Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

52 transcription factors

ARNT 1 dataset

ChIP A-549 GSE85352.ARNT.A-549 241 bp overlap

ARNTL 1 dataset

ChIP U2OS_DMOG GSE85096.ARNTL.U2OS_DMOG 209 bp overlap

ASCL1 1 dataset

ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 163 bp overlap

ASXL3 1 dataset

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 674 bp overlap

BAP1 1 dataset

ChIP NCI-H1963_shNONT GSE145028.BAP1.NCI-H1963_shNONT 284 bp overlap

BCL3 2 datasets

ChIP GM12878 ENCFF854PAY 351 bp overlap

ChIP GM12878 ENCSR000BNQ.BCL3.GM12878 508 bp overlap

BRD4 5 datasets

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 565 bp overlap

ChIP NCI-H1963_dBET6 GSE145028.BRD4.NCI-H1963_dBET6 651 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 344 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 712 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 377 bp overlap

CDX2 4 datasets

ChIP LS180 GSE31939.CDX2.LS180 86 bp overlap

ChIP LS180 GSE31939.CDX2.LS180 131 bp overlap

ChIP LS180_125 GSE31939.CDX2.LS180_125 96 bp overlap

ChIP adult-duodenal-cell GSE115314.CDX2.adult-duodenal-cell 215 bp overlap

CHD7 2 datasets

ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 356 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 587 bp overlap

CTCF 4 datasets

Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap

ChIP OCI-LY7 ENCFF086AXQ 77 bp overlap

ChIP VCaP ENCFF858YQT 132 bp overlap

ChIP neural ENCSR822CEA.CTCF.neural 242 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 156 bp overlap

EP300 1 dataset

ChIP neural ENCSR843ZUP.EP300.neural 474 bp overlap

EZH2 1 dataset

ChIP neural progenitor cell ENCFF018MKA 341 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 297 bp overlap

FEZF1 4 datasets

ChIP HEK293 ENCFF528YED 276 bp overlap

ChIP HEK293 ENCFF528YED 139 bp overlap

ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 442 bp overlap

ChIP HEK293 GSE76494.FEZF1.HEK293 394 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 633 bp overlap

ChIP DE DE-FOXA2-2 673 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 620 bp overlap

ChIP DE DE-GATA4-2 695 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 588 bp overlap

ChIP DE DE-GATA6-2 693 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 263 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 383 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 270 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 392 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 408 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 364 bp overlap

Hand1 1 dataset

Motif DE_48h DE_48h-Hand1_MA2123.1 9 bp overlap

MAFB 1 dataset

ChIP islet ERP004003.MAFB.islet 228 bp overlap

MAX 1 dataset

ChIP NCI-H128 GSE41105.MAX.NCI-H128 309 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 267 bp overlap

NFATC1 1 dataset

ChIP GM12878 ENCSR000BQL.NFATC1.GM12878 382 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 176 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 398 bp overlap

NR2F2 1 dataset

ChIP liver ENCSR338MMB.NR2F2.liver 155 bp overlap

ONECUT1 2 datasets

ChIP H9 ERP004206.ONECUT1.H9 290 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 267 bp overlap

PAF1 1 dataset

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 356 bp overlap

PBX3 1 dataset

ChIP GM12878 ENCSR000BGR.PBX3.GM12878 105 bp overlap

PDX1 1 dataset

ChIP hiPSC GSE125768.PDX1.hiPSC 297 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 119 bp overlap

POLR2G 1 dataset

ChIP HepG2 ENCFF508UTS 609 bp overlap

Plagl1 1 dataset

Motif DE_48h DE_48h-Plagl1_MA1615.2 8 bp overlap

RARA 2 datasets

ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 335 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 569 bp overlap

RBPJ 4 datasets

Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap

ChIP GIC GSE79734.RBPJ.GIC 379 bp overlap

ChIP GSC8-11_dasatinib GSE74557.RBPJ.GSC8-11_dasatinib 552 bp overlap

ChIP GSC8-11_dasatinib GSE74557.RBPJ.GSC8-11_dasatinib 98 bp overlap

RELA 2 datasets

ChIP HEK293_30_min GSE89017.RELA.HEK293_30_min 305 bp overlap

ChIP HEK293_60_min GSE89017.RELA.HEK293_60_min 314 bp overlap

REST 1 dataset

ChIP neural ENCSR000BTV.REST.neural 355 bp overlap

SIX2 3 datasets

ChIP HEK GSE73865.SIX2.HEK 246 bp overlap

ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 109 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 120 bp overlap

SMAD2 1 dataset

Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 550 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 339 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 484 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 452 bp overlap

SMARCA4 1 dataset

ChIP NSC GSE125033.SMARCA4.NSC 243 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_shSNAI2 GSE137168.SNAI2.SMS-CTR_shSNAI2 209 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 351 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 657 bp overlap

SOX2 2 datasets

ChIP HNSC GSE69479.SOX2.HNSC 608 bp overlap

ChIP hiPSC_KDP53 GSE67282.SOX2.hiPSC_KDP53 212 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 248 bp overlap

TCF3 1 dataset

ChIP GM12878 ENCSR000BQT.TCF3.GM12878 139 bp overlap

YY1 1 dataset

ChIP K-562 ENCSR000BKU.YY1.K-562 172 bp overlap

ZIC5 1 dataset

Motif DE_48h DE_48h-ZIC5_MA1584.2 15 bp overlap

ZNF530 1 dataset

Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap

Zfp809 1 dataset

Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap

Gene	Dist. to TSS	Distance	Link type
PPP2R5E	180.7 kb	Distal	Multiome
WDR89	279.2 kb	Distal	Multiome
ENSG00000274015	279.4 kb	Distal	Multiome

Genome Browser