chr8 : 67,950,564 – 67,951,116

552 bp 59 TFs 1 linked gene

This 552 bp open chromatin element is linked to PREX2 and is bound by 59 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PREX2		928 bp	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

59 transcription factors

Arid3a 1 dataset

Motif DE_12h DE_12h-Arid3a_MA0151.1 6 bp overlap

BCOR 1 dataset

ChIP WA01 GSE104690.BCOR.WA01 282 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 350 bp overlap

CTCF 1 dataset

Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

ETV6 1 dataset

ChIP WTC11 ENCFF812SCD 365 bp overlap

EZH2 2 datasets

ChIP A-1847 GSE95643.EZH2.A-1847 450 bp overlap

ChIP A-673 ENCSR179SAO.EZH2.A-673 346 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 552 bp overlap

ChIP DE DE-FOXA2-2 552 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 201 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 335 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 284 bp overlap

ChIP DE DE-GATA4-2 362 bp overlap

ChIP DE DE-GATA4-2 56 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 241 bp overlap

ChIP DE DE-GATA6-1 63 bp overlap

ChIP DE DE-GATA6-2 536 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 83 bp overlap

Gli1 1 dataset

Motif DE_12h DE_12h-Gli1_MA1990.2 10 bp overlap

HNF4A 1 dataset

Motif DE_12h DE_12h-HNF4A_MA1494.2 14 bp overlap

Hnf1A 1 dataset

Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap

MGA 1 dataset

Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap

NANOG 10 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 192 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 552 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 336 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 552 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 552 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 552 bp overlap

ChIP hESC GSE18292.NANOG.hESC 265 bp overlap

ChIP hESC GSE20650.NANOG.hESC 169 bp overlap

ChIP hESC GSE18292.NANOG.hESC 93 bp overlap

NIPBL 2 datasets

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 196 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 251 bp overlap

NR4A1 1 dataset

Motif DE_12h DE_12h-NR4A1_MA1112.3 8 bp overlap

NR4A2 1 dataset

Motif DE_12h DE_12h-NR4A2_MA0160.3 8 bp overlap

PCGF2 1 dataset

ChIP fibroblast_MET GSE55605.PCGF2.fibroblast_MET 104 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 115 bp overlap

POU5F1 2 datasets

ChIP GM23338 ENCFF333SNB 299 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 133 bp overlap

PROX1 1 dataset

ChIP SW480 GSE60390.PROX1.SW480 85 bp overlap

Pparg::Rxra 1 dataset

Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap

RING1 1 dataset

ChIP SYO-1_shRING1A-B GSE139053.RING1.SYO-1_shRING1A-B 353 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 228 bp overlap

SMAD1 1 dataset

ChIP BG03 GSE36578.SMAD1.BG03 96 bp overlap

SMARCA4 5 datasets

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 361 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 300 bp overlap

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 235 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 375 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 340 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 286 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 316 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 539 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 540 bp overlap

SOX10 1 dataset

Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 208 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 233 bp overlap

SOX2 3 datasets

ChIP HNSC GSE69479.SOX2.HNSC 256 bp overlap

ChIP hESC GSE18292.SOX2.hESC 97 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 353 bp overlap

SOX4 1 dataset

Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap

SP1 1 dataset

ChIP WTC11 ENCFF688PEU 410 bp overlap

SS18 1 dataset

ChIP SYO-1_shRING1A-B GSE139053.SS18.SYO-1_shRING1A-B 172 bp overlap

Sox11 1 dataset

Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap

Sox5 1 dataset

Motif DE_12h DE_12h-Sox5_MA0087.3 8 bp overlap

Sox6 1 dataset

Motif DE_12h DE_12h-Sox6_MA0515.1 10 bp overlap

Sox7 1 dataset

Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 185 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TBX5 1 dataset

Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap

TCF7L1 1 dataset

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 1 dataset

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

TP53 1 dataset

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 319 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

ZNF283 1 dataset

ChIP HEK293T GSE78099.ZNF283.HEK293T 173 bp overlap

ZNF75D 1 dataset

Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap