb Distal Multiome
ROR1 199.5 kb Distal Multiome
ALG6 206.9 kb Distal Multiome
FOXD3 251.9 kb Distal Multiome
FOXD3-AS1 252.1 kb Distal Multiome
AK4 1573.2 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:63,569,025 – 63,579,937
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
44 transcription factors
Source
Cell type
CREB1 1 dataset
ChIP GM23338 ENCFF432ZEW 305 bp overlap
CTCF 2 datasets
ChIP C4-2B ENCFF821XVN 75 bp overlap
ChIP keratinocyte GSE154221.CTCF.keratinocyte 60 bp overlap
EGR2 1 dataset
ChIP HEK293 ENCFF336LFH 425 bp overlap
ETV6 1 dataset
ChIP WTC11 ENCFF812SCD 437 bp overlap
Elf5 1 dataset
Motif ES_0h ES_0h-Elf5_MA0136.4 8 bp overlap
FOXA1 1 dataset
ChIP LNCaP_FENG_shFOXA1_Ethanol GSE128883.FOXA1.LNCaP_FENG_shFOXA1_Ethanol 176 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 473 bp overlap
ChIP DE DE-FOXA2-2 407 bp overlap
FOXP4 1 dataset
ChIP WTC11 ENCFF708TAF 377 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 794 bp overlap
ChIP DE DE-GATA4-2 678 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 365 bp overlap
GATA5 1 dataset
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 658 bp overlap
ChIP DE DE-GATA6-2 626 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 517 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 483 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 537 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 741 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 337 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 410 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 325 bp overlap
ChIP foregut GSE117136.GATA6.foregut 387 bp overlap
Gata3 1 dataset
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
IKZF2 1 dataset
Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap
Irf1 1 dataset
Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap
JUN 1 dataset
ChIP DE_D2 S54-DE-d2-JUN-exp2 275 bp overlap
MEF2A 1 dataset
Motif DE_72h DE_72h-MEF2A_MA0052.5 10 bp overlap
MEF2B 1 dataset
Motif DE_72h DE_72h-MEF2B_MA0660.1 12 bp overlap
MEF2C 1 dataset
Motif DE_72h DE_72h-MEF2C_MA0497.2 11 bp overlap
MEF2D 1 dataset
Motif DE_72h DE_72h-MEF2D_MA0773.1 12 bp overlap
Mecom 1 dataset
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NANOG 10 datasets
ChIP GM23338 ENCFF065NZG 88 bp overlap
ChIP H1 ENCFF747ZPQ 241 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 583 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 238 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 150 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 387 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 197 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 598 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 568 bp overlap
ChIP hESC GSE18292.NANOG.hESC 192 bp overlap
POU1F1 1 dataset
Motif DE_72h DE_72h-POU1F1_MA0784.3 14 bp overlap
POU2F1 1 dataset
Motif DE_72h DE_72h-POU2F1_MA0785.2 9 bp overlap
POU2F2 1 dataset
Motif DE_72h DE_72h-POU2F2_MA0507.3 13 bp overlap
POU3F1 1 dataset
Motif DE_72h DE_72h-POU3F1_MA0786.2 10 bp overlap
POU3F2 1 dataset
Motif DE_72h DE_72h-POU3F2_MA0787.1 12 bp overlap
POU3F3 1 dataset
Motif DE_72h DE_72h-POU3F3_MA0788.1 13 bp overlap
POU3F4 1 dataset
Motif DE_72h DE_72h-POU3F4_MA0789.1 9 bp overlap
POU5F1 1 dataset
ChIP HUES-8 GSE109524.POU5F1.HUES-8 494 bp overlap
POU5F1B 1 dataset
Motif DE_72h DE_72h-POU5F1B_MA0792.1 9 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_72h DE_72h-Pou5f1Sox2_MA0142.1 15 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 353 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 620 bp overlap
STAT1::STAT2 1 dataset
Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap
Sox17 1 dataset
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Sox6 1 dataset
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Sox7 1 dataset
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
TRPS1 1 dataset
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ZFHX2 1 dataset
ChIP HEK293 ENCFF167TUA 268 bp overlap
ZMAT4 1 dataset
ChIP WTC11 ENCFF608UXZ 241 bp overlap
ZNF184 1 dataset
Motif DE_72h DE_72h-ZNF184_MA2120.1 13 bp overlap
ZNF384 1 dataset
Motif DE_72h DE_72h-ZNF384_MA1125.2 8 bp overlap
ZNF418 1 dataset
Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap
ZNF462 1 dataset
ChIP GM23338 ENCFF896CCA 251 bp overlap
Huangfu Lab · Publications · Resources · Contact