chr18 : 1,505,772 – 1,506,242

470 bp 69 TFs 1 linked gene

This 470 bp open chromatin element is linked to ENSG00000266602 and is bound by 69 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000266602		2.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

69 transcription factors

ASCL1 1 dataset

ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 120 bp overlap

ATF3 1 dataset

ChIP HCT-116_CAMP GSE74355.ATF3.HCT-116_CAMP 102 bp overlap

BRD4 3 datasets

ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.BRD4.MCF-7_ARID1A-KO_4-OHT 470 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.BRD4.MCF-7_parental_4-hydroxytamoxifen 308 bp overlap

ChIP PC-3_GDC-R_SAHA GSE137207.BRD4.PC-3_GDC-R_SAHA 300 bp overlap

CTCF 1 dataset

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 209 bp overlap

EOMES 2 datasets

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

FOS 2 datasets

ChIP MCF-10A ENCSR000DON.FOS.MCF-10A 221 bp overlap

ChIP MCF-7 ENCSR569XNP.FOS.MCF-7 225 bp overlap

FOXO1-PAX3 1 dataset

ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 190 bp overlap

GATA6 3 datasets

ChIP DE_D1 S41-DE-d1-GATA6-exp2 303 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 293 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 341 bp overlap

Gli1 1 dataset

Motif DE_12h DE_12h-Gli1_MA1990.2 10 bp overlap

Hand1 2 datasets

Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap

IRF3 1 dataset

Motif DE_12h DE_12h-IRF3_MA1418.2 17 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 345 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 470 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 470 bp overlap

KLF4 1 dataset

ChIP HAP1 GSE130417.KLF4.HAP1 205 bp overlap

MGA 1 dataset

Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap

MTF2 1 dataset

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 339 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 336 bp overlap

NCOA3 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 128 bp overlap

NFIA 1 dataset

Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap

NFIX 1 dataset

Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap

PDX1 1 dataset

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 150 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU5F1 7 datasets

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 248 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 396 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 154 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 319 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 351 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 264 bp overlap

PRDM1 1 dataset

ChIP fetal_testis GSE100639.PRDM1.fetal_testis 108 bp overlap

PRDM9 1 dataset

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 1 dataset

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 407 bp overlap

Runx1 1 dataset

Motif DE_12h DE_12h-Runx1_MA0002.3 9 bp overlap

SCRT1 1 dataset

Motif DE_12h DE_12h-SCRT1_MA0743.3 10 bp overlap

SCRT2 1 dataset

Motif DE_12h DE_12h-SCRT2_MA0744.3 10 bp overlap

SMAD2 4 datasets

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 466 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 366 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 411 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 470 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 379 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 387 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 455 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 287 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 364 bp overlap

SMAD3 2 datasets

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 139 bp overlap

ChIP PC-3_hypoxia GSE106305.SMAD3.PC-3_hypoxia 384 bp overlap

SMAD3-HIF1A 1 dataset

ChIP PC-3_hypoxia GSE106305.SMAD3-HIF1A.PC-3_hypoxia 174 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 216 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 205 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 234 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 273 bp overlap

SOX10 1 dataset

Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap

SOX2 1 dataset

ChIP hESC GSE18292.SOX2.hESC 113 bp overlap

SOX4 1 dataset

Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap

SOX8 1 dataset

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 223 bp overlap

SP4 1 dataset

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

STAT1::STAT2 1 dataset

Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap

STAT3 2 datasets

ChIP MCF-10A ENCSR000DOQ.STAT3.MCF-10A 154 bp overlap

ChIP MCF10A-Er-Src_TAM GSE115597.STAT3.MCF10A-Er-Src_TAM 157 bp overlap

Sox17 1 dataset

Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap

Sox5 1 dataset

Motif DE_12h DE_12h-Sox5_MA0087.3 8 bp overlap

Sox7 1 dataset

Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 227 bp overlap

TBR1 2 datasets

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TBX3 2 datasets

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TBX5 1 dataset

Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap

TP53 1 dataset

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 249 bp overlap

Tbx6 2 datasets

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

ZKSCAN3 1 dataset

Motif DE_12h DE_12h-ZKSCAN3_MA1973.2 14 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF263 1 dataset

Motif DE_12h DE_12h-ZNF263_MA0528.3 7 bp overlap

ZNF384 1 dataset

Motif DE_12h DE_12h-ZNF384_MA1125.2 8 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF766 1 dataset

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap

Zic2 1 dataset

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap