chr19 : 31,258,193 – 31,259,001

808 bp 73 TFs 1 linked gene

This 808 bp open chromatin element is linked to TSHZ3 and is bound by 73 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
TSHZ3		90.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

73 transcription factors

BRD4 1 dataset

ChIP RH4 GSE83726.BRD4.RH4 786 bp overlap

Bcl11B 1 dataset

Motif DE_60h DE_60h-Bcl11B_MA1989.2 9 bp overlap

CHD4 1 dataset

ChIP SCMC GSE155861.CHD4.SCMC 176 bp overlap

CTCF 1 dataset

ChIP RH4 GSE83726.CTCF.RH4 364 bp overlap

Crx 1 dataset

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

DNMT3B 1 dataset

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 283 bp overlap

ESRRA 1 dataset

Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_60h DE_60h-ETV2FOXI1_MA1942.2 11 bp overlap

EZH2 1 dataset

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 312 bp overlap

EZH2_phosphoT487 1 dataset

ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 148 bp overlap

FOSL1 1 dataset

ChIP WA01 ENCSR000BNS.FOSL1.WA01 146 bp overlap

FOXA1 1 dataset

Motif DE_60h DE_60h-FOXA1_MA0148.5 8 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 525 bp overlap

ChIP DE DE-FOXA2-2 505 bp overlap

FOXC1 1 dataset

Motif DE_60h DE_60h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap

FOXD3 1 dataset

Motif DE_60h DE_60h-FOXD3_MA0041.3 14 bp overlap

FOXF2 1 dataset

Motif DE_60h DE_60h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_60h DE_60h-FOXG1_MA0613.1 8 bp overlap

FOXH1 1 dataset

Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap

FOXK1 1 dataset

Motif DE_60h DE_60h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_60h DE_60h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_60h DE_60h-FOXL1_MA0033.2 7 bp overlap

FOXO4 1 dataset

Motif DE_60h DE_60h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_60h DE_60h-FOXO6_MA0849.1 7 bp overlap

FOXP2 1 dataset

Motif DE_60h DE_60h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_60h DE_60h-FOXP3_MA0850.1 7 bp overlap

Foxf1 1 dataset

Motif DE_60h DE_60h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_60h DE_60h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_60h DE_60h-Foxj3_MA0851.2 9 bp overlap

Foxo1 1 dataset

Motif DE_60h DE_60h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_60h DE_60h-Foxo3_MA0157.4 7 bp overlap

Foxq1 1 dataset

Motif DE_60h DE_60h-Foxq1_MA0040.2 10 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 377 bp overlap

ChIP DE DE-GATA4-2 448 bp overlap

ChIP foregut GSE117136.GATA4.foregut 267 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 289 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 337 bp overlap

ChIP DE DE-GATA6-2 514 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 328 bp overlap

GSC 1 dataset

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

Gata3 1 dataset

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

HNF1A 1 dataset

Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap

HNF1B 1 dataset

Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap

Hmx2 1 dataset

Motif DE_60h DE_60h-Hmx2_MA0897.2 15 bp overlap

Hoxa13 1 dataset

Motif DE_60h DE_60h-Hoxa13_MA0650.4 8 bp overlap

IRF7 1 dataset

Motif DE_60h DE_60h-IRF7_MA0772.2 13 bp overlap

MED1 1 dataset

ChIP RH4 GSE83726.MED1.RH4 321 bp overlap

MYCN 1 dataset

ChIP RH4 GSE83726.MYCN.RH4 494 bp overlap

MYOD1 2 datasets

ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 378 bp overlap

ChIP RH4 GSE83726.MYOD1.RH4 309 bp overlap

MYOG 2 datasets

ChIP RH30_DMSO GSE85169.MYOG.RH30_DMSO 251 bp overlap

ChIP RH4 GSE83726.MYOG.RH4 791 bp overlap

NKX2-3 1 dataset

Motif DE_60h DE_60h-NKX2-3_MA0672.2 8 bp overlap

NKX2-4 1 dataset

Motif DE_60h DE_60h-NKX2-4_MA2003.2 8 bp overlap

NKX2-8 1 dataset

Motif DE_60h DE_60h-NKX2-8_MA0673.2 8 bp overlap

Nkx2-1 1 dataset

Motif DE_60h DE_60h-Nkx2-1_MA1994.2 7 bp overlap

OTX1 1 dataset

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

PBX1 1 dataset

ChIP RCH-ACV GSE85988.PBX1.RCH-ACV 407 bp overlap

PITX1 1 dataset

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

PKNOX1 6 datasets

ChIP HEK293T ENCFF174WDB 179 bp overlap

ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 338 bp overlap

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 309 bp overlap

ChIP K562 ENCFF236IUS 457 bp overlap

ChIP MCF-7 ENCFF116OCS 411 bp overlap

ChIP MCF-7 ENCSR986XYK.PKNOX1.MCF-7 376 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 385 bp overlap

POU3F3 1 dataset

Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap

RAD21 2 datasets

ChIP RH4 GSE83726.RAD21.RH4 392 bp overlap

ChIP RH4 GSE83726.RAD21.RH4 156 bp overlap

RBBP4 1 dataset

ChIP SCMC GSE155861.RBBP4.SCMC 135 bp overlap

RHOXF1 1 dataset

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 160 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 380 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 217 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 264 bp overlap

STAT1::STAT2 1 dataset

Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap

Stat5a 1 dataset

Motif DE_60h DE_60h-Stat5a_MA1624.2 9 bp overlap

TRPS1 1 dataset

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 471 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 109 bp overlap

ZNF274 3 datasets

ChIP HEK293 ENCFF742VRL 327 bp overlap

ChIP HEK293 ENCFF742VRL 125 bp overlap

ChIP HEK293 ENCSR178QVJ.ZNF274.HEK293 280 bp overlap

ZNF410 1 dataset

Motif DE_60h DE_60h-ZNF410_MA0752.2 16 bp overlap

ZNF766 1 dataset

Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap

Zfp335 1 dataset

Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap