chr2 : 162,066,557 – 162,067,072

515 bp 58 TFs 2 linked genes

This 515 bp open chromatin element is linked to DPP4-DT and DPP4 and is bound by 58 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
DPP4-DT		6.4 kb	Proximal	Proximity
DPP4		7.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

58 transcription factors

ATF4 1 dataset

Motif DE_36h DE_36h-ATF4_MA0833.3 10 bp overlap

Arid3a 2 datasets

Motif DE_12h DE_12h-Arid3a_MA0151.1 6 bp overlap

Motif DE_36h DE_36h-Arid3a_MA0151.1 6 bp overlap

Ascl2 2 datasets

Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap

Motif DE_36h DE_36h-Ascl2_MA0816.1 10 bp overlap

BHLHE22 2 datasets

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

Motif DE_36h DE_36h-BHLHE22_MA1635.2 6 bp overlap

BRD4 2 datasets

ChIP LNCaP-C4-2_F133V_JQ1 GSE88871.BRD4.LNCaP-C4-2_F133V_JQ1 86 bp overlap

ChIP LNCaP-C4-2_OE GSE88871.BRD4.LNCaP-C4-2_OE 212 bp overlap

CEBPG 1 dataset

Motif DE_36h DE_36h-CEBPG_MA1636.2 10 bp overlap

EWSR1-FLI1 2 datasets

Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap

FERD3L 2 datasets

Motif DE_12h DE_12h-FERD3L_MA1485.1 14 bp overlap

Motif DE_36h DE_36h-FERD3L_MA1485.1 14 bp overlap

GATA6 3 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 306 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 270 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 281 bp overlap

