chr8 : 17,502,125 – 17,502,356
231 bp 46 TFs 1 linked gene
This 231 bp open chromatin element is linked to SLC7A2 and is bound by 46 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SLC7A2 5.0 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:17,497,125 – 17,507,356
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
46 transcription factors
Source
Cell type
AHR 1 dataset
ChIP MCF-7_TCDD_45min GSE90550.AHR.MCF-7_TCDD_45min 151 bp overlap
AR 1 dataset
ChIP MCF-7 ERP001226.AR.MCF-7 194 bp overlap
ARID1A 4 datasets
ChIP MCF-7 GSE123284.ARID1A.MCF-7 158 bp overlap
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 231 bp overlap
ChIP MCF-7_DCDT GSE123284.ARID1A.MCF-7_DCDT 204 bp overlap
ChIP MCF-7_Fulvestrant GSE123284.ARID1A.MCF-7_Fulvestrant 175 bp overlap
BRD4 1 dataset
ChIP HEK293T GSE51633.BRD4.HEK293T 126 bp overlap
CREBBP 1 dataset
ChIP MCF-7 ERP000901.CREBBP.MCF-7 157 bp overlap
DPF2 1 dataset
ChIP MCF-7 ENCSR234VCE.DPF2.MCF-7 133 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 191 bp overlap
ESR1 47 datasets
ChIP MCF-7 GSE117492.ESR1.MCF-7 231 bp overlap
ChIP MCF-7 GSE128445.ESR1.MCF-7 194 bp overlap
ChIP MCF-7 GSE41561.ESR1.MCF-7 191 bp overlap
ChIP MCF-7 GSE68355.ESR1.MCF-7 186 bp overlap
ChIP MCF-7 GSE76893.ESR1.MCF-7 173 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 159 bp overlap
ChIP MCF-7 GSE103023.ESR1.MCF-7 157 bp overlap
ChIP MCF-7_AZD2014 GSE103023.ESR1.MCF-7_AZD2014 198 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 198 bp overlap
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 106 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 103 bp overlap
ChIP MCF-7_E2+4OHT GSE119702.ESR1.MCF-7_E2+4OHT 126 bp overlap
ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 216 bp overlap
ChIP MCF-7_E2-10min-ERalpha GSE94023.ESR1.MCF-7_E2-10min-ERalpha 149 bp overlap
ChIP MCF-7_E2-1280-min-ERalpha GSE94023.ESR1.MCF-7_E2-1280-min-ERalpha 218 bp overlap
ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 166 bp overlap
ChIP MCF-7_E2-320min-ERalpha GSE94023.ESR1.MCF-7_E2-320min-ERalpha 138 bp overlap
ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 212 bp overlap
ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 154 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 178 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 189 bp overlap
ChIP MCF-7_ESR1_wildtype GSE100074.ESR1.MCF-7_ESR1_wildtype 231 bp overlap
ChIP MCF-7_G6274 GSE117941.ESR1.MCF-7_G6274 187 bp overlap
ChIP MCF-7_HC11 GSE102882.ESR1.MCF-7_HC11 180 bp overlap
ChIP MCF-7_ICI GSE125594.ESR1.MCF-7_ICI 150 bp overlap
ChIP MCF-7_IL1b_45m GSE67295.ESR1.MCF-7_IL1b_45m 146 bp overlap
ChIP MCF-7_LY2_ETOH GSE54592.ESR1.MCF-7_LY2_ETOH 129 bp overlap
ChIP MCF-7_OHT GSE119702.ESR1.MCF-7_OHT 126 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 170 bp overlap
ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 231 bp overlap
ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 206 bp overlap
ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 154 bp overlap
ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 216 bp overlap
ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 177 bp overlap
ChIP MCF-7_Veh_sc GSE117569.ESR1.MCF-7_Veh_sc 231 bp overlap
ChIP MCF-7_estradiol-Dex_75min GSE99626.ESR1.MCF-7_estradiol-Dex_75min 122 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 187 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 166 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 136 bp overlap
ChIP MCF-7_jc5855 GSE126004.ESR1.MCF-7_jc5855 161 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 154 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 136 bp overlap
ChIP MCF-7_shCtrl GSE125594.ESR1.MCF-7_shCtrl 175 bp overlap
ChIP MCF-7_shFbxo GSE119702.ESR1.MCF-7_shFbxo 138 bp overlap
ChIP MCF-7_shFbxo_E2 GSE119702.ESR1.MCF-7_shFbxo_E2 138 bp overlap
ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 190 bp overlap
ChIP MCF-7_shYAP1 GSE125594.ESR1.MCF-7_shYAP1 172 bp overlap
ESR1_Y537C 1 dataset
ChIP MCF-7_ESR1_mutant_LTED GSE100074.ESR1_Y537C.MCF-7_ESR1_mutant_LTED 211 bp overlap
ESR1_Y537N 2 datasets
ChIP MCF-7_E2_talen GSE94493.ESR1_Y537N.MCF-7_E2_talen 154 bp overlap
ChIP MCF-7_talen GSE94493.ESR1_Y537N.MCF-7_talen 176 bp overlap
ESR1_Y537S 1 dataset
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 171 bp overlap
FEZF1 1 dataset
ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 175 bp overlap
FOXA1 2 datasets
ChIP MCF-7 ERP001226.FOXA1.MCF-7 166 bp overlap
ChIP MCF-7_E2_TAM ERP000380.FOXA1.MCF-7_E2_TAM 133 bp overlap
FOXA2 1 dataset
ChIP DE DE-FOXA2-2 226 bp overlap
GATA2 2 datasets
ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 196 bp overlap
ChIP WA09 GSE105081.GATA2.WA09 142 bp overlap
GATA3 18 datasets
ChIP MCF-7 ENCFF178GBS 231 bp overlap
ChIP MCF-7 ENCFF352QVM 213 bp overlap
ChIP MCF-7 ENCFF437NQS 231 bp overlap
ChIP MCF-7 ENCSR000EWS.GATA3.MCF-7 231 bp overlap
ChIP MCF-7 GSE51274.GATA3.MCF-7 231 bp overlap
ChIP MCF-7 GSE122847.GATA3.MCF-7 223 bp overlap
ChIP MCF-7 GSE133072.GATA3.MCF-7 209 bp overlap
ChIP MCF-7 GSE128445.GATA3.MCF-7 183 bp overlap
ChIP MCF-7 ENCSR000EWV.GATA3.MCF-7 172 bp overlap
ChIP MCF-7 GSE117492.GATA3.MCF-7 166 bp overlap
ChIP MCF-7_DMSO GSE29073.GATA3.MCF-7_DMSO 127 bp overlap
ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 172 bp overlap
ChIP MCF-7_E2 GSE40129.GATA3.MCF-7_E2 136 bp overlap
ChIP MCF-7_E2 GSE29073.GATA3.MCF-7_E2 128 bp overlap
ChIP MCF-7_E2 GSE60270.GATA3.MCF-7_E2 121 bp overlap
ChIP MCF-7_E2_Dex GSE81510.GATA3.MCF-7_E2_Dex 157 bp overlap
ChIP MCF-7_ICI GSE81510.GATA3.MCF-7_ICI 143 bp overlap
ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 159 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 231 bp overlap
ChIP DE DE-GATA4-2 231 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 231 bp overlap
ChIP foregut GSE117136.GATA4.foregut 231 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 231 bp overlap
ChIP DE DE-GATA6-2 231 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 231 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 231 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 231 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 231 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 231 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 231 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 231 bp overlap
ChIP foregut GSE117136.GATA6.foregut 217 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 231 bp overlap
GRHL2 1 dataset
ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 224 bp overlap
HIC1 2 datasets
ChIP HEK293 ENCFF252CFL 231 bp overlap
ChIP HEK293 ENCSR803GYT.HIC1.HEK293 178 bp overlap
IKZF3 1 dataset
ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 152 bp overlap
KLF5 1 dataset
ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 210 bp overlap
MAX 1 dataset
ChIP MCF-7 ENCSR000BUL.MAX.MCF-7 130 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 231 bp overlap
NR3C1_mut 1 dataset
ChIP MCF-7_E2_Dex GSE81510.NR3C1_mut.MCF-7_E2_Dex 170 bp overlap
NRIP1 1 dataset
ChIP MCF-7 ERP005838.NRIP1.MCF-7 125 bp overlap
PGR 1 dataset
ChIP MCF-7_R5020 GSE68355.PGR.MCF-7_R5020 139 bp overlap
POLR2A 4 datasets
ChIP HeLa-S3 ENCFF224LWS 133 bp overlap
ChIP HeLa-S3 ENCFF224LWS 231 bp overlap
ChIP HeLa-S3 ENCFF224LWS 231 bp overlap
ChIP IMR-90 ENCFF672YWV 231 bp overlap
PRDM6 1 dataset
ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 178 bp overlap
SIN3A 1 dataset
ChIP MCF-7 ENCSR000BUM.SIN3A.MCF-7 197 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 231 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 231 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 186 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 231 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 231 bp overlap
SMARCA4 1 dataset
ChIP MCF-7 GSE140185.SMARCA4.MCF-7 231 bp overlap
SMARCB1 2 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 132 bp overlap
ChIP MCF-7_Fulvestrant GSE123284.SMARCB1.MCF-7_Fulvestrant 89 bp overlap
SMARCC1 1 dataset
ChIP MCF-7 GSE124225.SMARCC1.MCF-7 186 bp overlap
SMARCD3 2 datasets
ChIP MCF-7 GSE124225.SMARCD3.MCF-7 128 bp overlap
ChIP MCF-7_KO GSE124225.SMARCD3.MCF-7_KO 132 bp overlap
STAT3 5 datasets
ChIP MCF-7 GSE152203.STAT3.MCF-7 96 bp overlap
ChIP MCF-7_jc5834 GSE126004.STAT3.MCF-7_jc5834 160 bp overlap
ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 200 bp overlap
ChIP MCF-7_jc5840 GSE126004.STAT3.MCF-7_jc5840 198 bp overlap
ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 210 bp overlap
TCF7L2 2 datasets
ChIP HEK293 ENCFF513JQN 231 bp overlap
ChIP HEK293 ENCSR000EUY.TCF7L2.HEK293 212 bp overlap
WT1 1 dataset
ChIP HEK293 ENCSR966PJJ.WT1.HEK293 207 bp overlap
YY1 2 datasets
ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 173 bp overlap
ChIP liver ENCSR994YLZ.YY1.liver 202 bp overlap
ZBTB33 1 dataset
ChIP liver ENCFF592BJA 231 bp overlap
ZIC2 1 dataset
ChIP HEK293 ENCFF033NQQ 231 bp overlap
ZNF35 1 dataset
ChIP HEK293 GSE76494.ZNF35.HEK293 111 bp overlap
ZNF574 1 dataset
ChIP HEK293 GSE76494.ZNF574.HEK293 146 bp overlap
ZNF843 1 dataset
ChIP HEK293 ENCFF241QRH 231 bp overlap
ZSCAN16 1 dataset
ChIP HEK293 GSE76494.ZSCAN16.HEK293 231 bp overlap
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