chr6 : 166,040,358 – 166,040,865
507 bp 85 TFs 1 linked gene
This 507 bp open chromatin element is linked to PDE10A and is bound by 85 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PDE10A 379.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:166,035,358 – 166,045,865
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
85 transcription factors
Source
Cell type
ATOH7 1 dataset
Motif DE_48h DE_48h-ATOH7_MA1468.1 10 bp overlap
Atoh1 1 dataset
Motif DE_48h DE_48h-Atoh1_MA0461.3 8 bp overlap
BHLHA15 1 dataset
Motif DE_48h DE_48h-BHLHA15_MA0607.2 10 bp overlap
BHLHE22 1 dataset
Motif DE_48h DE_48h-BHLHE22_MA0818.2 10 bp overlap
BHLHE23 1 dataset
Motif DE_48h DE_48h-BHLHE23_MA0817.2 10 bp overlap
CTCF 1 dataset
Motif DE_48h DE_48h-CTCF_MA0139.2 15 bp overlap
EHF 3 datasets
Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap
Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap
Motif DE_60h DE_60h-EHF_MA0598.4 9 bp overlap
ELF1 2 datasets
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
Motif DE_60h DE_60h-ELF1_MA0473.4 9 bp overlap
ELF3 3 datasets
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
Motif DE_60h DE_60h-ELF3_MA0640.3 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 205 bp overlap
ERF::SREBF2 2 datasets
Motif DE_48h DE_48h-ERFSREBF2_MA1939.2 16 bp overlap
Motif DE_60h DE_60h-ERFSREBF2_MA1939.2 16 bp overlap
ETV5::DRGX 2 datasets
Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_60h DE_60h-ETV5DRGX_MA1944.2 12 bp overlap
ETV5::HOXA2 2 datasets
Motif DE_48h DE_48h-ETV5HOXA2_MA1948.2 12 bp overlap
Motif DE_60h DE_60h-ETV5HOXA2_MA1948.2 12 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Elf5 3 datasets
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 507 bp overlap
ChIP DE DE-FOXA2-2 456 bp overlap
FOXC2 1 dataset
Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap
FOXD2 1 dataset
Motif DE_48h DE_48h-FOXD2_MA0847.4 11 bp overlap
FOXD3 1 dataset
Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap
FOXO1-PAX3 1 dataset
ChIP RH4_Entinostat-6H GSE116344.FOXO1-PAX3.RH4_Entinostat-6H 79 bp overlap
GATA2 1 dataset
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 440 bp overlap
ChIP DE DE-GATA4-2 504 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 456 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 278 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 406 bp overlap
GATA5 1 dataset
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
GATA6 8 datasets
ChIP DE DE-GATA6-1 507 bp overlap
ChIP DE DE-GATA6-2 507 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 507 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 442 bp overlap
ChIP foregut GSE117136.GATA6.foregut 493 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 380 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 362 bp overlap
Gata3 1 dataset
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Gli2 1 dataset
Motif DE_48h DE_48h-Gli2_MA0734.4 9 bp overlap
IKZF2 3 datasets
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
IRF2 1 dataset
Motif DE_48h DE_48h-IRF2_MA0051.2 16 bp overlap
IRF7 1 dataset
Motif DE_48h DE_48h-IRF7_MA0772.2 13 bp overlap
IRF9 1 dataset
Motif DE_48h DE_48h-IRF9_MA0653.1 15 bp overlap
Irf1 1 dataset
Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap
NANOG 1 dataset
ChIP HUES-8 GSE109524.NANOG.HUES-8 331 bp overlap
NEUROG1 1 dataset
Motif DE_48h DE_48h-NEUROG1_MA0623.2 10 bp overlap
NEUROG2 1 dataset
Motif DE_48h DE_48h-NEUROG2_MA0669.1 10 bp overlap
NFATC3 1 dataset
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
NFATC4 1 dataset
Motif DE_48h DE_48h-NFATC4_MA1525.3 9 bp overlap
NR1D2 1 dataset
Motif DE_48h DE_48h-NR1D2_MA1532.2 15 bp overlap
Nfatc1 1 dataset
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 1 dataset
Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap
Nr1h3::Rxra 1 dataset
Motif DE_48h DE_48h-Nr1h3Rxra_MA0494.2 16 bp overlap
OLIG1 1 dataset
Motif DE_48h DE_48h-OLIG1_MA0826.1 10 bp overlap
OLIG2 1 dataset
Motif DE_48h DE_48h-OLIG2_MA0678.1 10 bp overlap
OLIG3 1 dataset
Motif DE_48h DE_48h-OLIG3_MA0827.1 10 bp overlap
ONECUT1 1 dataset
Motif DE_48h DE_48h-ONECUT1_MA0679.3 9 bp overlap
PAX6 1 dataset
Motif DE_48h DE_48h-PAX6_MA0069.1 14 bp overlap
PHOX2A 2 datasets
Motif DE_48h DE_48h-PHOX2A_MA0713.1 11 bp overlap
Motif DE_60h DE_60h-PHOX2A_MA0713.1 11 bp overlap
PHOX2B 2 datasets
Motif DE_48h DE_48h-PHOX2B_MA0681.3 12 bp overlap
Motif DE_60h DE_60h-PHOX2B_MA0681.3 12 bp overlap
PROP1 2 datasets
Motif DE_48h DE_48h-PROP1_MA0715.1 11 bp overlap
Motif DE_60h DE_60h-PROP1_MA0715.1 11 bp overlap
Prdm15 1 dataset
Motif DE_48h DE_48h-Prdm15_MA1616.2 11 bp overlap
Ptf1A 1 dataset
Motif DE_48h DE_48h-Ptf1A_MA1618.2 9 bp overlap
RELA 6 datasets
ChIP Detroit-562_LPS GSE91018.RELA.Detroit-562_LPS 212 bp overlap
ChIP Detroit-562_Pam2CSK4 GSE91018.RELA.Detroit-562_Pam2CSK4 263 bp overlap
ChIP Detroit-562_Poly-I GSE91018.RELA.Detroit-562_Poly-I 282 bp overlap
ChIP Detroit-562_TNFa GSE91018.RELA.Detroit-562_TNFa 276 bp overlap
ChIP Detroit-562_tri-DAP GSE91018.RELA.Detroit-562_tri-DAP 178 bp overlap
ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 384 bp overlap
RREB1 1 dataset
Motif DE_48h DE_48h-RREB1_MA0073.2 19 bp overlap
SIX1 2 datasets
Motif DE_48h DE_48h-SIX1_MA1118.2 9 bp overlap
Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap
SIX2 2 datasets
Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 401 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 283 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 283 bp overlap
SOX15 1 dataset
Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 250 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 507 bp overlap
SOX18 1 dataset
Motif DE_48h DE_48h-SOX18_MA1563.2 8 bp overlap
SOX8 1 dataset
Motif DE_48h DE_48h-SOX8_MA0868.3 7 bp overlap
SOX9 1 dataset
Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap
SPIB 3 datasets
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap
SRY 1 dataset
Motif DE_48h DE_48h-SRY_MA0084.2 7 bp overlap
Sox17 1 dataset
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Sox5 1 dataset
Motif DE_48h DE_48h-Sox5_MA0087.3 8 bp overlap
Sox6 1 dataset
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Sox7 1 dataset
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Spi1 1 dataset
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
Stat2 1 dataset
Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap
Stat5a::Stat5b 1 dataset
Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap
TAL1::TCF3 1 dataset
Motif DE_48h DE_48h-TAL1TCF3_MA0091.2 10 bp overlap
TFAP4 1 dataset
Motif DE_48h DE_48h-TFAP4_MA1570.1 10 bp overlap
TRPS1 1 dataset
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Vdr 1 dataset
Motif DE_48h DE_48h-Vdr_MA0693.4 7 bp overlap
ZBTB24 1 dataset
Motif DE_48h DE_48h-ZBTB24_MA2330.1 10 bp overlap
ZBTB26 1 dataset
Motif DE_48h DE_48h-ZBTB26_MA1579.2 8 bp overlap
ZIC5 1 dataset
Motif DE_48h DE_48h-ZIC5_MA1584.2 15 bp overlap
ZNF157 1 dataset
Motif DE_48h DE_48h-ZNF157_MA2331.1 21 bp overlap
ZNF214 2 datasets
Motif DE_48h DE_48h-ZNF214_MA1975.2 13 bp overlap
Motif DE_60h DE_60h-ZNF214_MA1975.2 13 bp overlap
ZNF418 2 datasets
Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap
Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap
ZNF740 1 dataset
Motif DE_48h DE_48h-ZNF740_MA0753.3 10 bp overlap
ZNF766 1 dataset
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
Zfp335 1 dataset
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Huangfu Lab · Publications · Resources · Contact