chr10 : 113,289,821 – 113,290,535
714 bp 70 TFs 1 linked gene
This 714 bp open chromatin element is linked to TCF7L2 and is bound by 70 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TCF7L2 340.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr10:113,284,821 – 113,295,535
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
70 transcription factors
Source
Cell type
ATF4 3 datasets
Motif DE_48h DE_48h-ATF4_MA0833.3 10 bp overlap
Motif DE_60h DE_60h-ATF4_MA0833.3 10 bp overlap
Motif DE_72h DE_72h-ATF4_MA0833.3 10 bp overlap
Bcl11B 2 datasets
Motif DE_60h DE_60h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_72h DE_72h-Bcl11B_MA1989.2 9 bp overlap
CEBPA 1 dataset
ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.CEBPA.Kasumi-1_CEBPA-ER_E2 57 bp overlap
CEBPG 3 datasets
Motif DE_48h DE_48h-CEBPG_MA1636.2 10 bp overlap
Motif DE_60h DE_60h-CEBPG_MA1636.2 10 bp overlap
Motif DE_72h DE_72h-CEBPG_MA1636.2 10 bp overlap
Crx 2 datasets
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
DMRTA2 2 datasets
Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_72h DE_72h-DMRTA2_MA1478.2 6 bp overlap
DPRX 1 dataset
Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap
DUX4 3 datasets
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap
DUXA 3 datasets
Motif DE_48h DE_48h-DUXA_MA0884.2 13 bp overlap
Motif DE_60h DE_60h-DUXA_MA0884.2 13 bp overlap
Motif DE_72h DE_72h-DUXA_MA0884.2 13 bp overlap
Dux 3 datasets
Motif DE_48h DE_48h-Dux_MA0611.3 11 bp overlap
Motif DE_60h DE_60h-Dux_MA0611.3 11 bp overlap
Motif DE_72h DE_72h-Dux_MA0611.3 11 bp overlap
E2F6 3 datasets
Motif DE_48h DE_48h-E2F6_MA0471.3 8 bp overlap
Motif DE_60h DE_60h-E2F6_MA0471.3 8 bp overlap
Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 249 bp overlap
ERF::FOXO1 2 datasets
Motif DE_36h DE_36h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_72h DE_72h-ERFFOXO1_MA1936.2 12 bp overlap
ETV2::FIGLA 3 datasets
Motif DE_48h DE_48h-ETV2FIGLA_MA1941.2 13 bp overlap
Motif DE_60h DE_60h-ETV2FIGLA_MA1941.2 13 bp overlap
Motif DE_72h DE_72h-ETV2FIGLA_MA1941.2 13 bp overlap
ETV5::DRGX 3 datasets
Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_60h DE_60h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_72h DE_72h-ETV5DRGX_MA1944.2 12 bp overlap
ETV5::FIGLA 3 datasets
Motif DE_48h DE_48h-ETV5FIGLA_MA1945.2 14 bp overlap
Motif DE_60h DE_60h-ETV5FIGLA_MA1945.2 14 bp overlap
Motif DE_72h DE_72h-ETV5FIGLA_MA1945.2 14 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
FIGLA 3 datasets
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 295 bp overlap
ChIP DE DE-FOXA2-2 345 bp overlap
GATA1::TAL1 3 datasets
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 2 datasets
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 714 bp overlap
ChIP DE DE-GATA4-2 714 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 663 bp overlap
GATA5 2 datasets
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 551 bp overlap
ChIP DE DE-GATA6-2 714 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 592 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 475 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 381 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 675 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 551 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 593 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 523 bp overlap
ChIP foregut GSE117136.GATA6.foregut 360 bp overlap
GFI1 3 datasets
Motif DE_48h DE_48h-GFI1_MA0038.3 11 bp overlap
Motif DE_60h DE_60h-GFI1_MA0038.3 11 bp overlap
Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap
GSC 2 datasets
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 2 datasets
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gata3 2 datasets
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HOXB13 1 dataset
Motif DE_72h DE_72h-HOXB13_MA0901.3 9 bp overlap
HOXC13 1 dataset
Motif DE_72h DE_72h-HOXC13_MA0907.2 9 bp overlap
JUN 4 datasets
Motif DE_48h DE_48h-JUN_MA0488.2 10 bp overlap
Motif DE_60h DE_60h-JUN_MA0488.2 10 bp overlap
Motif DE_72h DE_72h-JUN_MA0488.2 10 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 320 bp overlap
MSANTD3 3 datasets
