chr2 : 205,091,385 – 205,092,333
948 bp 64 TFs 1 linked gene
This 948 bp open chromatin element is linked to NRP2 and is bound by 64 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
NRP2 590.9 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:205,086,385 – 205,097,333
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
64 transcription factors
Source
Cell type
BCL6B 3 datasets
Motif DE_36h DE_36h-BCL6B_MA0731.1 17 bp overlap
Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap
Motif DE_60h DE_60h-BCL6B_MA0731.1 17 bp overlap
Bcl11B 3 datasets
Motif DE_36h DE_36h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_48h DE_48h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_60h DE_60h-Bcl11B_MA1989.2 9 bp overlap
CHD7 1 dataset
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 132 bp overlap
Crx 4 datasets
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
DPRX 4 datasets
Motif DE_36h DE_36h-DPRX_MA1480.2 9 bp overlap
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap
EOMES 2 datasets
ChIP hESC GSE26097.EOMES.hESC 444 bp overlap
ChIP hESC GSE26097.EOMES.hESC 253 bp overlap
ERG 2 datasets
ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 122 bp overlap
ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 127 bp overlap
ESR1 1 dataset
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 94 bp overlap
FLI1 3 datasets
ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 236 bp overlap
ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 225 bp overlap
ChIP A-673_D17 GSE129155.FLI1.A-673_D17 265 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 212 bp overlap
ChIP DE DE-FOXA2-1 469 bp overlap
ChIP DE DE-FOXA2-2 419 bp overlap
FOXE1 3 datasets
Motif DE_36h DE_36h-FOXE1_MA1487.3 12 bp overlap
Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap
Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap
GATA2 4 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
GATA4 8 datasets
ChIP DE DE-GATA4-1 948 bp overlap
ChIP DE DE-GATA4-2 948 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 399 bp overlap
ChIP foregut GSE117136.GATA4.foregut 270 bp overlap
GATA5 4 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 17 datasets
ChIP DE DE-GATA6-1 550 bp overlap
ChIP DE DE-GATA6-1 226 bp overlap
ChIP DE DE-GATA6-2 948 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 948 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 515 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 220 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 948 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 948 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 948 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 948 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 948 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 408 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 420 bp overlap
GSC 4 datasets
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 4 datasets
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gata3 4 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HSF1 1 dataset
Motif DE_48h DE_48h-HSF1_MA0486.2 13 bp overlap
HSF2 1 dataset
Motif DE_48h DE_48h-HSF2_MA0770.1 13 bp overlap
JUN 2 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 422 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 277 bp overlap
KLF17 3 datasets
Motif DE_36h DE_36h-KLF17_MA1514.2 14 bp overlap
Motif DE_48h DE_48h-KLF17_MA1514.2 14 bp overlap
Motif DE_72h DE_72h-KLF17_MA1514.2 14 bp overlap
LMO2 1 dataset
ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 131 bp overlap
Lhx3 4 datasets
Motif DE_36h DE_36h-Lhx3_MA0135.2 12 bp overlap
Motif DE_48h DE_48h-Lhx3_MA0135.2 12 bp overlap
Motif DE_60h DE_60h-Lhx3_MA0135.2 12 bp overlap
Motif DE_72h DE_72h-Lhx3_MA0135.2 12 bp overlap
MEF2C 4 datasets
Motif DE_36h DE_36h-MEF2C_MA0497.2 11 bp overlap
Motif DE_48h DE_48h-MEF2C_MA0497.2 11 bp overlap
Motif DE_60h DE_60h-MEF2C_MA0497.2 11 bp overlap
Motif DE_72h DE_72h-MEF2C_MA0497.2 11 bp overlap
MEIS1 4 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MEIS2 5 datasets
Motif DE_36h DE_36h-MEIS2_MA0774.1 8 bp overlap
Motif DE_48h DE_48h-MEIS2_MA0774.1 8 bp overlap
Motif DE_60h DE_60h-MEIS2_MA0774.1 8 bp overlap
Motif DE_72h DE_72h-MEIS2_MA0774.1 8 bp overlap
ChIP K-562 ENCSR851BNE.MEIS2.K-562 230 bp overlap
MEIS3 4 datasets
Motif DE_36h DE_36h-MEIS3_MA0775.2 7 bp overlap
Motif DE_48h DE_48h-MEIS3_MA0775.2 7 bp overlap
Motif DE_60h DE_60h-MEIS3_MA0775.2 7 bp overlap
Motif DE_72h DE_72h-MEIS3_MA0775.2 7 bp overlap
MYB 1 dataset
Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap
OTX1 4 datasets
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
PITX1 4 datasets
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX3 4 datasets
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
POU2F3 1 dataset
Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap
POU4F1 1 dataset
Motif DE_48h DE_48h-POU4F1_MA0790.2 12 bp overlap
POU4F3 1 dataset
Motif DE_48h DE_48h-POU4F3_MA0791.2 12 bp overlap
POU5F1 1 dataset
Motif DE_48h DE_48h-POU5F1_MA1115.2 7 bp overlap
PRDM1 3 datasets
Motif DE_48h DE_48h-PRDM1_MA0508.4 7 bp overlap
Motif DE_60h DE_60h-PRDM1_MA0508.4 7 bp overlap
Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap
Prdm4 3 datasets
Motif DE_36h DE_36h-Prdm4_MA1647.3 11 bp overlap
Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap
Motif DE_60h DE_60h-Prdm4_MA1647.3 11 bp overlap
RFX7 3 datasets
Motif DE_36h DE_36h-RFX7_MA1554.2 8 bp overlap
Motif DE_48h DE_48h-RFX7_MA1554.2 8 bp overlap
Motif DE_60h DE_60h-RFX7_MA1554.2 8 bp overlap
RHOXF1 4 datasets
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
RUNX3 3 datasets
Motif DE_36h DE_36h-RUNX3_MA0684.3 8 bp overlap
Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap
Motif DE_72h DE_72h-RUNX3_MA0684.3 8 bp overlap
Rfx6 3 datasets
Motif DE_36h DE_36h-Rfx6_MA1724.2 9 bp overlap
Motif DE_48h DE_48h-Rfx6_MA1724.2 9 bp overlap
Motif DE_60h DE_60h-Rfx6_MA1724.2 9 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 213 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 555 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 298 bp overlap
SMAD2_3 3 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 935 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 363 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 368 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 199 bp overlap
SOX17 2 datasets
ChIP DE_D2 DED2-SOX17_Batch_II 385 bp overlap
ChIP DE_D2 DED2-SOX17_Batch_II 246 bp overlap
SOX17_M 2 datasets
ChIP DE_D2 DED2-SOX17-M_Batch_II 507 bp overlap
ChIP DE_D2 DED2-SOX17-M_Batch_II 181 bp overlap
SOX21 3 datasets
Motif DE_48h DE_48h-SOX21_MA0866.1 15 bp overlap
Motif DE_60h DE_60h-SOX21_MA0866.1 15 bp overlap
Motif DE_72h DE_72h-SOX21_MA0866.1 15 bp overlap
SPI1 2 datasets
ChIP K-562 GSE70482.SPI1.K-562 177 bp overlap
ChIP K-562 ENCSR000BGW.SPI1.K-562 118 bp overlap
Sox1 3 datasets
Motif DE_48h DE_48h-Sox1_MA0870.1 15 bp overlap
Motif DE_60h DE_60h-Sox1_MA0870.1 15 bp overlap
Motif DE_72h DE_72h-Sox1_MA0870.1 15 bp overlap
Spi1 1 dataset
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 295 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 223 bp overlap
TRPS1 4 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ZBTB6 1 dataset
ChIP HEK293 GSE76494.ZBTB6.HEK293 173 bp overlap
ZBTB7B 3 datasets
Motif DE_36h DE_36h-ZBTB7B_MA0694.2 10 bp overlap
Motif DE_48h DE_48h-ZBTB7B_MA0694.2 10 bp overlap
Motif DE_60h DE_60h-ZBTB7B_MA0694.2 10 bp overlap
ZBTB7C 3 datasets
Motif DE_36h DE_36h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_48h DE_48h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_60h DE_60h-ZBTB7C_MA0695.2 8 bp overlap
ZNF140 1 dataset
Motif DE_48h DE_48h-ZNF140_MA1589.2 19 bp overlap
ZNF24 1 dataset
Motif DE_48h DE_48h-ZNF24_MA1124.1 13 bp overlap
ZNF35 1 dataset
Motif DE_48h DE_48h-ZNF35_MA2333.1 7 bp overlap
ZNF547 4 datasets
Motif DE_36h DE_36h-ZNF547_MA2334.1 13 bp overlap
Motif DE_48h DE_48h-ZNF547_MA2334.1 13 bp overlap
Motif DE_60h DE_60h-ZNF547_MA2334.1 13 bp overlap
Motif DE_72h DE_72h-ZNF547_MA2334.1 13 bp overlap
ZNF677 7 datasets
Motif DE_36h DE_36h-ZNF677_MA2101.1 12 bp overlap
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap
Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap
ZNF701 1 dataset
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
ZSCAN4 4 datasets
Motif DE_36h DE_36h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_48h DE_48h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_60h DE_60h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_72h DE_72h-ZSCAN4_MA1155.1 15 bp overlap
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