chr14 : 54,392,880 – 54,394,206

1,326 bp 67 TFs 1 linked gene

This 1.3 kb open chromatin element is linked to CDKN3 and is bound by 67 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
CDKN3		2.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

67 transcription factors

AATF 1 dataset

ChIP NALM-6 GSE93626.AATF.NALM-6 208 bp overlap

ASCL1 1 dataset

Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap

Ahr::Arnt 1 dataset

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

BHLHE22 2 datasets

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

BRD4 3 datasets

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 286 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 282 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 190 bp overlap

Bhlha15 1 dataset

Motif DE_12h DE_12h-Bhlha15_MA1472.3 8 bp overlap

CDK9 1 dataset

ChIP HCT-116 GSE72622.CDK9.HCT-116 171 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 261 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 124 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 332 bp overlap

EGR1 1 dataset

Motif DE_12h DE_12h-EGR1_MA0162.5 10 bp overlap

EGR3 1 dataset

Motif DE_12h DE_12h-EGR3_MA0732.2 11 bp overlap

EGR4 1 dataset

Motif DE_12h DE_12h-EGR4_MA0733.2 11 bp overlap

ELF2 1 dataset

Motif DE_12h DE_12h-ELF2_MA1483.3 10 bp overlap

ELF4 1 dataset

Motif DE_12h DE_12h-ELF4_MA0641.1 12 bp overlap

ERG 1 dataset

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 340 bp overlap

ESR1 2 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 207 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 419 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 695 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

JUN 1 dataset

ChIP ESC S24-ESC-d0-JUN-exp1 281 bp overlap

KLF1 1 dataset

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

KLF11 1 dataset

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

KLF12 1 dataset

Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap

KLF13 1 dataset

Motif DE_12h DE_12h-KLF13_MA0657.2 17 bp overlap

KLF14 1 dataset

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

KLF15 1 dataset

Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap

KLF16 1 dataset

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

KLF2 1 dataset

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

KLF6 1 dataset

Motif DE_12h DE_12h-KLF6_MA1517.2 9 bp overlap

KLF7 1 dataset

Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap

KLF9 1 dataset

Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap

MAX 2 datasets

ChIP H1 ENCFF914VQY 357 bp overlap

MYF5 1 dataset

Motif DE_12h DE_12h-MYF5_MA1641.2 8 bp overlap

MYOD1 1 dataset

Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap

MYOG 1 dataset

Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap

NANOG 1 dataset

ChIP WA01 ERP004238.NANOG.WA01 253 bp overlap

NHLH1 1 dataset

Motif DE_12h DE_12h-NHLH1_MA0048.3 9 bp overlap

NHLH2 1 dataset

Motif DE_12h DE_12h-NHLH2_MA1529.2 16 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 395 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 641 bp overlap

Neurod2 2 datasets

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 357 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 293 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 454 bp overlap

Olig2 2 datasets

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 909 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 218 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 937 bp overlap

Ptf1A 1 dataset

Motif DE_12h DE_12h-Ptf1A_MA1619.2 8 bp overlap

REST 1 dataset

Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 779 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 881 bp overlap

SMARCC1 1 dataset

ChIP ESC S25-ESC-d0-BAF155-exp1 444 bp overlap

SP3 1 dataset

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

SP4 1 dataset

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

SP8 1 dataset

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

SP9 1 dataset

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

SPDEF 1 dataset

Motif DE_12h DE_12h-SPDEF_MA0686.2 10 bp overlap

SREBP2 3 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 843 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 411 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 218 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 247 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TCF4 1 dataset

Motif DE_12h DE_12h-TCF4_MA0830.3 8 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 293 bp overlap

TRIM28 2 datasets

ChIP HCT-116 GSE72622.TRIM28.HCT-116 195 bp overlap

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 151 bp overlap

Tcf12 2 datasets

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Twist2 2 datasets

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

WDR5 1 dataset

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 811 bp overlap

ZBED4 1 dataset

Motif DE_12h DE_12h-ZBED4_MA2328.1 10 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZNF682 1 dataset

Motif DE_12h DE_12h-ZNF682_MA1599.2 11 bp overlap

ZNF692 1 dataset

Motif DE_12h DE_12h-ZNF692_MA1986.2 8 bp overlap