chr12 : 15,781,389 – 15,781,618
229 bp 36 TFs 1 linked gene
This 229 bp open chromatin element is linked to EPS8 and is bound by 36 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
EPS8 7.8 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:15,776,389 – 15,786,618
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
36 transcription factors
Source
Cell type
AR 3 datasets
ChIP MCF-7 ERP001226.AR.MCF-7 101 bp overlap
ChIP VCaP_DHT24H_SHFOXA1 GSE58428.AR.VCaP_DHT24H_SHFOXA1 208 bp overlap
ChIP VCaP_DHT24H_SHFOXP1 GSE58428.AR.VCaP_DHT24H_SHFOXP1 229 bp overlap
ARID1A 4 datasets
ChIP MCF-7 GSE123284.ARID1A.MCF-7 80 bp overlap
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 126 bp overlap
ChIP MCF-7_Fulvestrant GSE123284.ARID1A.MCF-7_Fulvestrant 144 bp overlap
ChIP endometrial-epithelial-cells GSE106660.ARID1A.endometrial-epithelial-cells 52 bp overlap
ASH2L 1 dataset
ChIP Hep-G2 ENCSR508LMH.ASH2L.Hep-G2 83 bp overlap
BRD4 5 datasets
ChIP PC-3_GDC-R_SAHA GSE137207.BRD4.PC-3_GDC-R_SAHA 130 bp overlap
ChIP SUM159PT_100nMtrametinib_4h GSE87418.BRD4.SUM159PT_100nMtrametinib_4h 100 bp overlap
ChIP SUM159PT_DMSO_48h GSE87418.BRD4.SUM159PT_DMSO_48h 137 bp overlap
ChIP SUM159PT_shMYC_DMSO_48h GSE87418.BRD4.SUM159PT_shMYC_DMSO_48h 70 bp overlap
ChIP SUM159PT_shMYC_dox_48h GSE87418.BRD4.SUM159PT_shMYC_dox_48h 229 bp overlap
CREB1 1 dataset
ChIP A-549 ENCSR000BRB.CREB1.A-549 88 bp overlap
EP300 1 dataset
ChIP PC-3 GSE147455.EP300.PC-3 110 bp overlap
ESR1 70 datasets
ChIP Ishikawa ENCSR000BQR.ESR1.Ishikawa 93 bp overlap
ChIP MCF-7 GSE76893.ESR1.MCF-7 164 bp overlap
ChIP MCF-7 GSE148277.ESR1.MCF-7 188 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 182 bp overlap
ChIP MCF-7 GSE45822.ESR1.MCF-7 122 bp overlap
ChIP MCF-7 GSE103023.ESR1.MCF-7 124 bp overlap
ChIP MCF-7 GSE41561.ESR1.MCF-7 101 bp overlap
ChIP MCF-7 GSE136302.ESR1.MCF-7 59 bp overlap
ChIP MCF-7-Luc-Y537S_E2 GSE78284.ESR1.MCF-7-Luc-Y537S_E2 72 bp overlap
ChIP MCF-7-Luc_E2 GSE78284.ESR1.MCF-7-Luc_E2 132 bp overlap
ChIP MCF-7_AZD2014 GSE103023.ESR1.MCF-7_AZD2014 92 bp overlap
ChIP MCF-7_D538G GSE148277.ESR1.MCF-7_D538G 105 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 164 bp overlap
ChIP MCF-7_E2 GSE59530.ESR1.MCF-7_E2 111 bp overlap
ChIP MCF-7_E2 GSE60270.ESR1.MCF-7_E2 122 bp overlap
ChIP MCF-7_E2 GSE72249.ESR1.MCF-7_E2 136 bp overlap
ChIP MCF-7_E2 GSE108883.ESR1.MCF-7_E2 154 bp overlap
ChIP MCF-7_E2 GSE68356.ESR1.MCF-7_E2 174 bp overlap
ChIP MCF-7_E2 GSE102410.ESR1.MCF-7_E2 141 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 132 bp overlap
ChIP MCF-7_E2 GSE71276.ESR1.MCF-7_E2 119 bp overlap
ChIP MCF-7_E2 ERP000901.ESR1.MCF-7_E2 94 bp overlap
ChIP MCF-7_E2 ERP000380.ESR1.MCF-7_E2 110 bp overlap
ChIP MCF-7_E2-10min-ERalpha GSE94023.ESR1.MCF-7_E2-10min-ERalpha 95 bp overlap
ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 113 bp overlap
ChIP MCF-7_E2-320min-ERalpha GSE94023.ESR1.MCF-7_E2-320min-ERalpha 50 bp overlap
ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 132 bp overlap
ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 114 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 119 bp overlap
ChIP MCF-7_E2PG GSE68356.ESR1.MCF-7_E2PG 193 bp overlap
ChIP MCF-7_E2_30min GSE108883.ESR1.MCF-7_E2_30min 229 bp overlap
ChIP MCF-7_E2_3h GSE108883.ESR1.MCF-7_E2_3h 136 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 88 bp overlap
ChIP MCF-7_E2_45min GSE109820.ESR1.MCF-7_E2_45min 192 bp overlap
ChIP MCF-7_E2_90min GSE109820.ESR1.MCF-7_E2_90min 229 bp overlap
