chr3 : 89,371,250 – 89,371,812
562 bp 57 TFs 1 linked gene
This 562 bp open chromatin element is linked to EPHA3 and is bound by 57 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
EPHA3 263.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:89,366,250 – 89,376,812
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
57 transcription factors
Source
Cell type
AR 2 datasets
ChIP LNCaP_ETOH GSE69043.AR.LNCaP_ETOH 134 bp overlap
ChIP LNCaP_SHGATA2_R1881 GSE69043.AR.LNCaP_SHGATA2_R1881 148 bp overlap
CTBP1 1 dataset
ChIP HEK293T ENCSR237TFX.CTBP1.HEK293T 224 bp overlap
DMRT3 3 datasets
Motif DE_48h DE_48h-DMRT3_MA0610.2 7 bp overlap
Motif DE_60h DE_60h-DMRT3_MA0610.2 7 bp overlap
Motif DE_72h DE_72h-DMRT3_MA0610.2 7 bp overlap
DMRTC2 3 datasets
Motif DE_48h DE_48h-DMRTC2_MA1479.2 11 bp overlap
Motif DE_60h DE_60h-DMRTC2_MA1479.2 11 bp overlap
Motif DE_72h DE_72h-DMRTC2_MA1479.2 11 bp overlap
Dmrt1 3 datasets
Motif DE_48h DE_48h-Dmrt1_MA1603.2 9 bp overlap
Motif DE_60h DE_60h-Dmrt1_MA1603.2 9 bp overlap
Motif DE_72h DE_72h-Dmrt1_MA1603.2 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 220 bp overlap
ERG 1 dataset
ChIP aortic-endothelial-cell_D13 GSE139377.ERG.aortic-endothelial-cell_D13 250 bp overlap
FOXA1 1 dataset
ChIP LNCaP_M253K GSE133386.FOXA1.LNCaP_M253K 198 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 434 bp overlap
ChIP DE DE-FOXA2-1 440 bp overlap
ChIP DE DE-FOXA2-2 491 bp overlap
FOXC1 3 datasets
Motif DE_48h DE_48h-FOXC1_MA0032.2 11 bp overlap
Motif DE_60h DE_60h-FOXC1_MA0032.2 11 bp overlap
Motif DE_72h DE_72h-FOXC1_MA0032.2 11 bp overlap
FOXC2 3 datasets
Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap
Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap
Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap
FOXD3 3 datasets
Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap
Motif DE_60h DE_60h-FOXD3_MA0041.3 14 bp overlap
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
FOXH1 1 dataset
Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap
GATA1 1 dataset
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 203 bp overlap
GATA1::TAL1 3 datasets
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 10 datasets
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
ChIP ESF GSE108408.GATA2.ESF 369 bp overlap
ChIP LNCaP GSE38391.GATA2.LNCaP 200 bp overlap
ChIP LNCaP GSE52725.GATA2.LNCaP 200 bp overlap
ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 293 bp overlap
ChIP LNCaP_FBS GSE69043.GATA2.LNCaP_FBS 216 bp overlap
ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 279 bp overlap
ChIP primary-endometrial-stromal-cell_Veh_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P2 298 bp overlap
GATA3 13 datasets
ChIP A1A3_Brg1KD_Dex GSE112491.GATA3.A1A3_Brg1KD_Dex 481 bp overlap
ChIP A1A3_Brg1KD_EtOH GSE112491.GATA3.A1A3_Brg1KD_EtOH 177 bp overlap
ChIP Jurkat GSE120063.GATA3.Jurkat 264 bp overlap
ChIP Jurkat GSE76181.GATA3.Jurkat 271 bp overlap
ChIP MCF-7 ENCFF352QVM 121 bp overlap
ChIP MCF-7 GSE122847.GATA3.MCF-7 375 bp overlap
ChIP MCF-7 GSE133072.GATA3.MCF-7 328 bp overlap
ChIP MCF-7 GSE51274.GATA3.MCF-7 216 bp overlap
ChIP MCF-7_E2 GSE40129.GATA3.MCF-7_E2 186 bp overlap
ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 346 bp overlap
ChIP T-47D_sc GSE122847.GATA3.T-47D_sc 319 bp overlap
ChIP T47D-A1-2_Dex GSE112491.GATA3.T47D-A1-2_Dex 452 bp overlap
ChIP T47D-A1-2_EtOH GSE112491.GATA3.T47D-A1-2_EtOH 434 bp overlap
GATA3_Nter 1 dataset
ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 169 bp overlap
GATA4 16 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 203 bp overlap
ChIP DE DE-GATA4-1 484 bp overlap
ChIP DE DE-GATA4-2 562 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP G296S GSE85628.GATA4.G296S 220 bp overlap
ChIP G296S_2 GSE85628.GATA4.G296S_2 220 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 197 bp overlap
ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 406 bp overlap
ChIP foregut GSE117136.GATA4.foregut 447 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 325 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 292 bp overlap
GATA5 3 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 15 datasets
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 122 bp overlap
ChIP DE DE-GATA6-1 486 bp overlap
