chr11 : 59,804,004 – 59,805,149

1,145 bp 74 TFs 1 linked gene

This 1.1 kb open chromatin element is linked to MRPL16 and is bound by 74 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
MRPL16		5.6 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

BCL6 1 dataset

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 682 bp overlap

CEBPA 1 dataset

ChIP SKH1_E2 GSE102697.CEBPA.SKH1_E2 262 bp overlap

CRX 1 dataset

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 215 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF262VBH 251 bp overlap

DDX5 1 dataset

ChIP NTERA2 GSE58641.DDX5.NTERA2 279 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 250 bp overlap

ChIP hESC GSE26097.EOMES.hESC 224 bp overlap

EP300 2 datasets

ChIP AML GSE131939.EP300.AML 104 bp overlap

ChIP AML_shaml1-eto GSE131939.EP300.AML_shaml1-eto 109 bp overlap

ERF::FIGLA 1 dataset

Motif DE_60h DE_60h-ERFFIGLA_MA1934.2 13 bp overlap

ERF::FOXI1 1 dataset

Motif DE_60h DE_60h-ERFFOXI1_MA1935.2 10 bp overlap

ETV2::FIGLA 1 dataset

Motif DE_60h DE_60h-ETV2FIGLA_MA1941.2 13 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_60h DE_60h-ETV2FOXI1_MA1942.2 11 bp overlap

ETV5::FIGLA 1 dataset

Motif DE_60h DE_60h-ETV5FIGLA_MA1945.2 14 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_60h DE_60h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 813 bp overlap

ChIP DE DE-FOXA2-2 541 bp overlap

ChIP DE DE-FOXA2-2 276 bp overlap

FOXD2 2 datasets

Motif DE_60h DE_60h-FOXD2_MA0847.4 11 bp overlap

Motif DE_72h DE_72h-FOXD2_MA0847.4 11 bp overlap

GATA2 2 datasets

ChIP SKH1 GSE87283.GATA2.SKH1 502 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.GATA2.SKH1_RUNX1-EVI1_KD 264 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 928 bp overlap

ChIP DE DE-GATA4-2 1087 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 286 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 938 bp overlap

ChIP DE DE-GATA6-2 1041 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 391 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 1011 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 440 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 839 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 263 bp overlap