Hic1 1 dataset

Motif DE_36h DE_36h-Hic1_MA0739.2 8 bp overlap

IRF3 2 datasets

Motif DE_12h DE_12h-IRF3_MA1418.2 17 bp overlap

Motif DE_36h DE_36h-IRF3_MA1418.2 17 bp overlap

Isl1 2 datasets

Motif DE_12h DE_12h-Isl1_MA1608.2 7 bp overlap

Motif DE_36h DE_36h-Isl1_MA1608.2 7 bp overlap

MAZ 1 dataset

Motif DE_36h DE_36h-MAZ_MA1522.2 8 bp overlap

MSANTD3 2 datasets

Motif DE_12h DE_12h-MSANTD3_MA1523.2 7 bp overlap

Motif DE_36h DE_36h-MSANTD3_MA1523.2 7 bp overlap

MSC 2 datasets

Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap

Motif DE_36h DE_36h-MSC_MA0665.1 10 bp overlap

MXI1 2 datasets

Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap

MYF6 2 datasets

Motif DE_12h DE_12h-MYF6_MA0667.1 10 bp overlap

Motif DE_36h DE_36h-MYF6_MA0667.1 10 bp overlap

NKX6-3 2 datasets

Motif DE_12h DE_12h-NKX6-3_MA1530.2 8 bp overlap

Motif DE_36h DE_36h-NKX6-3_MA1530.2 8 bp overlap

Neurod2 2 datasets

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

Motif DE_36h DE_36h-Neurod2_MA1993.2 6 bp overlap

Nr2f6 1 dataset

Motif DE_36h DE_36h-Nr2f6_MA0677.2 13 bp overlap

Olig2 2 datasets

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

Motif DE_36h DE_36h-Olig2_MA1997.2 6 bp overlap

PHOX2B 1 dataset

Motif DE_36h DE_36h-PHOX2B_MA0681.3 12 bp overlap

POU1F1 2 datasets

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

Motif DE_36h DE_36h-POU1F1_MA0784.3 14 bp overlap

POU2F1 2 datasets

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

Motif DE_36h DE_36h-POU2F1_MA0785.2 9 bp overlap

POU2F3 2 datasets

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

Motif DE_36h DE_36h-POU2F3_MA0627.3 9 bp overlap

POU3F1 2 datasets

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

Motif DE_36h DE_36h-POU3F1_MA0786.2 10 bp overlap

POU3F3 2 datasets

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

Motif DE_36h DE_36h-POU3F3_MA0788.1 13 bp overlap

POU3F4 2 datasets

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

Motif DE_36h DE_36h-POU3F4_MA0789.1 9 bp overlap

POU5F1B 2 datasets

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

Motif DE_36h DE_36h-POU5F1B_MA0792.1 9 bp overlap

PPARD 1 dataset

Motif DE_36h DE_36h-PPARD_MA1550.2 14 bp overlap

PRDM1 1 dataset

Motif DE_36h DE_36h-PRDM1_MA0508.4 7 bp overlap

Ptf1A 2 datasets

Motif DE_12h DE_12h-Ptf1A_MA1619.2 8 bp overlap

Motif DE_36h DE_36h-Ptf1A_MA1619.2 8 bp overlap

RUNX1 1 dataset

ChIP VCaP_DHT24H GSE58428.RUNX1.VCaP_DHT24H 348 bp overlap

RUNX3 1 dataset

Motif DE_36h DE_36h-RUNX3_MA0684.3 8 bp overlap

RXRB 1 dataset

Motif DE_36h DE_36h-RXRB_MA0855.1 14 bp overlap

RXRG 1 dataset

Motif DE_36h DE_36h-RXRG_MA0856.1 14 bp overlap

Rfx6 2 datasets

Motif DE_12h DE_12h-Rfx6_MA1724.2 9 bp overlap

Motif DE_36h DE_36h-Rfx6_MA1724.2 9 bp overlap

Rxra 1 dataset

Motif DE_36h DE_36h-Rxra_MA0512.2 14 bp overlap

SIX2 1 dataset

Motif DE_36h DE_36h-SIX2_MA1119.2 11 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 331 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 252 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 324 bp overlap

SP5 5 datasets

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

SREBF1 2 datasets

Motif DE_12h DE_12h-SREBF1_MA0829.3 10 bp overlap

Motif DE_36h DE_36h-SREBF1_MA0829.3 10 bp overlap

TEAD1 1 dataset

Motif DE_36h DE_36h-TEAD1_MA0090.4 9 bp overlap

TFAP4 3 datasets

Motif DE_12h DE_12h-TFAP4_MA0691.1 10 bp overlap

Motif DE_36h DE_36h-TFAP4_MA0691.1 10 bp overlap

Motif DE_36h DE_36h-TFAP4_MA1570.1 10 bp overlap

TFAP4::FLI1 2 datasets

Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap

Motif DE_36h DE_36h-TFAP4FLI1_MA1967.2 14 bp overlap

Tbx6 1 dataset

Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap

Tcf12 2 datasets

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Motif DE_36h DE_36h-Tcf12_MA0521.3 6 bp overlap

Tcf21 2 datasets

Motif DE_12h DE_12h-Tcf21_MA0832.2 10 bp overlap

Motif DE_36h DE_36h-Tcf21_MA0832.2 10 bp overlap

Twist2 2 datasets

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

Motif DE_36h DE_36h-Twist2_MA0633.3 6 bp overlap

USF1 1 dataset

Motif DE_36h DE_36h-USF1_MA0093.4 10 bp overlap

VDR 1 dataset

ChIP kidney-cortex GSE129585.VDR.kidney-cortex 310 bp overlap

Wt1 2 datasets

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap

ZKSCAN5 2 datasets

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF274 2 datasets

Motif DE_12h DE_12h-ZNF274_MA1592.2 12 bp overlap

Motif DE_36h DE_36h-ZNF274_MA1592.2 12 bp overlap

ZNF317 2 datasets

Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap

Motif DE_36h DE_36h-ZNF317_MA1593.2 8 bp overlap

ZNF770 1 dataset

Motif DE_36h DE_36h-ZNF770_MA2099.1 8 bp overlap

Zfx 2 datasets

Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap

Motif DE_36h DE_36h-Zfx_MA0146.3 10 bp overlap