ChIP DE DE-GATA6-2 507 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 533 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 562 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 491 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 461 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 562 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 556 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 487 bp overlap
ChIP foregut GSE117136.GATA6.foregut 358 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 276 bp overlap
Gata3 3 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Gli1 3 datasets
Motif DE_48h DE_48h-Gli1_MA1990.2 10 bp overlap
Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap
Motif DE_72h DE_72h-Gli1_MA1990.2 10 bp overlap
Gli2 3 datasets
Motif DE_48h DE_48h-Gli2_MA0734.4 9 bp overlap
Motif DE_60h DE_60h-Gli2_MA0734.4 9 bp overlap
Motif DE_72h DE_72h-Gli2_MA0734.4 9 bp overlap
HIC2 1 dataset
Motif DE_60h DE_60h-HIC2_MA0738.2 6 bp overlap
HMBOX1 3 datasets
Motif DE_48h DE_48h-HMBOX1_MA0895.2 7 bp overlap
Motif DE_60h DE_60h-HMBOX1_MA0895.2 7 bp overlap
Motif DE_72h DE_72h-HMBOX1_MA0895.2 7 bp overlap
HSF1 1 dataset
ChIP breast_tumor GSE38901.HSF1.breast_tumor 141 bp overlap
Hnf1A 3 datasets
Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap
Hoxa13 3 datasets
Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_60h DE_60h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_72h DE_72h-Hoxa13_MA0650.4 8 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 268 bp overlap
MAFF 3 datasets
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap
Motif DE_72h DE_72h-MAFF_MA0495.4 11 bp overlap
MEIS1 3 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MYB 1 dataset
Motif DE_60h DE_60h-MYB_MA0100.4 6 bp overlap
Mecom 9 datasets
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NR3C1 1 dataset
ChIP T47D-A1-2_Dex GSE112491.NR3C1.T47D-A1-2_Dex 146 bp overlap
NR6A1 1 dataset
Motif DE_60h DE_60h-NR6A1_MA1541.2 14 bp overlap
RARA 1 dataset
Motif DE_60h DE_60h-RARA_MA0730.1 17 bp overlap
Rarb 1 dataset
Motif DE_60h DE_60h-Rarb_MA0858.1 17 bp overlap
SIX1 2 datasets
Motif DE_48h DE_48h-SIX1_MA1118.2 9 bp overlap
Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 562 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 550 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 441 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 518 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 552 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 437 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 288 bp overlap
SOX15 3 datasets
Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap
Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap
Motif DE_72h DE_72h-SOX15_MA1152.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 290 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 400 bp overlap
SPDEF 1 dataset
ChIP MCF-7 ENCSR042GSX.SPDEF.MCF-7 167 bp overlap
SRF 5 datasets
Motif DE_48h DE_48h-SRF_MA0083.3 16 bp overlap
Motif DE_60h DE_60h-SRF_MA0083.3 16 bp overlap
Motif DE_72h DE_72h-SRF_MA0083.3 16 bp overlap
ChIP MCF-7 ENCFF508RYE 397 bp overlap
ChIP MCF-7 ENCSR000BVA.SRF.MCF-7 195 bp overlap
TCF7L1 3 datasets
Motif DE_48h DE_48h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 3 datasets
Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
TRPS1 4 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ChIP MCF-7 GSE133072.TRPS1.MCF-7 347 bp overlap
ZBTB18 1 dataset
Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap
ZFP42 3 datasets
Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap
Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap
Motif DE_72h DE_72h-ZFP42_MA1651.2 13 bp overlap
ZNF143 3 datasets
Motif DE_48h DE_48h-ZNF143_MA0088.2 16 bp overlap
Motif DE_60h DE_60h-ZNF143_MA0088.2 16 bp overlap
Motif DE_72h DE_72h-ZNF143_MA0088.2 16 bp overlap
ZNF157 1 dataset
Motif DE_60h DE_60h-ZNF157_MA2331.1 21 bp overlap
ZNF558 3 datasets
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
Motif DE_60h DE_60h-ZNF558_MA2335.1 29 bp overlap
Motif DE_72h DE_72h-ZNF558_MA2335.1 29 bp overlap
ZNF766 3 datasets
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap
Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap
ZNF85 3 datasets
Motif DE_48h DE_48h-ZNF85_MA1720.2 12 bp overlap
Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap
Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap
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