chr6:52,413,171–52,413,920

chr6 : 52,413,171 – 52,413,920

749 bp 46 TFs 7 linked genes

This 749 bp open chromatin element is linked to 7 target genes and is bound by 46 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PAQR8		51.4 kb	Distal	Multiome
EFHC1		51.4 kb	Distal	Multiome
MCM3		128.8 kb	Distal	Multiome+HiCAR
TRAM2		163.5 kb	Distal	Multiome+HiCAR
TMEM14A		257.5 kb	Distal	Multiome+HiCAR
CILK1		648.2 kb	Distal	Multiome+HiCAR
FBXO9		651.9 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

46 transcription factors

ARNTL 1 dataset

ChIP U2OS_DMOG GSE85096.ARNTL.U2OS_DMOG 180 bp overlap

Arid3a 2 datasets

Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap

Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap

Atoh1 3 datasets

Motif DE_48h DE_48h-Atoh1_MA1467.3 7 bp overlap

Motif DE_48h DE_48h-Atoh1_MA1467.3 7 bp overlap

Motif DE_60h DE_60h-Atoh1_MA1467.3 7 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 50 bp overlap

ESR1 2 datasets

Motif DE_48h DE_48h-ESR1_MA0112.4 15 bp overlap

Motif DE_60h DE_60h-ESR1_MA0112.4 15 bp overlap

EWSR1-FLI1 2 datasets

Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 317 bp overlap

ChIP DE DE-FOXA2-2 519 bp overlap

GATA2 1 dataset

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 192 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 159 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 510 bp overlap

ChIP DE DE-GATA4-2 565 bp overlap

GATA6 3 datasets

ChIP DE DE-GATA6-1 417 bp overlap

ChIP DE DE-GATA6-2 440 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 368 bp overlap

HAND2 3 datasets

Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap

Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap

Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap

IRF4 2 datasets

Motif DE_48h DE_48h-IRF4_MA1419.2 14 bp overlap

Motif DE_60h DE_60h-IRF4_MA1419.2 14 bp overlap

IRF6 2 datasets

Motif DE_48h DE_48h-IRF6_MA1509.1 9 bp overlap

Motif DE_60h DE_60h-IRF6_MA1509.1 9 bp overlap

IRF8 2 datasets

Motif DE_48h DE_48h-IRF8_MA0652.2 13 bp overlap

Motif DE_60h DE_60h-IRF8_MA0652.2 13 bp overlap

IRF9 2 datasets

Motif DE_48h DE_48h-IRF9_MA0653.1 15 bp overlap

Motif DE_60h DE_60h-IRF9_MA0653.1 15 bp overlap

KLF5 2 datasets

Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap

Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap

Lef1 2 datasets

Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap

Motif DE_60h DE_60h-Lef1_MA0768.3 8 bp overlap

Motif DE_48h DE_48h-MAZ_MA1522.2 8 bp overlap

Motif DE_60h DE_60h-MAZ_MA1522.2 8 bp overlap

ChIP MM1-S_JQ1_5NM GSE49224.MED1.MM1-S_JQ1_5NM 242 bp overlap

MITF 4 datasets

ChIP 501-mel GSE137522.MITF.501-mel 139 bp overlap

ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 122 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 63 bp overlap

ChIP K562 ENCFF731XJJ 131 bp overlap

Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap

NEUROD1 2 datasets

Motif DE_48h DE_48h-NEUROD1_MA1109.2 8 bp overlap

Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 3 datasets

Motif DE_48h DE_48h-NEUROG2_MA1642.2 7 bp overlap

Motif DE_48h DE_48h-NEUROG2_MA1642.2 7 bp overlap

Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap

Neurod2 2 datasets

Motif DE_48h DE_48h-Neurod2_MA0668.3 8 bp overlap

Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap

Nr2e3 2 datasets

Motif DE_48h DE_48h-Nr2e3_MA0164.2 6 bp overlap

Motif DE_60h DE_60h-Nr2e3_MA0164.2 6 bp overlap

PRDM9 2 datasets

Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap

Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap

Ptf1A 2 datasets

Motif DE_48h DE_48h-Ptf1A_MA1618.2 9 bp overlap

Motif DE_60h DE_60h-Ptf1A_MA1618.2 9 bp overlap

RBPJ 3 datasets

Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap

Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap

Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 330 bp overlap

SOX15 1 dataset

Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 242 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 731 bp overlap

Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap

Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

TFEB 2 datasets

Motif DE_48h DE_48h-TFEB_MA0692.2 8 bp overlap

Motif DE_60h DE_60h-TFEB_MA0692.2 8 bp overlap

Thap11 2 datasets

Motif DE_48h DE_48h-Thap11_MA1573.2 14 bp overlap

Motif DE_60h DE_60h-Thap11_MA1573.2 14 bp overlap

VEZF1 2 datasets

Motif DE_48h DE_48h-VEZF1_MA1578.2 6 bp overlap

Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap

ZKSCAN5 2 datasets

Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap

Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF148 2 datasets

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap

ZNF281 2 datasets

Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap

Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap

ZNF317 2 datasets

Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap

Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap

ZNF341 2 datasets

Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap

Motif DE_60h DE_60h-ZNF341_MA1655.2 8 bp overlap

ZNF343 2 datasets

Motif DE_48h DE_48h-ZNF343_MA1711.2 16 bp overlap

Motif DE_60h DE_60h-ZNF343_MA1711.2 16 bp overlap

ZNF740 2 datasets

Motif DE_48h DE_48h-ZNF740_MA0753.3 10 bp overlap

Motif DE_60h DE_60h-ZNF740_MA0753.3 10 bp overlap

ZSCAN4 1 dataset

ChIP HEK293 ENCSR211GNP.ZSCAN4.HEK293 89 bp overlap