Motif DE_48h DE_48h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_60h DE_60h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_72h DE_72h-MSANTD3_MA1523.2 7 bp overlap
MZF1 3 datasets
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap
Mecom 2 datasets
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NFYA 3 datasets
Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap
Motif DE_60h DE_60h-NFYA_MA0060.4 8 bp overlap
Motif DE_72h DE_72h-NFYA_MA0060.4 8 bp overlap
NFYC 3 datasets
Motif DE_48h DE_48h-NFYC_MA1644.2 7 bp overlap
Motif DE_60h DE_60h-NFYC_MA1644.2 7 bp overlap
Motif DE_72h DE_72h-NFYC_MA1644.2 7 bp overlap
OTX1 2 datasets
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
OTX2 2 datasets
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap
PITX1 2 datasets
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX2 2 datasets
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap
PITX3 2 datasets
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
Ptf1A 3 datasets
Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap
RBPJ 4 datasets
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
RFX1 3 datasets
Motif DE_48h DE_48h-RFX1_MA0509.3 16 bp overlap
Motif DE_60h DE_60h-RFX1_MA0509.3 16 bp overlap
Motif DE_72h DE_72h-RFX1_MA0509.3 16 bp overlap
RFX2 3 datasets
Motif DE_48h DE_48h-RFX2_MA0600.3 14 bp overlap
Motif DE_60h DE_60h-RFX2_MA0600.3 14 bp overlap
Motif DE_72h DE_72h-RFX2_MA0600.3 14 bp overlap
RFX3 3 datasets
Motif DE_48h DE_48h-RFX3_MA0798.3 16 bp overlap
Motif DE_60h DE_60h-RFX3_MA0798.3 16 bp overlap
Motif DE_72h DE_72h-RFX3_MA0798.3 16 bp overlap
RFX5 3 datasets
Motif DE_48h DE_48h-RFX5_MA0510.3 14 bp overlap
Motif DE_60h DE_60h-RFX5_MA0510.3 14 bp overlap
Motif DE_72h DE_72h-RFX5_MA0510.3 14 bp overlap
RHOXF1 2 datasets
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 349 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 318 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 443 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 259 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 428 bp overlap
Stat6 2 datasets
Motif DE_36h DE_36h-Stat6_MA0520.2 10 bp overlap
Motif DE_72h DE_72h-Stat6_MA0520.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap
TBP 1 dataset
Motif DE_72h DE_72h-TBP_MA0108.3 7 bp overlap
TFAP4::ETV1 3 datasets
Motif DE_48h DE_48h-TFAP4ETV1_MA1966.2 13 bp overlap
Motif DE_60h DE_60h-TFAP4ETV1_MA1966.2 13 bp overlap
Motif DE_72h DE_72h-TFAP4ETV1_MA1966.2 13 bp overlap
TRPS1 2 datasets
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ZEB1 3 datasets
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZKSCAN5 3 datasets
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_72h DE_72h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF189 3 datasets
Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
Motif DE_72h DE_72h-ZNF189_MA1725.2 9 bp overlap
ZNF274 3 datasets
Motif DE_48h DE_48h-ZNF274_MA1592.2 12 bp overlap
Motif DE_60h DE_60h-ZNF274_MA1592.2 12 bp overlap
Motif DE_72h DE_72h-ZNF274_MA1592.2 12 bp overlap
ZNF282 2 datasets
Motif DE_36h DE_36h-ZNF282_MA1154.2 15 bp overlap
Motif DE_72h DE_72h-ZNF282_MA1154.2 15 bp overlap
ZNF341 3 datasets
Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap
Motif DE_60h DE_60h-ZNF341_MA1655.2 8 bp overlap
Motif DE_72h DE_72h-ZNF341_MA1655.2 8 bp overlap
ZNF449 2 datasets
Motif DE_36h DE_36h-ZNF449_MA1656.2 10 bp overlap
Motif DE_72h DE_72h-ZNF449_MA1656.2 10 bp overlap
ZNF664 2 datasets
ChIP HEK293 ENCFF343XSW 342 bp overlap
ChIP HEK293 ENCSR714LZQ.ZNF664.HEK293 292 bp overlap
ZNF736 1 dataset
ChIP HEK293T GSE78099.ZNF736.HEK293T 102 bp overlap
ZNF75D 3 datasets
Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_60h DE_60h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_72h DE_72h-ZNF75D_MA1601.2 12 bp overlap
ZNF766 3 datasets
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap
Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap
ZSCAN5C 1 dataset
ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 194 bp overlap
Zfp335 2 datasets
Motif DE_36h DE_36h-Zfp335_MA2002.2 7 bp overlap
Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap
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