Gli1 1 dataset

Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap

Gli2 1 dataset

Motif DE_60h DE_60h-Gli2_MA0734.4 9 bp overlap

HAND2 1 dataset

Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap

HOXC11 2 datasets

Motif DE_60h DE_60h-HOXC11_MA0651.3 11 bp overlap

Motif DE_72h DE_72h-HOXC11_MA0651.3 11 bp overlap

IKZF1 1 dataset

Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap

Irf1 3 datasets

Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap

Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap

KLF4 1 dataset

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 179 bp overlap

LDB1 2 datasets

ChIP Kasumi-1_ctrl GSE121280.LDB1.Kasumi-1_ctrl 273 bp overlap

ChIP Kasumi-1_siRE GSE121280.LDB1.Kasumi-1_siRE 464 bp overlap

LMO2 2 datasets

ChIP Kasumi-1_SICTR GSE60130.LMO2.Kasumi-1_SICTR 317 bp overlap

ChIP Kasumi-1_SIRUNX1ETO GSE60130.LMO2.Kasumi-1_SIRUNX1ETO 325 bp overlap

MECOM 2 datasets

ChIP SKH1_CEBPA-ER GSE102697.MECOM.SKH1_CEBPA-ER 197 bp overlap

ChIP SKH1_E2 GSE102697.MECOM.SKH1_E2 146 bp overlap

MXI1 3 datasets

Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap

Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap

Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap

MYB 1 dataset

ChIP Loucy GSE94000.MYB.Loucy 329 bp overlap

MYC 1 dataset

ChIP CD34 GSE85488.MYC.CD34 173 bp overlap

NEUROD1 1 dataset

Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap

NR2F1 1 dataset

Motif DE_60h DE_60h-NR2F1_MA1537.2 13 bp overlap

Neurod2 1 dataset

Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap

Nr1h3::Rxra 2 datasets

Motif DE_60h DE_60h-Nr1h3Rxra_MA0494.2 16 bp overlap

Motif DE_72h DE_72h-Nr1h3Rxra_MA0494.2 16 bp overlap

PAF1 1 dataset

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 293 bp overlap

PHF19 1 dataset

ChIP DU145_CTR GSE135623.PHF19.DU145_CTR 233 bp overlap

PML 2 datasets

ChIP K-562 ENCSR000BQY.PML.K-562 167 bp overlap

ChIP K-562 ENCSR000BQY.PML.K-562 147 bp overlap

POLR2A 3 datasets

ChIP K562 ENCFF137JSF 390 bp overlap

ChIP K562 ENCFF137JSF 491 bp overlap

ChIP K562 ENCFF215CWW 393 bp overlap

POLR2G 1 dataset

ChIP K562 ENCFF047BLG 127 bp overlap

POLR2H 2 datasets

ChIP K562 ENCFF377NHG 707 bp overlap

ChIP K562 ENCFF377NHG 310 bp overlap

POU2F2 1 dataset

ChIP HNPC_UNDIF GSE74814.POU2F2.HNPC_UNDIF 136 bp overlap

Pparg::Rxra 1 dataset

Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap

Ptf1A 1 dataset

Motif DE_60h DE_60h-Ptf1A_MA1618.2 9 bp overlap

RBFOX2 2 datasets

ChIP K562 ENCFF196WTG 179 bp overlap

ChIP K562 ENCFF967GRF 179 bp overlap

RUNX1 9 datasets

ChIP AML_Blast GSE60130.RUNX1.AML_Blast 190 bp overlap

ChIP CD34 GSE64862.RUNX1.CD34 190 bp overlap

ChIP ME-1 GSE117138.RUNX1.ME-1 295 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.RUNX1.ME-1_CBFB-MYH11-KD 390 bp overlap

ChIP ME-1_Con GSE128771.RUNX1.ME-1_Con 390 bp overlap

ChIP ME-1_KD GSE128771.RUNX1.ME-1_KD 295 bp overlap

ChIP SKH1 GSE87283.RUNX1.SKH1 191 bp overlap

ChIP SKH1_10d GSE87283.RUNX1.SKH1_10d 296 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.RUNX1.SKH1_RUNX1-EVI1_KD 187 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1_CEBPA-ER GSE102697.RUNX1T1.Kasumi-1_CEBPA-ER 162 bp overlap

RXRB 1 dataset

Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap

RXRG 1 dataset

Motif DE_60h DE_60h-RXRG_MA0856.1 14 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 738 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 227 bp overlap

SOX17_M 2 datasets

ChIP DE_D2 DED2-SOX17-M_Batch_II 359 bp overlap

ChIP DE_D2 DED2-SOX17-M_Batch_II 265 bp overlap

SPI1 3 datasets

ChIP KG-1 GSE128834.SPI1.KG-1 190 bp overlap

ChIP Kasumi-1_SICTR GSE60130.SPI1.Kasumi-1_SICTR 283 bp overlap

ChIP Kasumi-1_SIRUNX1ETO GSE60130.SPI1.Kasumi-1_SIRUNX1ETO 324 bp overlap

SPIC 1 dataset

Motif DE_60h DE_60h-SPIC_MA0687.2 13 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 357 bp overlap

SUPT5H 7 datasets

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 372 bp overlap

ChIP HCT-116_DMSO GSE138548.SUPT5H.HCT-116_DMSO 183 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 153 bp overlap

ChIP K562 ENCFF902PAW 272 bp overlap

ChIP U2OS_siCtrl GSE115365.SUPT5H.U2OS_siCtrl 126 bp overlap

Spi1 1 dataset

Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap

Stat2 1 dataset

Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 198 bp overlap

TAL1::TCF3 1 dataset

Motif DE_60h DE_60h-TAL1TCF3_MA0091.2 10 bp overlap

TCF12 1 dataset

ChIP ME-1 GSE46044.TCF12.ME-1 330 bp overlap

TCF3 1 dataset

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 404 bp overlap

TFAP4::ETV1 1 dataset

Motif DE_60h DE_60h-TFAP4ETV1_MA1966.2 13 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_60h DE_60h-TFAP4FLI1_MA1967.2 14 bp overlap

THRA 2 datasets

Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap

Motif DE_72h DE_72h-THRA_MA1969.2 18 bp overlap

TWIST1 1 dataset

Motif DE_60h DE_60h-TWIST1_MA1123.3 8 bp overlap

Tcf21 1 dataset

Motif DE_60h DE_60h-Tcf21_MA0832.2 10 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 181 bp overlap

ZBTB6 1 dataset

Motif DE_60h DE_60h-ZBTB6_MA1581.2 9 bp overlap

ZNF362 1 dataset

ChIP HEK293 ENCSR715QNO.ZNF362.HEK293 69 bp overlap

ZNF573 1 dataset

ChIP HEK293T GSE78099.ZNF573.HEK293T 176 bp overlap

Zic1::Zic2 2 datasets

Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Zic3 2 datasets

Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap