chr4 : 176,186,135 – 176,186,515

380 bp 65 TFs 1 linked gene

This 380 bp open chromatin element is linked to SPATA4 and is bound by 65 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
SPATA4		9.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

65 transcription factors

Atf3 2 datasets

Motif DE_12h DE_12h-Atf3_MA1988.2 7 bp overlap

Motif ES_0h ES_0h-Atf3_MA1988.2 7 bp overlap

BACH1 2 datasets

Motif DE_12h DE_12h-BACH1_MA1633.2 9 bp overlap

Motif ES_0h ES_0h-BACH1_MA1633.2 9 bp overlap

BACH2 2 datasets

Motif DE_12h DE_12h-BACH2_MA1101.3 11 bp overlap

Motif ES_0h ES_0h-BACH2_MA1101.3 11 bp overlap

BATF 2 datasets

Motif DE_12h DE_12h-BATF_MA1634.2 7 bp overlap

Motif ES_0h ES_0h-BATF_MA1634.2 7 bp overlap

BATF3 2 datasets

Motif DE_12h DE_12h-BATF3_MA0835.3 7 bp overlap

Motif ES_0h ES_0h-BATF3_MA0835.3 7 bp overlap

BATF::JUN 2 datasets

Motif DE_12h DE_12h-BATFJUN_MA0462.3 7 bp overlap

Motif ES_0h ES_0h-BATFJUN_MA0462.3 7 bp overlap

BNC2 2 datasets

Motif DE_12h DE_12h-BNC2_MA1928.2 7 bp overlap

Motif ES_0h ES_0h-BNC2_MA1928.2 7 bp overlap

BRD4 1 dataset

ChIP LPS141 GSE111253.BRD4.LPS141 255 bp overlap

EGR1 1 dataset

ChIP fibroblast_DOX-CLOB-24h GSE134924.EGR1.fibroblast_DOX-CLOB-24h 100 bp overlap

Elf5 2 datasets

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

Motif ES_0h ES_0h-Elf5_MA0136.4 8 bp overlap

FOS 2 datasets

Motif DE_12h DE_12h-FOS_MA0476.2 8 bp overlap

Motif ES_0h ES_0h-FOS_MA0476.2 8 bp overlap

FOS::JUN 2 datasets

Motif DE_12h DE_12h-FOSJUN_MA0099.4 9 bp overlap

Motif ES_0h ES_0h-FOSJUN_MA0099.4 9 bp overlap

FOS::JUNB 2 datasets

Motif DE_12h DE_12h-FOSJUNB_MA1134.2 9 bp overlap

Motif ES_0h ES_0h-FOSJUNB_MA1134.2 9 bp overlap

FOS::JUND 2 datasets

Motif DE_12h DE_12h-FOSJUND_MA1141.2 9 bp overlap

Motif ES_0h ES_0h-FOSJUND_MA1141.2 9 bp overlap

FOSB::JUNB 2 datasets

Motif DE_12h DE_12h-FOSBJUNB_MA1135.2 9 bp overlap

Motif ES_0h ES_0h-FOSBJUNB_MA1135.2 9 bp overlap

FOSL1 2 datasets

Motif DE_12h DE_12h-FOSL1_MA0477.3 9 bp overlap

Motif ES_0h ES_0h-FOSL1_MA0477.3 9 bp overlap

FOSL1::JUN 2 datasets

Motif DE_12h DE_12h-FOSL1JUN_MA1128.2 9 bp overlap

Motif ES_0h ES_0h-FOSL1JUN_MA1128.2 9 bp overlap

FOSL1::JUNB 2 datasets

Motif DE_12h DE_12h-FOSL1JUNB_MA1137.2 9 bp overlap

Motif ES_0h ES_0h-FOSL1JUNB_MA1137.2 9 bp overlap

FOSL1::JUND 2 datasets

Motif DE_12h DE_12h-FOSL1JUND_MA1142.2 8 bp overlap

Motif ES_0h ES_0h-FOSL1JUND_MA1142.2 8 bp overlap

FOSL2 2 datasets

Motif DE_12h DE_12h-FOSL2_MA0478.2 10 bp overlap

Motif ES_0h ES_0h-FOSL2_MA0478.2 10 bp overlap

FOSL2::JUN 2 datasets

Motif DE_12h DE_12h-FOSL2JUN_MA1130.2 9 bp overlap

Motif ES_0h ES_0h-FOSL2JUN_MA1130.2 9 bp overlap

FOSL2::JUNB 2 datasets

Motif DE_12h DE_12h-FOSL2JUNB_MA1138.2 9 bp overlap

Motif ES_0h ES_0h-FOSL2JUNB_MA1138.2 9 bp overlap

FOSL2::JUND 2 datasets

Motif DE_12h DE_12h-FOSL2JUND_MA1144.2 9 bp overlap

Motif ES_0h ES_0h-FOSL2JUND_MA1144.2 9 bp overlap

FOXA1 1 dataset

ChIP T-47D_JC4745 GSE126004.FOXA1.T-47D_JC4745 120 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 99 bp overlap

