chr2:86,172,557–86,173,357

chr2 : 86,172,557 – 86,173,357

800 bp 74 TFs 6 linked genes

This 800 bp open chromatin element is linked to 6 target genes and is bound by 74 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
IMMT		22.7 kb	Distal	Multiome
MRPL35		26.6 kb	Distal	Multiome
PTCD3		66.6 kb	Distal	Multiome
POLR1A		66.9 kb	Distal	Multiome
KDM3A		268.6 kb	Distal	Multiome
ST3GAL5		283.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 118 bp overlap

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

DPRX 2 datasets

Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap

Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap

Dmbx1 2 datasets

Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap

Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap

Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 293 bp overlap

ETV5::FOXO1 2 datasets

Motif DE_60h DE_60h-ETV5FOXO1_MA1947.2 10 bp overlap

Motif DE_72h DE_72h-ETV5FOXO1_MA1947.2 10 bp overlap

FOXA1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 254 bp overlap

FOXA2 4 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 215 bp overlap

ChIP Caco-2 GSE66218.FOXA2.Caco-2 103 bp overlap

ChIP DE DE-FOXA2-1 461 bp overlap

ChIP DE DE-FOXA2-2 453 bp overlap

GATA1 3 datasets

Motif DE_60h DE_60h-GATA1_MA0035.5 7 bp overlap

Motif DE_72h DE_72h-GATA1_MA0035.5 7 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 169 bp overlap

GATA2 3 datasets

Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 284 bp overlap

GATA3 1 dataset

ChIP SH-SY5Y ENCSR000EXZ.GATA3.SH-SY5Y 251 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 197 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 541 bp overlap

ChIP DE DE-GATA4-2 655 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 433 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 507 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 460 bp overlap

GATA5 2 datasets

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 19 datasets

ChIP AGS GSE51705.GATA6.AGS 175 bp overlap

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 271 bp overlap

ChIP DE DE-GATA6-1 490 bp overlap

ChIP DE DE-GATA6-2 626 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 350 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 378 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 387 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 585 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 409 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 397 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 208 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 526 bp overlap

ChIP foregut GSE117136.GATA6.foregut 452 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 305 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 451 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 410 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 419 bp overlap

GLIS2 1 dataset

Motif DE_72h DE_72h-GLIS2_MA0736.1 14 bp overlap

GLIS3 1 dataset

Motif DE_72h DE_72h-GLIS3_MA0737.1 14 bp overlap

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

GSC2 2 datasets

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

Gata3 2 datasets

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HDAC2 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 56 bp overlap

INSM1 2 datasets

Motif DE_60h DE_60h-INSM1_MA0155.1 12 bp overlap

Motif DE_72h DE_72h-INSM1_MA0155.1 12 bp overlap

Motif DE_72h DE_72h-IRF2_MA0051.2 16 bp overlap

JUN::JUNB 2 datasets

Motif DE_60h DE_60h-JUNJUNB_MA1132.2 8 bp overlap

Motif DE_72h DE_72h-JUNJUNB_MA1132.2 8 bp overlap

KDM1A 2 datasets

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 173 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 194 bp overlap

LIN54 1 dataset

Motif DE_72h DE_72h-LIN54_MA0619.2 7 bp overlap

NR4A1 1 dataset

Motif DE_60h DE_60h-NR4A1_MA1112.3 8 bp overlap

NR4A2 1 dataset

Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap

OTX1 2 datasets

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

PBX2 2 datasets

Motif DE_60h DE_60h-PBX2_MA1113.3 9 bp overlap

Motif DE_72h DE_72h-PBX2_MA1113.3 9 bp overlap

PITX1 2 datasets

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX2 2 datasets

Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap

Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap

PITX3 2 datasets

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

POU5F1 2 datasets

Motif DE_60h DE_60h-POU5F1_MA1115.2 7 bp overlap

Motif DE_72h DE_72h-POU5F1_MA1115.2 7 bp overlap

RHOXF1 2 datasets

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

SIX2 2 datasets

ChIP HEK GSE73865.SIX2.HEK 442 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 366 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 589 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 408 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 105 bp overlap

SOX10 1 dataset

Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap

SOX17_M 2 datasets

ChIP DE_D2 DED2-SOX17-M_Batch_II 428 bp overlap

ChIP DE_D2 DED2-SOX17-M_Batch_II 91 bp overlap

Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Sox11 1 dataset

Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap

Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap

Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap

Stat5a::Stat5b 2 datasets

Motif DE_60h DE_60h-Stat5aStat5b_MA0519.2 9 bp overlap

Motif DE_72h DE_72h-Stat5aStat5b_MA0519.2 9 bp overlap

TCF7L1 1 dataset

Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap

TEAD1 1 dataset

Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap

TEAD2 1 dataset

Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap

TEAD3 1 dataset

Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap

TEAD4 1 dataset

Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap

THRA 3 datasets

Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap

Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap

Motif DE_72h DE_72h-THRA_MA1969.2 18 bp overlap

ChIP HCT-116_Nutlin3a GSE125927.TP53.HCT-116_Nutlin3a 145 bp overlap

TRPS1 2 datasets

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

VEZF1 2 datasets

Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap

Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap

Motif DE_72h DE_72h-Wt1_MA1627.2 10 bp overlap

ChIP MCF-7 GSE102616.ZFX.MCF-7 59 bp overlap

ZNF121 1 dataset

ChIP HepG2 ENCFF343YSL 194 bp overlap

ZNF157 1 dataset

Motif DE_72h DE_72h-ZNF157_MA2331.1 21 bp overlap

ZNF189 2 datasets

Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap

Motif DE_72h DE_72h-ZNF189_MA1725.2 9 bp overlap

ZNF213 2 datasets

Motif DE_60h DE_60h-ZNF213_MA2121.1 12 bp overlap

Motif DE_72h DE_72h-ZNF213_MA2121.1 12 bp overlap

ZNF282 2 datasets

Motif DE_60h DE_60h-ZNF282_MA1154.2 15 bp overlap

Motif DE_72h DE_72h-ZNF282_MA1154.2 15 bp overlap

ZNF410 1 dataset

Motif DE_72h DE_72h-ZNF410_MA0752.2 16 bp overlap

ZNF416 2 datasets

Motif DE_60h DE_60h-ZNF416_MA1979.2 10 bp overlap

Motif DE_72h DE_72h-ZNF416_MA1979.2 10 bp overlap

ZNF528 2 datasets

Motif DE_60h DE_60h-ZNF528_MA1597.1 17 bp overlap

Motif DE_72h DE_72h-ZNF528_MA1597.1 17 bp overlap

ZNF547 2 datasets

Motif DE_60h DE_60h-ZNF547_MA2334.1 13 bp overlap

Motif DE_72h DE_72h-ZNF547_MA2334.1 13 bp overlap

ZNF549 2 datasets

Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap

Motif DE_72h DE_72h-ZNF549_MA1728.2 8 bp overlap

ZNF652 2 datasets

Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap

Motif DE_72h DE_72h-ZNF652_MA1657.2 9 bp overlap

ZNF85 1 dataset

Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap

Zfp809 2 datasets

Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap

Zic1::Zic2 2 datasets

Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Zic3 2 datasets

Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap