chr15:50,466,510–50,467,099

chr15 : 50,466,510 – 50,467,099

589 bp 48 TFs 8 linked genes

This 589 bp open chromatin element is linked to 8 target genes and is bound by 48 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000242737		at TSS	At TSS	Proximity
USP8		42.3 kb	Distal	Multiome
GABPB1-AS1		111.5 kb	Distal	Multiome
GABPB1		111.6 kb	Distal	Multiome
GABPB1-IT1		111.9 kb	Distal	Multiome
TRPM7		220.1 kb	Distal	Multiome
SLC27A2		284.5 kb	Distal	Multiome
SPPL2A		299.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

48 transcription factors

ChIP MCF-7_TCDD_45min GSE90550.AHR.MCF-7_TCDD_45min 178 bp overlap

ChIP LNCaP ERP003503.AR.LNCaP 142 bp overlap

ChIP LNCaP_DHT GSE125245.AR.LNCaP_DHT 206 bp overlap

ChIP LNCaP_FOXA1 ERP003503.AR.LNCaP_FOXA1 191 bp overlap

ChIP LNCaP_SHFOXA1_R1881 GSE37345.AR.LNCaP_SHFOXA1_R1881 155 bp overlap

ChIP LNCaP_Talen_DHT GSE89938.AR.LNCaP_Talen_DHT 162 bp overlap

ChIP LNCaP_r1881 GSE94682.AR.LNCaP_r1881 182 bp overlap

ChIP MCF-7 GSE48930.AR.MCF-7 163 bp overlap

ChIP VCaP GSE148358.AR.VCaP 184 bp overlap

ChIP prostate-cancer_C4-2-CON GSE136128.AR.prostate-cancer_C4-2-CON 134 bp overlap

ChIP prostate-cancer_PDX_35 GSE130408.AR.prostate-cancer_PDX_35 220 bp overlap

ChIP prostate-cancer_PDX_70 GSE130408.AR.prostate-cancer_PDX_70 200 bp overlap

ASH2L 2 datasets

ChIP VCaP_R1881 GSE60841.ASH2L.VCaP_R1881 257 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 300 bp overlap

BAF155 2 datasets

ChIP VCaP_shARID1A GSE110655.BAF155.VCaP_shARID1A 208 bp overlap

ChIP VCaP_shERG GSE110655.BAF155.VCaP_shERG 228 bp overlap

BCL11A 1 dataset

Motif DE_12h DE_12h-BCL11A_MA2324.1 7 bp overlap

BCOR 3 datasets

ChIP VCaP_EtOH GSE122572.BCOR.VCaP_EtOH 160 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 211 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 232 bp overlap

ChIP hESC GSE33281.BRD4.hESC 79 bp overlap

CREB1 2 datasets

ChIP LNCaP-abl GSE63034.CREB1.LNCaP-abl 129 bp overlap

ChIP LNCaP-abl_SHFOXA1 GSE63034.CREB1.LNCaP-abl_SHFOXA1 231 bp overlap

CTBP2 1 dataset

ChIP MCF-7 GSE107013.CTBP2.MCF-7 111 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF262VBH 338 bp overlap

ChIP VCaP GSE28950.ERG.VCaP 191 bp overlap

ChIP VCaP_DHAT_18H GSE28950.ERG.VCaP_DHAT_18H 180 bp overlap

ChIP VCaP_DHAT_2H GSE28950.ERG.VCaP_DHAT_2H 144 bp overlap

ChIP VCaP_shARID1A GSE110655.ERG.VCaP_shARID1A 209 bp overlap

ChIP VCaP_shERG GSE110655.ERG.VCaP_shERG 209 bp overlap

ESR1 3 datasets

ChIP MCF-7 ERP000209.ESR1.MCF-7 119 bp overlap

ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 205 bp overlap

ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 213 bp overlap

ETV1 2 datasets

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

ChIP MDA-Pca-2b GSE106624.ETV1.MDA-Pca-2b 146 bp overlap

FOXA1 2 datasets

ChIP LNCaP_R1881 GSE69043.FOXA1.LNCaP_R1881 139 bp overlap

ChIP LNCaP_SHGATA2_R1881 GSE69043.FOXA1.LNCaP_SHGATA2_R1881 125 bp overlap

GRHL1 2 datasets

ChIP MCF-7 GSE140185.GRHL1.MCF-7 343 bp overlap

ChIP MCF-7_ARID1A-KO GSE140185.GRHL1.MCF-7_ARID1A-KO 260 bp overlap

GRHL2 5 datasets

ChIP LNCaP GSE80256.GRHL2.LNCaP 299 bp overlap

ChIP MCF-7 GSE109820.GRHL2.MCF-7 261 bp overlap

ChIP MCF-7 GSE99680.GRHL2.MCF-7 217 bp overlap

ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 213 bp overlap

ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 281 bp overlap

HOXB13 2 datasets

ChIP prostate-cancer_PDX_141 GSE130408.HOXB13.prostate-cancer_PDX_141 81 bp overlap

ChIP prostate-cancer_PDX_70 GSE130408.HOXB13.prostate-cancer_PDX_70 79 bp overlap

Motif DE_12h DE_12h-HSF2_MA0770.1 13 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 1 dataset

Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 281 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 281 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 305 bp overlap

ChIP LNCaP_MYC GSE73994.MYC.LNCaP_MYC 137 bp overlap

ChIP MCF-7 ENCFF542NWJ 305 bp overlap

ChIP MCF-7 ENCSR000DMQ.MYC.MCF-7 146 bp overlap

NANOG 5 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 499 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 199 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 149 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 137 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 535 bp overlap

NFATC3 1 dataset

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 165 bp overlap

Nfat5 1 dataset

Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap

Nfatc1 1 dataset

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

POU5F1 3 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 426 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 177 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 333 bp overlap

RUNX1 1 dataset

ChIP VCaP_DHT24H GSE58428.RUNX1.VCaP_DHT24H 395 bp overlap

Runx1 1 dataset

Motif DE_12h DE_12h-Runx1_MA0002.3 9 bp overlap

SMAD2 2 datasets

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 484 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 290 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 376 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 271 bp overlap

SMAD2_3 2 datasets

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 285 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 465 bp overlap

SMARCA4 4 datasets

ChIP MCF-7 GSE140185.SMARCA4.MCF-7 260 bp overlap

ChIP MCF-7_parental GSE123284.SMARCA4.MCF-7_parental 232 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 159 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 169 bp overlap

SMARCC1 1 dataset

ChIP ESC S25-ESC-d0-BAF155-exp1 445 bp overlap

SMARCD3 1 dataset

ChIP MCF-7 GSE124225.SMARCD3.MCF-7 173 bp overlap

SMC1A 1 dataset

ChIP MCF-7_EtOH GSE115602.SMC1A.MCF-7_EtOH 162 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 214 bp overlap

STAG1 1 dataset

ChIP MCF-7 ERP000209.STAG1.MCF-7 127 bp overlap

STAT3 1 dataset

Motif DE_12h DE_12h-STAT3_MA0144.3 9 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 162 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 159 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 110 bp overlap

ChIP MCF-7 ENCFF783FFV 244 bp overlap

ZNF707 1 dataset

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

ZNF93 1 dataset

Motif DE_12h DE_12h-ZNF93_MA1721.2 14 bp overlap

Zic1::Zic2 1 dataset

Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 2 datasets

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap