chr2 : 221,372,258 – 221,372,441

183 bp 72 TFs 1 linked gene

This 183 bp open chromatin element is linked to ENSG00000290000 and is bound by 72 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000290000		256 bp	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

72 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 91 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 123 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 135 bp overlap

BARX1 1 dataset

Motif DE_12h DE_12h-BARX1_MA0875.2 6 bp overlap

BRD4 2 datasets

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 105 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 163 bp overlap

BSX 1 dataset

Motif DE_12h DE_12h-BSX_MA0876.2 6 bp overlap

CREB1 2 datasets

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 121 bp overlap

ChIP H1 ENCFF955PMP 183 bp overlap

CTCF 12 datasets

ChIP 22Rv1 ENCFF466OXN 83 bp overlap

ChIP C4-2B ENCFF821XVN 138 bp overlap

Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap

ChIP HCT-116 ENCSR240PRQ.CTCF.HCT-116 183 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 166 bp overlap

ChIP PC-3 ENCSR359LOD.CTCF.PC-3 76 bp overlap

ChIP Panc1 ENCFF056JQX 125 bp overlap

ChIP brain ENCFF067KUH 67 bp overlap

ChIP hESC_D5 GSE116862.CTCF.hESC_D5 107 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 92 bp overlap

ChIP hiPSC_parental-line GSE106870.CTCF.hiPSC_parental-line 158 bp overlap

ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 100 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF140EYR 65 bp overlap

ChIP BLaER1 ENCFF274GAT 61 bp overlap

ChIP BLaER1 ENCFF858JKM 82 bp overlap

DLX1 1 dataset

Motif DE_12h DE_12h-DLX1_MA0879.3 6 bp overlap

DLX6 1 dataset

Motif DE_12h DE_12h-DLX6_MA0882.2 6 bp overlap

Dlx2 1 dataset

Motif DE_12h DE_12h-Dlx2_MA0885.3 8 bp overlap

Dlx3 1 dataset

Motif DE_12h DE_12h-Dlx3_MA0880.2 6 bp overlap

Dlx4 1 dataset

Motif DE_12h DE_12h-Dlx4_MA0881.2 6 bp overlap

Dlx5 1 dataset

Motif DE_12h DE_12h-Dlx5_MA1476.3 8 bp overlap

EGR4 2 datasets

Motif DE_12h DE_12h-EGR4_MA0733.2 11 bp overlap

Motif ES_0h ES_0h-EGR4_MA0733.2 11 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 57 bp overlap

ETV5::FOXI1 1 dataset

Motif DE_12h DE_12h-ETV5FOXI1_MA1946.2 12 bp overlap

ETV5::FOXO1 1 dataset

Motif DE_12h DE_12h-ETV5FOXO1_MA1947.2 10 bp overlap

EZH2 1 dataset

ChIP HCT-116 ENCSR046HGP.EZH2.HCT-116 55 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap

GBX2 1 dataset

Motif DE_12h DE_12h-GBX2_MA0890.2 6 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 127 bp overlap

Gfi1B 1 dataset

Motif DE_12h DE_12h-Gfi1B_MA0483.2 10 bp overlap

HESX1 1 dataset

Motif DE_12h DE_12h-HESX1_MA0894.2 6 bp overlap

HMBOX1 1 dataset

Motif DE_12h DE_12h-HMBOX1_MA0895.2 7 bp overlap

HOXA6 1 dataset

Motif DE_12h DE_12h-HOXA6_MA1497.2 7 bp overlap

HOXA7 1 dataset

Motif DE_12h DE_12h-HOXA7_MA1498.3 6 bp overlap

HOXB6 1 dataset

Motif DE_12h DE_12h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif DE_12h DE_12h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif DE_12h DE_12h-HOXB8_MA1502.2 7 bp overlap