GATA2 1 dataset

ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 130 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 52 bp overlap

HOXB4 2 datasets

Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap

Motif ES_0h ES_0h-HOXB4_MA1499.2 6 bp overlap

HOXC4 2 datasets

Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap

Motif ES_0h ES_0h-HOXC4_MA1504.2 6 bp overlap

HOXD4 2 datasets

Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap

Motif ES_0h ES_0h-HOXD4_MA1507.2 6 bp overlap

IKZF2 2 datasets

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap

JDP2 2 datasets

Motif DE_12h DE_12h-JDP2_MA0655.1 9 bp overlap

Motif ES_0h ES_0h-JDP2_MA0655.1 9 bp overlap

JUN 3 datasets

ChIP DE_D1 S40-DE-d1-JUN-exp2 332 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 289 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 347 bp overlap

JUN::JUNB 2 datasets

Motif DE_12h DE_12h-JUNJUNB_MA1132.2 8 bp overlap

Motif ES_0h ES_0h-JUNJUNB_MA1132.2 8 bp overlap

JUNB 3 datasets

ChIP CFPAC-1 GSE119930.JUNB.CFPAC-1 380 bp overlap

Motif DE_12h DE_12h-JUNB_MA0490.3 9 bp overlap

Motif ES_0h ES_0h-JUNB_MA0490.3 9 bp overlap

JUND 2 datasets

Motif DE_12h DE_12h-JUND_MA0491.3 9 bp overlap

Motif ES_0h ES_0h-JUND_MA0491.3 9 bp overlap

Jun 2 datasets

Motif DE_12h DE_12h-Jun_MA0489.3 8 bp overlap

Motif ES_0h ES_0h-Jun_MA0489.3 8 bp overlap

MAFG::NFE2L1 2 datasets

Motif DE_12h DE_12h-MAFGNFE2L1_MA0089.3 11 bp overlap

Motif ES_0h ES_0h-MAFGNFE2L1_MA0089.3 11 bp overlap

MZF1 1 dataset

ChIP HEK293 ENCSR298QUH.MZF1.HEK293 125 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 380 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 209 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 256 bp overlap

ChIP hESC GSE18292.NANOG.hESC 74 bp overlap

NFE2 2 datasets

Motif DE_12h DE_12h-NFE2_MA0841.2 10 bp overlap

Motif ES_0h ES_0h-NFE2_MA0841.2 10 bp overlap

PBX3 2 datasets

Motif DE_12h DE_12h-PBX3_MA1114.2 11 bp overlap

Motif ES_0h ES_0h-PBX3_MA1114.2 11 bp overlap

PKNOX1 2 datasets

Motif DE_12h DE_12h-PKNOX1_MA0782.3 10 bp overlap

Motif ES_0h ES_0h-PKNOX1_MA0782.3 10 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 2 datasets

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 113 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 3 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 309 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 293 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

POU6F1 2 datasets

Motif DE_12h DE_12h-POU6F1_MA1549.2 7 bp overlap

Motif ES_0h ES_0h-POU6F1_MA1549.2 7 bp overlap

POU6F2 2 datasets

Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap

Motif ES_0h ES_0h-POU6F2_MA0793.2 9 bp overlap

PRDM1 1 dataset

ChIP HEK293 ENCFF302TBP 109 bp overlap

RORB 1 dataset

Motif DE_12h DE_12h-RORB_MA1150.2 10 bp overlap

RORC 1 dataset

Motif DE_12h DE_12h-RORC_MA1151.2 10 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 285 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 206 bp overlap

TFAP2C 1 dataset

ChIP HCC1954 GSE126897.TFAP2C.HCC1954 100 bp overlap

USF1 1 dataset

ChIP WA01 ENCSR000BIU.USF1.WA01 203 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 106 bp overlap

ZNF257 1 dataset

ChIP HEK293T GSE78099.ZNF257.HEK293T 123 bp overlap

ZNF317 1 dataset

ChIP HEK293 GSE76494.ZNF317.HEK293 134 bp overlap

ZNF366 1 dataset

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 316 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 164 bp overlap

ZNF692 1 dataset

ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 108 bp overlap