ChIP MCF-7_E2_TNF GSE59530.ESR1.MCF-7_E2_TNF 85 bp overlap
ChIP MCF-7_E2_talen GSE94493.ESR1.MCF-7_E2_talen 82 bp overlap
ChIP MCF-7_ER_t30 GSE119057.ESR1.MCF-7_ER_t30 60 bp overlap
ChIP MCF-7_ER_t50 GSE119057.ESR1.MCF-7_ER_t50 106 bp overlap
ChIP MCF-7_GLYC ERP002305.ESR1.MCF-7_GLYC 110 bp overlap
ChIP MCF-7_ICI GSE125594.ESR1.MCF-7_ICI 100 bp overlap
ChIP MCF-7_ICI GSE108883.ESR1.MCF-7_ICI 84 bp overlap
ChIP MCF-7_LTED_E2 GSE86538.ESR1.MCF-7_LTED_E2 50 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 129 bp overlap
ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 120 bp overlap
ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 143 bp overlap
ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 56 bp overlap
ChIP MCF-7_SHFOXA1_E2 ERP000380.ESR1.MCF-7_SHFOXA1_E2 116 bp overlap
ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 153 bp overlap
ChIP MCF-7_SIGATA_E2 GSE40129.ESR1.MCF-7_SIGATA_E2 152 bp overlap
ChIP MCF-7_TamR GSE128445.ESR1.MCF-7_TamR 131 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 184 bp overlap
ChIP MCF-7_estradiol-Dex_4h GSE99626.ESR1.MCF-7_estradiol-Dex_4h 122 bp overlap
ChIP MCF-7_estradiol-progesterone_4h GSE99626.ESR1.MCF-7_estradiol-progesterone_4h 148 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 189 bp overlap
ChIP MCF-7_estrogen GSE133941.ESR1.MCF-7_estrogen 82 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 132 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 167 bp overlap
ChIP MCF-7_jc5852 GSE126004.ESR1.MCF-7_jc5852 178 bp overlap
ChIP MCF-7_jc5853 GSE126004.ESR1.MCF-7_jc5853 152 bp overlap
ChIP MCF-7_jc5854 GSE126004.ESR1.MCF-7_jc5854 106 bp overlap
ChIP MCF-7_jc5855 GSE126004.ESR1.MCF-7_jc5855 150 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 179 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 70 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 56 bp overlap
ChIP MCF-7_shCtrl GSE125594.ESR1.MCF-7_shCtrl 103 bp overlap
ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 144 bp overlap
ChIP MCF-7_shYAP1 GSE125594.ESR1.MCF-7_shYAP1 132 bp overlap
ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 154 bp overlap
ChIP MDA-MB-134-VI_FI GSE109103.ESR1.MDA-MB-134-VI_FI 136 bp overlap
ESR1_D538G 2 datasets
ChIP MCF-7_dox GSE94493.ESR1_D538G.MCF-7_dox 96 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_D538G.MCF-7_dox_E2 66 bp overlap
ESR1_Y537N 2 datasets
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 148 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 129 bp overlap
ESR1_Y537S 2 datasets
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 124 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 81 bp overlap
ESR1_pS118 1 dataset
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 176 bp overlap
FOS 1 dataset
ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 203 bp overlap
FOXA1 15 datasets
ChIP 22Rv1 GSE96652.FOXA1.22Rv1 83 bp overlap
ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 141 bp overlap
ChIP CFPAC-1_FOXA2-KO GSE119930.FOXA1.CFPAC-1_FOXA2-KO 148 bp overlap
ChIP MCF-7_ETOH GSE23852.FOXA1.MCF-7_ETOH 95 bp overlap
ChIP MCF-7_JC4693 GSE126004.FOXA1.MCF-7_JC4693 105 bp overlap
ChIP MCF-7_JC4695 GSE126004.FOXA1.MCF-7_JC4695 63 bp overlap
ChIP PDAC GSE64557.FOXA1.PDAC 98 bp overlap
ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 202 bp overlap
ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 194 bp overlap
ChIP VCaP_DHT24H GSE58428.FOXA1.VCaP_DHT24H 131 bp overlap
ChIP breast_tumor_Female_1 GSE104399.FOXA1.breast_tumor_Female_1 121 bp overlap
ChIP breast_tumor_Male_14 GSE104399.FOXA1.breast_tumor_Male_14 125 bp overlap
ChIP breast_tumor_Male_19 GSE104399.FOXA1.breast_tumor_Male_19 71 bp overlap
ChIP breast_tumor_Male_4 GSE104399.FOXA1.breast_tumor_Male_4 196 bp overlap
ChIP primary-breast-cancer_B1_DSG GSE114737.FOXA1.primary-breast-cancer_B1_DSG 183 bp overlap
FOXA2 7 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 145 bp overlap
ChIP CFPAC-1 GSE119930.FOXA2.CFPAC-1 72 bp overlap
ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 115 bp overlap
ChIP CFPAC-1_HNF1B-KO GSE119930.FOXA2.CFPAC-1_HNF1B-KO 62 bp overlap
ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 100 bp overlap
ChIP Caco-2 GSE66218.FOXA2.Caco-2 100 bp overlap
ChIP DE DE-FOXA2-2 229 bp overlap
GATA3 3 datasets
ChIP MCF-7 GSE122847.GATA3.MCF-7 142 bp overlap
ChIP MCF-7_E2 GSE29073.GATA3.MCF-7_E2 89 bp overlap
ChIP breast_tumor_Male_21 GSE104399.GATA3.breast_tumor_Male_21 80 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 229 bp overlap
ChIP DE DE-GATA4-2 229 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 229 bp overlap
GATA6 8 datasets
ChIP AGS GSE51705.GATA6.AGS 217 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 198 bp overlap
ChIP DE DE-GATA6-1 229 bp overlap
ChIP DE DE-GATA6-2 229 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 229 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 222 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 229 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 229 bp overlap
GRHL2 1 dataset
ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 69 bp overlap
HOXB13 1 dataset
ChIP prostate_2480_T GSE130408.HOXB13.prostate_2480_T 59 bp overlap
JUNB 1 dataset
ChIP CFPAC-1 GSE119930.JUNB.CFPAC-1 51 bp overlap
MED1 2 datasets
ChIP hMSC-TERT4_osteoblast-D1 GSE113253.MED1.hMSC-TERT4_osteoblast-D1 96 bp overlap
ChIP hMSC-TERT4_osteoblast-D7 GSE113253.MED1.hMSC-TERT4_osteoblast-D7 114 bp overlap
NCOA2 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA2.MCF-7_E2 109 bp overlap
NCOA3 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 82 bp overlap
NR2F2 1 dataset
ChIP MCF-7 ENCSR000BUY.NR2F2.MCF-7 66 bp overlap
NRIP1 2 datasets
ChIP MCF-7 ERP005838.NRIP1.MCF-7 88 bp overlap
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 127 bp overlap
PSIP1 1 dataset
ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 86 bp overlap
RUNX1 1 dataset
ChIP VCaP_DHT24H GSE58428.RUNX1.VCaP_DHT24H 73 bp overlap
SFPQ 1 dataset
ChIP LTAD_EtOH GSE94577.SFPQ.LTAD_EtOH 178 bp overlap
SIN3A 1 dataset
ChIP SK-N-SH ENCSR000BPB.SIN3A.SK-N-SH 58 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 136 bp overlap
SMARCA2 1 dataset
ChIP NPC_R1159Q_AM GSE122631.SMARCA2.NPC_R1159Q_AM 135 bp overlap
SMARCA4 2 datasets
ChIP 501-mel_SHCTR GSE61965.SMARCA4.501-mel_SHCTR 115 bp overlap
ChIP A-549_AG15684 GSE132290.SMARCA4.A-549_AG15684 94 bp overlap
SMARCB1 4 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 143 bp overlap
ChIP MCF-7_DCDT GSE123284.SMARCB1.MCF-7_DCDT 115 bp overlap
ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 82 bp overlap
ChIP proliferating-human-fibroblast_ASO_Ctrl GSE131711.SMARCB1.proliferating-human-fibroblast_ASO_Ctrl 97 bp overlap
SNAI2 1 dataset
ChIP PC-9_2DF GSE131687.SNAI2.PC-9_2DF 217 bp overlap
TCF12 1 dataset
ChIP A-549 ENCSR000BQQ.TCF12.A-549 54 bp overlap
YY1AP1 1 dataset
ChIP MCF-7_E2 GSE125594.YY1AP1.MCF-7_E2 55 bp overlap
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