HOXD3 1 dataset

Motif DE_12h DE_12h-HOXD3_MA0912.2 8 bp overlap

HOXD8 1 dataset

Motif DE_12h DE_12h-HOXD8_MA0910.3 7 bp overlap

JUN 1 dataset

ChIP HUES-8 GSE109524.JUN.HUES-8 67 bp overlap

LBX2 1 dataset

Motif DE_12h DE_12h-LBX2_MA0699.2 6 bp overlap

LHX2 1 dataset

Motif DE_12h DE_12h-LHX2_MA0700.3 6 bp overlap

MAZ 1 dataset

ChIP HEK293 ENCFF994GSG 55 bp overlap

MED1 1 dataset

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 169 bp overlap

MSX1 1 dataset

Motif DE_12h DE_12h-MSX1_MA0666.3 6 bp overlap

MSX2 1 dataset

Motif DE_12h DE_12h-MSX2_MA0708.3 6 bp overlap

Msx3 1 dataset

Motif DE_12h DE_12h-Msx3_MA0709.2 6 bp overlap

NANOG 5 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 183 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 183 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 122 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 183 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 168 bp overlap

Nobox 1 dataset

Motif DE_12h DE_12h-Nobox_MA0125.2 6 bp overlap

PHIP 2 datasets

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 133 bp overlap

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 183 bp overlap

PHOX2A 1 dataset

Motif DE_12h DE_12h-PHOX2A_MA0713.1 11 bp overlap

POU5F1 4 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 183 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 183 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 144 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 68 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 119 bp overlap

PRDM6 1 dataset

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 62 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 2 datasets

ChIP HEK293_siE1A GSE130135.RAD21.HEK293_siE1A 119 bp overlap

ChIP HEK293_siYAP GSE130135.RAD21.HEK293_siYAP 159 bp overlap

RAX 1 dataset

Motif DE_12h DE_12h-RAX_MA0718.2 6 bp overlap

SMARCA4 3 datasets

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 183 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 140 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 172 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 117 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 183 bp overlap

SOX18 1 dataset

Motif DE_12h DE_12h-SOX18_MA1563.2 8 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 134 bp overlap

SOX8 1 dataset

Motif DE_12h DE_12h-SOX8_MA0868.3 7 bp overlap

SP5 2 datasets

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

SPIC 1 dataset

Motif DE_12h DE_12h-SPIC_MA0687.2 13 bp overlap

SUZ12 1 dataset

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 155 bp overlap

Sox7 1 dataset

Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap

TAF1 1 dataset

ChIP WA01 ENCSR000BHO.TAF1.WA01 130 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 183 bp overlap

ZNF24 1 dataset

Motif DE_12h DE_12h-ZNF24_MA1124.1 13 bp overlap

ZNF257 1 dataset

ChIP HEK293T GSE78099.ZNF257.HEK293T 174 bp overlap

ZNF28 1 dataset

ChIP HEK293T GSE78099.ZNF28.HEK293T 130 bp overlap

ZNF324 1 dataset

ChIP HEK293 ENCSR768HOH.ZNF324.HEK293 58 bp overlap

ZNF335 2 datasets

ChIP HEK293 ENCFF784SLD 54 bp overlap

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 176 bp overlap

ZNF561 1 dataset

ChIP HEK293 ENCSR125ULS.ZNF561.HEK293 94 bp overlap

ZNF660 1 dataset

ChIP HEK293 ENCSR283DOU.ZNF660.HEK293 59 bp overlap

ZNF770 5 datasets

Motif DE_12h DE_12h-ZNF770_MA2099.1 8 bp overlap

Motif ES_0h ES_0h-ZNF770_MA2099.1 8 bp overlap

ChIP HEK293 ENCFF468FCG 183 bp overlap

ChIP HEK293 GSE76494.ZNF770.HEK293 116 bp overlap

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 183 bp overlap

ZSCAN21 1 dataset

Motif DE_12h DE_12h-ZSCAN21_MA2336.1 7 bp overlap

Zbtb2 1 dataset

Motif DE_12h DE_12h-Zbtb2_MA2340.1 10 bp overlap