chr12 : 25,876,360 – 25,876,912
552 bp 39 TFs 4 linked genes
This 552 bp open chromatin element is linked to 4 target genes and is bound by 39 transcription factors.
Linked Genes
4 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000256256 8.9 kb Proximal Proximity
RASSF8-AS1 81.9 kb Distal Multiome
RASSF8 82.0 kb Distal Multiome
LMNTD1 246.0 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:25,871,360 – 25,881,912
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
39 transcription factors
Source
Cell type
CDX2 1 dataset
ChIP Caco-2_PROLIF GSE23436.CDX2.Caco-2_PROLIF 148 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 322 bp overlap
ESR1 1 dataset
ChIP MCF-7 GSE76893.ESR1.MCF-7 325 bp overlap
FOXA1 4 datasets
ChIP ZR751 GSE72249.FOXA1.ZR751 122 bp overlap
ChIP ZR751_DEX GSE72249.FOXA1.ZR751_DEX 109 bp overlap
ChIP ZR751_E2 GSE72249.FOXA1.ZR751_E2 119 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 302 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 212 bp overlap
ChIP DE DE-FOXA2-1 552 bp overlap
ChIP DE DE-FOXA2-2 552 bp overlap
GATA1 2 datasets
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 207 bp overlap
ChIP K562 ENCFF094CMK 251 bp overlap
GATA2 5 datasets
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 383 bp overlap
ChIP WA09 GSE105081.GATA2.WA09 287 bp overlap
GATA3 2 datasets
ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 140 bp overlap
ChIP WA09 GSE105081.GATA3.WA09 189 bp overlap
GATA4 14 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 180 bp overlap
ChIP DE DE-GATA4-1 552 bp overlap
ChIP DE DE-GATA4-2 552 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 303 bp overlap
ChIP YCC-3 GSE51705.GATA4.YCC-3 247 bp overlap
ChIP foregut GSE117136.GATA4.foregut 552 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 552 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 509 bp overlap
GATA5 6 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 24 datasets
ChIP AGS GSE51705.GATA6.AGS 327 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 338 bp overlap
ChIP DE DE-GATA6-1 545 bp overlap
ChIP DE DE-GATA6-2 552 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 552 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 552 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 552 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 552 bp overlap
ChIP ESO-26 GSE132680.GATA6.ESO-26 337 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 552 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 552 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 224 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 552 bp overlap
ChIP foregut GSE117136.GATA6.foregut 534 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 510 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 552 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 552 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 495 bp overlap
GRHL2 2 datasets
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
Gata3 6 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HNF4A 1 dataset
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 174 bp overlap
JUN 2 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 288 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 322 bp overlap
Mecom 3 datasets
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
ONECUT1 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 480 bp overlap
ONECUT2 1 dataset
ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 331 bp overlap
PDX1 2 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 338 bp overlap
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 354 bp overlap
Pou5f1::Sox2 2 datasets
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap
RARA 1 dataset
ChIP hiPSC_D5 GSE132532.RARA.hiPSC_D5 320 bp overlap
SMAD2 3 datasets
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 4 datasets
ChIP HGrC1_EV-TGF GSE138496.SMAD2-3.HGrC1_EV-TGF 91 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 552 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 552 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 406 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 402 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 447 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 423 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 410 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 543 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 227 bp overlap
SMARCC1 2 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 305 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 371 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 324 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 384 bp overlap
SOX21 1 dataset
Motif DE_60h DE_60h-SOX21_MA0866.1 15 bp overlap
SPI1 1 dataset
ChIP K-562 GSE70482.SPI1.K-562 134 bp overlap
TAL1 1 dataset
ChIP ProEs GSE59087.TAL1.ProEs 215 bp overlap
TEAD1 3 datasets
Motif DE_48h DE_48h-TEAD1_MA0090.4 9 bp overlap
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap
TEAD2 3 datasets
Motif DE_48h DE_48h-TEAD2_MA1121.2 7 bp overlap
Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap
Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap
TEAD3 3 datasets
Motif DE_48h DE_48h-TEAD3_MA0808.1 8 bp overlap
Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap
Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap
TEAD4 3 datasets
Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap
Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap
Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap
TFAP2A 1 dataset
ChIP WA09 GSE105081.TFAP2A.WA09 286 bp overlap
TRPS1 6 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ZNF281 2 datasets
ChIP K562 ENCFF594VNM 470 bp overlap
ChIP K562 ENCFF594VNM 270 bp overlap
ZNF75D 2 datasets
Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_60h DE_60h-ZNF75D_MA1601.2 12 bp overlap
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