chr3 : 21,224,509 – 21,225,193

684 bp 75 TFs 1 linked gene

This 684 bp open chromatin element is linked to ENSG00000282987 and is bound by 75 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000282987		1.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

75 transcription factors

Atoh1 1 dataset

Motif DE_36h DE_36h-Atoh1_MA0461.3 8 bp overlap

BARX1 1 dataset

Motif DE_36h DE_36h-BARX1_MA0875.2 6 bp overlap

BHLHE22 1 dataset

Motif DE_36h DE_36h-BHLHE22_MA0818.2 10 bp overlap

BHLHE23 1 dataset

Motif DE_36h DE_36h-BHLHE23_MA0817.2 10 bp overlap

BSX 1 dataset

Motif DE_36h DE_36h-BSX_MA0876.2 6 bp overlap

DLX1 1 dataset

Motif DE_36h DE_36h-DLX1_MA0879.3 6 bp overlap

DLX6 1 dataset

Motif DE_36h DE_36h-DLX6_MA0882.2 6 bp overlap

Dlx2 1 dataset

Motif DE_36h DE_36h-Dlx2_MA0885.3 8 bp overlap

Dlx3 1 dataset

Motif DE_36h DE_36h-Dlx3_MA0880.2 6 bp overlap

Dlx4 1 dataset

Motif DE_36h DE_36h-Dlx4_MA0881.2 6 bp overlap

Dlx5 1 dataset

Motif DE_36h DE_36h-Dlx5_MA1476.3 8 bp overlap

EN2 1 dataset

Motif DE_36h DE_36h-EN2_MA0642.3 7 bp overlap

EOMES 2 datasets

Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 225 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 269 bp overlap

GATA2 1 dataset

Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 337 bp overlap

ChIP DE DE-GATA4-2 380 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

GATA5 1 dataset

Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 396 bp overlap

ChIP DE DE-GATA6-2 428 bp overlap

Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 684 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 684 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 684 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 447 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 684 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 330 bp overlap

GBX1 1 dataset

Motif DE_36h DE_36h-GBX1_MA0889.2 7 bp overlap

GBX2 1 dataset

Motif DE_36h DE_36h-GBX2_MA0890.2 6 bp overlap

Gata3 1 dataset

Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap

HESX1 1 dataset

Motif DE_36h DE_36h-HESX1_MA0894.2 6 bp overlap

HOXA7 1 dataset

Motif DE_36h DE_36h-HOXA7_MA1498.3 6 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 306 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 261 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 401 bp overlap

LBX1 1 dataset

Motif DE_36h DE_36h-LBX1_MA0618.2 7 bp overlap

LBX2 1 dataset

Motif DE_36h DE_36h-LBX2_MA0699.2 6 bp overlap

LHX2 1 dataset

Motif DE_36h DE_36h-LHX2_MA0700.3 6 bp overlap

LHX9 1 dataset

Motif DE_36h DE_36h-LHX9_MA0701.3 7 bp overlap

MEIS1 2 datasets

Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap

MGA 1 dataset

Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap

MSX1 1 dataset

Motif DE_36h DE_36h-MSX1_MA0666.3 6 bp overlap

MSX2 1 dataset

Motif DE_36h DE_36h-MSX2_MA0708.3 6 bp overlap

Msx3 1 dataset

Motif DE_36h DE_36h-Msx3_MA0709.2 6 bp overlap

Nobox 1 dataset

Motif DE_36h DE_36h-Nobox_MA0125.2 6 bp overlap

OLIG1 1 dataset

Motif DE_36h DE_36h-OLIG1_MA0826.1 10 bp overlap

OSR1 2 datasets

Motif DE_36h DE_36h-OSR1_MA1542.2 8 bp overlap

Motif DE_48h DE_48h-OSR1_MA1542.2 8 bp overlap

OSR2 2 datasets

Motif DE_36h DE_36h-OSR2_MA1646.2 8 bp overlap

Motif DE_48h DE_48h-OSR2_MA1646.2 8 bp overlap

PKNOX2 1 dataset

Motif DE_36h DE_36h-PKNOX2_MA0783.1 12 bp overlap

POU5F1 1 dataset

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 224 bp overlap

PRRX2 1 dataset

Motif DE_36h DE_36h-PRRX2_MA0075.4 7 bp overlap

RAD21 1 dataset

ChIP SK-N-SH GSE76815.RAD21.SK-N-SH 83 bp overlap

RARA 1 dataset

Motif DE_36h DE_36h-RARA_MA0729.1 18 bp overlap

RAX 1 dataset

Motif DE_36h DE_36h-RAX_MA0718.2 6 bp overlap

Rarb 1 dataset

Motif DE_36h DE_36h-Rarb_MA0857.1 16 bp overlap

Rarg 1 dataset

Motif DE_36h DE_36h-Rarg_MA0859.2 15 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 275 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 684 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 684 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 684 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 684 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 539 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 318 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 313 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 406 bp overlap

ChIP DE_D1 S15-DE-d1-BAF155-exp1 684 bp overlap

SOX10 1 dataset

Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 247 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 572 bp overlap

SOX2 1 dataset

ChIP HNSC GSE69479.SOX2.HNSC 210 bp overlap

SOX4 1 dataset

Motif DE_36h DE_36h-SOX4_MA0867.3 8 bp overlap

Sox11 1 dataset

Motif DE_36h DE_36h-Sox11_MA0869.3 8 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 228 bp overlap

TBR1 1 dataset

Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_36h DE_36h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap

TCF7L2 1 dataset

Motif DE_36h DE_36h-TCF7L2_MA0523.2 9 bp overlap

TGIF1 1 dataset

Motif DE_36h DE_36h-TGIF1_MA0796.1 12 bp overlap

TGIF2 1 dataset

Motif DE_36h DE_36h-TGIF2_MA0797.1 12 bp overlap

TGIF2LX 1 dataset

Motif DE_36h DE_36h-TGIF2LX_MA1571.1 12 bp overlap

TGIF2LY 1 dataset

Motif DE_36h DE_36h-TGIF2LY_MA1572.1 12 bp overlap

TRPS1 1 dataset

Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap

Tbx6 1 dataset

Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap

VENTX 1 dataset

Motif DE_36h DE_36h-VENTX_MA0724.1 9 bp overlap

ZKSCAN1 1 dataset

Motif DE_36h DE_36h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF675 1 dataset

Motif DE_36h DE_36h-ZNF675_MA1714.2 19 bp overlap