chr3 : 155,327,486 – 155,328,631
1,145 bp 59 TFs 1 linked gene
This 1.1 kb open chromatin element is linked to MME and is bound by 59 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MME 248.3 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:155,322,486 – 155,333,631
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
59 transcription factors
Source
Cell type
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 329 bp overlap
ChIP K562 ENCFF938UXQ 193 bp overlap
BRD3 1 dataset
ChIP H-1_DE GSE126661.BRD3.H-1_DE 195 bp overlap
CBFA2T2 1 dataset
ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 262 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 304 bp overlap
ChIP K562 ENCFF673OEZ 209 bp overlap
CCAR2 2 datasets
ChIP Hep-G2 ENCSR247XFV.CCAR2.Hep-G2 173 bp overlap
ChIP Hep-G2 GSE120104.CCAR2.Hep-G2 173 bp overlap
CDX2 1 dataset
ChIP LS180_125 GSE31939.CDX2.LS180_125 121 bp overlap
CTCF 1 dataset
ChIP endodermal cell ENCFF471YCZ 461 bp overlap
Crx 2 datasets
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
DPF2 1 dataset
ChIP K-562 ENCSR219BXP.DPF2.K-562 276 bp overlap
EOMES 2 datasets
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 132 bp overlap
FIGLA 1 dataset
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOXA2 3 datasets
ChIP DE DE-FOXA2-1 471 bp overlap
ChIP DE DE-FOXA2-1 440 bp overlap
ChIP DE DE-FOXA2-2 772 bp overlap
GATA1 2 datasets
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 170 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 232 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 985 bp overlap
ChIP DE DE-GATA4-2 1103 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 455 bp overlap
ChIP DE DE-GATA6-1 584 bp overlap
ChIP DE DE-GATA6-2 1063 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 1145 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 1055 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 1077 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 993 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 1119 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 1031 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 431 bp overlap
GSC 2 datasets
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
GSC2 2 datasets
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
HDAC2 2 datasets
ChIP K-562 ENCSR893WSB.HDAC2.K-562 255 bp overlap
ChIP K-562 ENCSR893WSB.HDAC2.K-562 250 bp overlap
HMBOX1 2 datasets
Motif DE_48h DE_48h-HMBOX1_MA0895.2 7 bp overlap
Motif DE_60h DE_60h-HMBOX1_MA0895.2 7 bp overlap
Hand1::Tcf3 2 datasets
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
JUN 1 dataset
ChIP DE_D1 S13-DE-d1-JUN-exp1 457 bp overlap
LDB1 1 dataset
ChIP K-562 GSE142227.LDB1.K-562 353 bp overlap
LIN54 2 datasets
Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap
Motif DE_60h DE_60h-LIN54_MA0619.2 7 bp overlap
NCOR1 1 dataset
ChIP K-562 ENCSR798ILC.NCOR1.K-562 254 bp overlap
ONECUT2 1 dataset
ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 298 bp overlap
OTX1 2 datasets
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
PHOX2B 2 datasets
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 407 bp overlap
ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 202 bp overlap
PITX1 2 datasets
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
PITX2 2 datasets
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
PITX3 2 datasets
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
PKNOX1 2 datasets
Motif DE_48h DE_48h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_60h DE_60h-PKNOX1_MA0782.3 10 bp overlap
Ptf1A 1 dataset
Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap
RBPJ 1 dataset
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
RHOXF1 2 datasets
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
SMAD2 4 datasets
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 242 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 182 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 1122 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 1145 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 1145 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 1101 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 1085 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 1145 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 1145 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 1090 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 267 bp overlap
SMAD4 2 datasets
ChIP endoderm GSE29422.SMAD4.endoderm 373 bp overlap
ChIP endoderm GSE29422.SMAD4.endoderm 152 bp overlap
SMARCA4 3 datasets
ChIP K-562 ENCSR643VTW.SMARCA4.K-562 205 bp overlap
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 270 bp overlap
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 359 bp overlap
SMARCC1 2 datasets
ChIP DE_D1 S15-DE-d1-BAF155-exp1 252 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 355 bp overlap
SMARCE1 1 dataset
ChIP K-562 ENCSR157TCS.SMARCE1.K-562 241 bp overlap
SOX13 1 dataset
Motif DE_60h DE_60h-SOX13_MA1120.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 305 bp overlap
SOX17_M 2 datasets
ChIP DE_D2 DED2-SOX17-M_Batch_II 286 bp overlap
ChIP DE_D2 DED2-SOX17-M_Batch_II 299 bp overlap
SOX2 1 dataset
Motif DE_60h DE_60h-SOX2_MA0143.5 7 bp overlap
SP8 1 dataset
Motif DE_60h DE_60h-SP8_MA0747.2 11 bp overlap
Sox3 1 dataset
Motif DE_60h DE_60h-Sox3_MA0514.3 7 bp overlap
TAL1 8 datasets
ChIP K-562 ENCSR106FRG.TAL1.K-562 286 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 202 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 190 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 218 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 226 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 283 bp overlap
ChIP K562 ENCFF620GMX 119 bp overlap
ChIP K562 ENCFF661CCK 265 bp overlap
TBR1 1 dataset
Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap
TBX18 1 dataset
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
TBX3 1 dataset
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
TEAD4 2 datasets
ChIP BE2C GSE84389.TEAD4.BE2C 178 bp overlap
ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 178 bp overlap
Tbx6 1 dataset
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
ZBTB2 1 dataset
ChIP K-562 ENCSR230PTV.ZBTB2.K-562 232 bp overlap
ZBTB7A 2 datasets
ChIP K-562 GSE103445.ZBTB7A.K-562 257 bp overlap
ChIP K-562 ENCSR000BME.ZBTB7A.K-562 93 bp overlap
ZEB1 1 dataset
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZNF558 2 datasets
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
Motif DE_60h DE_60h-ZNF558_MA2335.1 29 bp overlap
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