chr14 : 76,987,872 – 76,988,397
525 bp 38 TFs 5 linked genes
This 525 bp open chromatin element is linked to 5 target genes and is bound by 38 transcription factors.
Linked Genes
5 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
IRF2BPL 40.6 kb Distal Multiome
CIPC 110.1 kb Distal Multiome
ANGEL1 175.3 kb Distal Multiome
VASH1 226.7 kb Distal Multiome
NGB 283.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr14:76,982,872 – 76,993,397
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
38 transcription factors
Source
Cell type
CTCF 1 dataset
ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 299 bp overlap
DPF2 1 dataset
ChIP MCF-7 ENCSR234VCE.DPF2.MCF-7 267 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 300 bp overlap
ESR1 27 datasets
ChIP MCF-7 GSE128445.ESR1.MCF-7 191 bp overlap
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 94 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 152 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 453 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 205 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 234 bp overlap
ChIP MCF-7_jc5855 GSE126004.ESR1.MCF-7_jc5855 226 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 322 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 165 bp overlap
ChIP MCF-7_shCtrl GSE125594.ESR1.MCF-7_shCtrl 148 bp overlap
ChIP MCF-7_shFbxo GSE119702.ESR1.MCF-7_shFbxo 183 bp overlap
ChIP MCF-7_shFbxo_E2 GSE119702.ESR1.MCF-7_shFbxo_E2 183 bp overlap
ChIP T-47D ENCSR000BKN.ESR1.T-47D 118 bp overlap
ChIP T-47D GSE148277.ESR1.T-47D 389 bp overlap
ChIP T-47D ENCSR000BJS.ESR1.T-47D 183 bp overlap
ChIP T-47D ENCSR000BKN.ESR1.T-47D 150 bp overlap
ChIP T-47D_D538G GSE148277.ESR1.T-47D_D538G 288 bp overlap
ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 374 bp overlap
ChIP T-47D_JC4727 GSE126004.ESR1.T-47D_JC4727 195 bp overlap
ChIP T-47D_JC4732 GSE126004.ESR1.T-47D_JC4732 245 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 508 bp overlap
ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 525 bp overlap
ChIP T-47D_flp-ctrl GSE99479.ESR1.T-47D_flp-ctrl 310 bp overlap
ChIP T-47D_siCont-IL6 GSE126004.ESR1.T-47D_siCont-IL6 331 bp overlap
ChIP T-47D_siFOXA1-IL6 GSE126004.ESR1.T-47D_siFOXA1-IL6 165 bp overlap
ChIP T-47D_siFOXA1-Veh GSE126004.ESR1.T-47D_siFOXA1-Veh 174 bp overlap
ChIP breast_tumor_Male_5 GSE104399.ESR1.breast_tumor_Male_5 151 bp overlap
ESR1_Y537C 1 dataset
ChIP SUM44PE__ESR1_mutant_LTED GSE100074.ESR1_Y537C.SUM44PE__ESR1_mutant_LTED 390 bp overlap
ESR1_Y537S 2 datasets
ChIP T-47D_E2 GSE94493.ESR1_Y537S.T-47D_E2 130 bp overlap
ChIP T-47D_dox_E2 GSE94493.ESR1_Y537S.T-47D_dox_E2 145 bp overlap
ESR1_pS118 1 dataset
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 209 bp overlap
FOXA1 4 datasets
ChIP T-47D_JC4743 GSE126004.FOXA1.T-47D_JC4743 367 bp overlap
ChIP T-47D_JC4747 GSE126004.FOXA1.T-47D_JC4747 304 bp overlap
ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 204 bp overlap
ChIP primary-breast-cancer_B1_DSG GSE114737.FOXA1.primary-breast-cancer_B1_DSG 217 bp overlap
FOXA2 1 dataset
ChIP DE DE-FOXA2-1 312 bp overlap
GATA3 4 datasets
ChIP MCF-7 ENCFF352QVM 463 bp overlap
ChIP T-47D GSE51274.GATA3.T-47D 258 bp overlap
ChIP T-47D ENCSR000BMX.GATA3.T-47D 206 bp overlap
ChIP T-47D_sc GSE122847.GATA3.T-47D_sc 308 bp overlap
GATA3_Nter 2 datasets
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 173 bp overlap
ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 220 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 318 bp overlap
ChIP DE DE-GATA4-2 424 bp overlap
GATA6 8 datasets
ChIP DE DE-GATA6-1 331 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 403 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 260 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 317 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 471 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 364 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 402 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 309 bp overlap
GLIS1 2 datasets
ChIP HEK293 ENCFF299RSE 366 bp overlap
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 264 bp overlap
GLIS3 1 dataset
ChIP H9_plus GSE109562.GLIS3.H9_plus 253 bp overlap
GRHL2 2 datasets
ChIP LNCaP GSE80256.GRHL2.LNCaP 202 bp overlap
ChIP T-47D GSE99680.GRHL2.T-47D 218 bp overlap
HDAC3 1 dataset
ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 250 bp overlap
HSF1 1 dataset
ChIP MO91_CHX_10UM GSE45852.HSF1.MO91_CHX_10UM 178 bp overlap
JUN 3 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 356 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 412 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 384 bp overlap
MED1 1 dataset
ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 266 bp overlap
NCOA3 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 146 bp overlap
NR3C1 1 dataset
ChIP T47D-A1-2_Dex GSE112491.NR3C1.T47D-A1-2_Dex 259 bp overlap
NUTM1 1 dataset
ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 186 bp overlap
PARP1 1 dataset
ChIP MCF-10A GSE93038.PARP1.MCF-10A 291 bp overlap
PGR 2 datasets
ChIP T-47D_PROG GSE68355.PGR.T-47D_PROG 322 bp overlap
ChIP T-47D_R5020 GSE68355.PGR.T-47D_R5020 377 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 376 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 455 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 525 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 492 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 432 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 380 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 381 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 525 bp overlap
SMAD3 1 dataset
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 149 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 180 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 170 bp overlap
SMARCB1 2 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 380 bp overlap
ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 347 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 189 bp overlap
STAT3 9 datasets
ChIP T-47D_JC4735 GSE126004.STAT3.T-47D_JC4735 223 bp overlap
ChIP T-47D_JC4739 GSE126004.STAT3.T-47D_JC4739 187 bp overlap
ChIP T-47D_JC4741 GSE126004.STAT3.T-47D_JC4741 320 bp overlap
ChIP T-47D_JC4751 GSE126004.STAT3.T-47D_JC4751 293 bp overlap
ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 267 bp overlap
ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 265 bp overlap
ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 335 bp overlap
ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 341 bp overlap
ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 360 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 193 bp overlap
TEAD4 2 datasets
ChIP MCF-7_BLRP_WT_E2 GSE125594.TEAD4.MCF-7_BLRP_WT_E2 139 bp overlap
ChIP MCF-7_BLRP_WT_Veh GSE125594.TEAD4.MCF-7_BLRP_WT_Veh 320 bp overlap
TFAP2A 1 dataset
ChIP MCF-7_E2 GSE60270.TFAP2A.MCF-7_E2 86 bp overlap
TFAP2C 1 dataset
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 218 bp overlap
YY1AP1 2 datasets
ChIP MCF-7_E2 GSE125594.YY1AP1.MCF-7_E2 212 bp overlap
ChIP T-47D_E2 GSE125594.YY1AP1.T-47D_E2 308 bp overlap
Huangfu Lab · Publications · Resources · Contact