chr4 : 4,142,740 – 4,143,168
428 bp 52 TFs 6 linked genes
This 428 bp open chromatin element is linked to 6 target genes and is bound by 52 transcription factors.
Linked Genes
6 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000290888 35.4 kb Distal Multiome
TMEM128 105.3 kb Distal Multiome
LYAR 147.2 kb Distal Multiome
ZBTB49 147.3 kb Distal Multiome
FAM86EP 187.5 kb Distal Multiome
NSG1 243.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:4,137,740 – 4,148,168
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
52 transcription factors
Source
Cell type
BRD4 1 dataset
ChIP hESC GSE33281.BRD4.hESC 61 bp overlap
CREB1 1 dataset
ChIP GM23338 ENCFF432ZEW 305 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF262VBH 220 bp overlap
EGR1 4 datasets
Motif DE_12h DE_12h-EGR1_MA0162.5 10 bp overlap
Motif DE_24h DE_24h-EGR1_MA0162.5 10 bp overlap
Motif DE_36h DE_36h-EGR1_MA0162.5 10 bp overlap
Motif DE_72h DE_72h-EGR1_MA0162.5 10 bp overlap
EGR3 4 datasets
Motif DE_12h DE_12h-EGR3_MA0732.2 11 bp overlap
Motif DE_24h DE_24h-EGR3_MA0732.2 11 bp overlap
Motif DE_36h DE_36h-EGR3_MA0732.2 11 bp overlap
Motif DE_72h DE_72h-EGR3_MA0732.2 11 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_24h DE_24h-EWSR1-FLI1_MA0149.1 18 bp overlap
GLI3 3 datasets
Motif DE_12h DE_12h-GLI3_MA1491.3 15 bp overlap
Motif DE_24h DE_24h-GLI3_MA1491.3 15 bp overlap
Motif DE_36h DE_36h-GLI3_MA1491.3 15 bp overlap
KDM4A 1 dataset
ChIP H1 ENCFF078LED 428 bp overlap
KLF1 11 datasets
Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap
Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap
Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap
Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap
Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap
Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap
Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap
Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap
Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap
Motif DE_72h DE_72h-KLF1_MA0493.3 8 bp overlap
Motif DE_72h DE_72h-KLF1_MA0493.3 8 bp overlap
KLF10 11 datasets
Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap
Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap
Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap
Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap
Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap
Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap
Motif DE_36h DE_36h-KLF10_MA1511.2 9 bp overlap
Motif DE_36h DE_36h-KLF10_MA1511.2 9 bp overlap
Motif DE_36h DE_36h-KLF10_MA1511.2 9 bp overlap
Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap
Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap
KLF11 8 datasets
Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap
Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap
Motif DE_24h DE_24h-KLF11_MA1512.2 10 bp overlap
Motif DE_24h DE_24h-KLF11_MA1512.2 10 bp overlap
Motif DE_36h DE_36h-KLF11_MA1512.2 10 bp overlap
Motif DE_36h DE_36h-KLF11_MA1512.2 10 bp overlap
Motif DE_72h DE_72h-KLF11_MA1512.2 10 bp overlap
Motif DE_72h DE_72h-KLF11_MA1512.2 10 bp overlap
KLF12 8 datasets
Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap
Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap
Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap
Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap
Motif DE_36h DE_36h-KLF12_MA0742.2 9 bp overlap
Motif DE_36h DE_36h-KLF12_MA0742.2 9 bp overlap
Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap
Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap
KLF14 8 datasets
Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap
Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap
Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap
Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap
Motif DE_36h DE_36h-KLF14_MA0740.2 9 bp overlap
Motif DE_36h DE_36h-KLF14_MA0740.2 9 bp overlap
Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap
Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap
KLF15 8 datasets
Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap
Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap
Motif DE_24h DE_24h-KLF15_MA1513.2 8 bp overlap
Motif DE_24h DE_24h-KLF15_MA1513.2 8 bp overlap
Motif DE_36h DE_36h-KLF15_MA1513.2 8 bp overlap
Motif DE_36h DE_36h-KLF15_MA1513.2 8 bp overlap
Motif DE_72h DE_72h-KLF15_MA1513.2 8 bp overlap
Motif DE_72h DE_72h-KLF15_MA1513.2 8 bp overlap
KLF16 8 datasets
Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap
Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap
Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap
Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap
Motif DE_36h DE_36h-KLF16_MA0741.1 11 bp overlap
Motif DE_36h DE_36h-KLF16_MA0741.1 11 bp overlap
Motif DE_72h DE_72h-KLF16_MA0741.1 11 bp overlap
Motif DE_72h DE_72h-KLF16_MA0741.1 11 bp overlap
KLF2 11 datasets
Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap
Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap
Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap
Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap
Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap
Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap
Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap
Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap
Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap
Motif DE_72h DE_72h-KLF2_MA1515.2 8 bp overlap
Motif DE_72h DE_72h-KLF2_MA1515.2 8 bp overlap
KLF3 4 datasets
Motif DE_12h DE_12h-KLF3_MA1516.2 10 bp overlap
Motif DE_24h DE_24h-KLF3_MA1516.2 10 bp overlap
Motif DE_36h DE_36h-KLF3_MA1516.2 10 bp overlap
Motif DE_72h DE_72h-KLF3_MA1516.2 10 bp overlap
KLF4 11 datasets
Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap
Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap
Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap
Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap
Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap
Motif DE_72h DE_72h-KLF4_MA0039.5 8 bp overlap
Motif DE_72h DE_72h-KLF4_MA0039.5 8 bp overlap
KLF5 11 datasets
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap
Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap
Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap
Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap
KLF6 3 datasets
Motif DE_12h DE_12h-KLF6_MA1517.2 9 bp overlap
Motif DE_24h DE_24h-KLF6_MA1517.2 9 bp overlap
Motif DE_36h DE_36h-KLF6_MA1517.2 9 bp overlap
KLF7 8 datasets
Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap
Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap
Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap
Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap
Motif DE_36h DE_36h-KLF7_MA1959.2 8 bp overlap
Motif DE_36h DE_36h-KLF7_MA1959.2 8 bp overlap
Motif DE_72h DE_72h-KLF7_MA1959.2 8 bp overlap
Motif DE_72h DE_72h-KLF7_MA1959.2 8 bp overlap
KLF9 7 datasets
Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap
Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap
Motif DE_24h DE_24h-KLF9_MA1107.3 11 bp overlap
Motif DE_24h DE_24h-KLF9_MA1107.3 11 bp overlap
Motif DE_36h DE_36h-KLF9_MA1107.3 11 bp overlap
Motif DE_36h DE_36h-KLF9_MA1107.3 11 bp overlap
Motif DE_72h DE_72h-KLF9_MA1107.3 11 bp overlap
NR2C1 3 datasets
Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap
Motif DE_24h DE_24h-NR2C1_MA1535.2 6 bp overlap
Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap
NR2C2 3 datasets
Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap
Motif DE_24h DE_24h-NR2C2_MA1536.2 6 bp overlap
Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap
Nr1H2 3 datasets
Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_24h DE_24h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 3 datasets
Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_24h DE_24h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 3 datasets
Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_24h DE_24h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap
PATZ1 8 datasets
Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap
Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
Motif DE_36h DE_36h-PATZ1_MA1961.2 11 bp overlap
Motif DE_36h DE_36h-PATZ1_MA1961.2 11 bp overlap
Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap
Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap
POLR2A 1 dataset
ChIP GM23338 ENCFF450WCS 428 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 354 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 410 bp overlap
PRDM9 1 dataset
Motif DE_24h DE_24h-PRDM9_MA1723.2 20 bp overlap
RARB 3 datasets
Motif DE_12h DE_12h-RARB_MA1552.2 13 bp overlap
Motif DE_24h DE_24h-RARB_MA1552.2 13 bp overlap
Motif DE_36h DE_36h-RARB_MA1552.2 13 bp overlap
Rarg 3 datasets
Motif DE_12h DE_12h-Rarg_MA0860.1 17 bp overlap
Motif DE_24h DE_24h-Rarg_MA0860.1 17 bp overlap
Motif DE_36h DE_36h-Rarg_MA0860.1 17 bp overlap
SMARCC1 1 dataset
ChIP ESC S25-ESC-d0-BAF155-exp1 387 bp overlap
SP1 4 datasets
Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap
Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap
Motif DE_36h DE_36h-SP1_MA0079.5 9 bp overlap
Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap
SP2 8 datasets
Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap
Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap
Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap
Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap
Motif DE_36h DE_36h-SP2_MA0516.3 9 bp overlap
Motif DE_36h DE_36h-SP2_MA0516.3 9 bp overlap
Motif DE_72h DE_72h-SP2_MA0516.3 9 bp overlap
Motif DE_72h DE_72h-SP2_MA0516.3 9 bp overlap
SP3 8 datasets
Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap
Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap
Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap
Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap
Motif DE_36h DE_36h-SP3_MA0746.3 11 bp overlap
Motif DE_36h DE_36h-SP3_MA0746.3 11 bp overlap
Motif DE_72h DE_72h-SP3_MA0746.3 11 bp overlap
Motif DE_72h DE_72h-SP3_MA0746.3 11 bp overlap
SP4 8 datasets
Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap
Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap
Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap
Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap
Motif DE_36h DE_36h-SP4_MA0685.2 9 bp overlap
Motif DE_36h DE_36h-SP4_MA0685.2 9 bp overlap
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
SP5 3 datasets
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
SP8 4 datasets
Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap
Motif DE_24h DE_24h-SP8_MA0747.2 11 bp overlap
Motif DE_36h DE_36h-SP8_MA0747.2 11 bp overlap
Motif DE_72h DE_72h-SP8_MA0747.2 11 bp overlap
SP9 8 datasets
Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap
Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap
Motif DE_24h DE_24h-SP9_MA1564.2 10 bp overlap
Motif DE_24h DE_24h-SP9_MA1564.2 10 bp overlap
Motif DE_36h DE_36h-SP9_MA1564.2 10 bp overlap
Motif DE_36h DE_36h-SP9_MA1564.2 10 bp overlap
Motif DE_72h DE_72h-SP9_MA1564.2 10 bp overlap
Motif DE_72h DE_72h-SP9_MA1564.2 10 bp overlap
Wt1 4 datasets
Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap
Motif DE_24h DE_24h-Wt1_MA1627.2 10 bp overlap
Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap
Motif DE_72h DE_72h-Wt1_MA1627.2 10 bp overlap
ZBED4 4 datasets
Motif DE_12h DE_12h-ZBED4_MA2328.1 10 bp overlap
Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap
Motif DE_36h DE_36h-ZBED4_MA2328.1 10 bp overlap
Motif DE_72h DE_72h-ZBED4_MA2328.1 10 bp overlap
ZIC1 3 datasets
Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap
Motif DE_24h DE_24h-ZIC1_MA0696.1 14 bp overlap
Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap
ZIC5 3 datasets
Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap
Motif DE_24h DE_24h-ZIC5_MA1584.2 15 bp overlap
Motif DE_36h DE_36h-ZIC5_MA1584.2 15 bp overlap
ZNF148 8 datasets
Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap
Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap
Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap
Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap
Motif DE_36h DE_36h-ZNF148_MA1653.2 10 bp overlap
Motif DE_36h DE_36h-ZNF148_MA1653.2 10 bp overlap
Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap
Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap
ZNF281 4 datasets
Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap
Motif DE_24h DE_24h-ZNF281_MA1630.3 10 bp overlap
Motif DE_36h DE_36h-ZNF281_MA1630.3 10 bp overlap
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF684 3 datasets
Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap
Motif DE_24h DE_24h-ZNF684_MA1600.2 14 bp overlap
Motif DE_36h DE_36h-ZNF684_MA1600.2 14 bp overlap
ZNF740 4 datasets
Motif DE_12h DE_12h-ZNF740_MA0753.3 10 bp overlap
Motif DE_24h DE_24h-ZNF740_MA0753.3 10 bp overlap
Motif DE_36h DE_36h-ZNF740_MA0753.3 10 bp overlap
Motif DE_72h DE_72h-ZNF740_MA0753.3 10 bp overlap
ZNF75D 3 datasets
Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_24h DE_24h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_36h DE_36h-ZNF75D_MA1601.2 12 bp overlap
Zfx 6 datasets
Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap
Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap
Motif DE_24h DE_24h-Zfx_MA0146.3 10 bp overlap
Motif DE_24h DE_24h-Zfx_MA0146.3 10 bp overlap
Motif DE_36h DE_36h-Zfx_MA0146.3 10 bp overlap
Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap
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