Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

45 transcription factors

CEBPA 1 dataset

ChIP T-47D_siCtrl GSE132649.CEBPA.T-47D_siCtrl 107 bp overlap

CEBPB 2 datasets

ChIP A549 ENCFF797MXZ 87 bp overlap

ChIP K562 ENCFF584CTB 162 bp overlap

CEBPG 1 dataset

ChIP K-562 ENCSR490LWA.CEBPG.K-562 55 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 201 bp overlap

Cebpa 7 datasets

ChIP BLaER1 ENCFF093OYK 295 bp overlap

ChIP BLaER1 ENCFF274GAT 189 bp overlap

ChIP BLaER1 ENCFF274GAT 191 bp overlap

ChIP BLaER1 ENCFF335XTP 311 bp overlap

ChIP BLaER1 ENCFF346MCV 163 bp overlap

ChIP BLaER1 ENCFF364PUR 252 bp overlap

ChIP BLaER1 ENCFF844FIP 145 bp overlap

EED 1 dataset

ChIP ProEs GSE59087.EED.ProEs 174 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 192 bp overlap

ESR1 2 datasets

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 243 bp overlap

ChIP breast_tumor_BADOUTCOME GSE40867.ESR1.breast_tumor_BADOUTCOME 192 bp overlap

ETV5::DRGX 1 dataset

Motif DE_60h DE_60h-ETV5DRGX_MA1944.2 12 bp overlap

EZH2 1 dataset

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 106 bp overlap

FOS 1 dataset

ChIP MCF-7 ENCFF282FWZ 102 bp overlap

FOXA1 3 datasets

ChIP T-47D_shRNF2_45min GSE137579.FOXA1.T-47D_shRNF2_45min 144 bp overlap

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 285 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 270 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 491 bp overlap

ChIP DE DE-FOXA2-2 398 bp overlap

GATA2 3 datasets

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 305 bp overlap

ChIP primary-endometrial-stromal-cell_IVD_P1 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P1 56 bp overlap

ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 60 bp overlap

GATA3 2 datasets

ChIP MCF-7 ENCFF352QVM 124 bp overlap

ChIP MCF-7 ENCFF437NQS 92 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 675 bp overlap

ChIP DE DE-GATA4-2 675 bp overlap

ChIP foregut GSE117136.GATA4.foregut 625 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 675 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 590 bp overlap

GATA6 14 datasets

ChIP DE DE-GATA6-1 670 bp overlap

ChIP DE DE-GATA6-2 675 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 663 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 675 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 592 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 675 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 675 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 663 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 589 bp overlap

ChIP foregut GSE117136.GATA6.foregut 646 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 675 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 675 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 675 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 583 bp overlap

HNF4A 1 dataset

ChIP liver ENCFF354NRH 164 bp overlap

Hmx1 1 dataset

Motif DE_60h DE_60h-Hmx1_MA0896.2 9 bp overlap

Hmx2 1 dataset

Motif DE_60h DE_60h-Hmx2_MA0897.2 15 bp overlap

Hmx3 1 dataset

Motif DE_60h DE_60h-Hmx3_MA0898.2 9 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 224 bp overlap

MEIS1 1 dataset

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

Nanog 1 dataset

Motif DE_60h DE_60h-Nanog_MA2339.1 7 bp overlap

ONECUT1 2 datasets

Motif DE_60h DE_60h-ONECUT1_MA0679.3 9 bp overlap

ChIP liver ERP002306.ONECUT1.liver 71 bp overlap

PDX1 4 datasets

ChIP hESC GSE58685.PDX1.hESC 237 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 340 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 323 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 675 bp overlap

PKNOX1 1 dataset

ChIP MCF-7 ENCSR986XYK.PKNOX1.MCF-7 163 bp overlap

POU4F1 1 dataset

Motif DE_60h DE_60h-POU4F1_MA0790.2 12 bp overlap

POU4F2 1 dataset

Motif DE_60h DE_60h-POU4F2_MA0683.2 15 bp overlap

POU4F3 1 dataset

Motif DE_60h DE_60h-POU4F3_MA0791.2 12 bp overlap

Pax7 1 dataset

Motif DE_60h DE_60h-Pax7_MA0680.3 10 bp overlap

RARA 4 datasets

ChIP hiPSC_D2 GSE132532.RARA.hiPSC_D2 185 bp overlap

ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 334 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 397 bp overlap

ChIP hiPSC_D5 GSE132532.RARA.hiPSC_D5 376 bp overlap

RCOR1 1 dataset

ChIP keratinocyte_diff GSE57702.RCOR1.keratinocyte_diff 131 bp overlap

RREB1 1 dataset

Motif DE_60h DE_60h-RREB1_MA0073.2 19 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 601 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 675 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 406 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 675 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 272 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 658 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 446 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 132 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 218 bp overlap

SNAI2 2 datasets

ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 375 bp overlap

ChIP SMS-CTR_shSNAI2 GSE137168.SNAI2.SMS-CTR_shSNAI2 334 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 223 bp overlap

SP1 1 dataset

ChIP liver ENCFF597LFJ 108 bp overlap

ZBTB17 1 dataset

Motif DE_60h DE_60h-ZBTB17_MA2102.1 8 bp overlap

ZNF317 1 dataset

Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap

ZNF667 1 dataset

Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap

ZNF750 1 dataset

ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 174 bp overlap

Gene	Dist. to TSS	Distance	Link type
ST8SIA1	4.4 kb	Proximal	Proximity
CMAS	199.8 kb	Distal	Multiome
C2CD5	298.1 kb	Distal	Multiome
C2CD5-AS1	298.5 kb	Distal	Multiome

Genome Browser